4,4'-Dicarboxy-m-terphenyl | 64896-51-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-Dicarboxy-m-terphenyl
• 英文别名: m-Terphenyl-4,4' dicarboxylic acid；4-(4-carboxyphenyl)-2-phenylbenzoic acid
• CAS: 64896-51-1
• 化学式: C₂₀H₁₄O₄
• 分子量: 318.329
• InChiKey: DIIHKMXFHFOLFD-UHFFFAOYSA-N

物化性质

• 熔点：
  362-364 °C (decomp)
• 沸点：
  527.7±45.0 °C(Predicted)
• 密度：
  1.298±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4,4'-Dicarboxy-m-terphenyl 、 碘甲烷 生成 4,4'-Dimethoxycarbonyl-m-terphenyl
  参考文献：
  名称：

  Rabilloud,G. et al., Bulletin de la Societe Chimique de France, 1977, p. 281 - 287

  摘要：

  DOI：
• 作为产物：
  描述：

  4,4'-Dibromo-m-terphenyl 在 N-甲基吡咯烷酮 、 sodium hypobromide 作用下， 以 1,4-二氧六环 、 二氯甲烷 为溶剂， 生成 4,4'-Dicarboxy-m-terphenyl
  参考文献：
  名称：

  Rabilloud,G. et al., Bulletin de la Societe Chimique de France, 1977, p. 281 - 287

  摘要：

  DOI：

文献信息

• High pressure balloon
  申请人：BOSTON SCIENTIFIC SCIMED, INC.

  公开号：US10099039B2

  公开（公告）日：2018-10-16

  Composite fiber reinforced balloons for medical devices are prepared by applying a web of fibers to the exterior of a preformed underlayer balloon, encasing the web with a matrix material to form an assembly, and inserting the assembly into a preformed outer layer balloon to form the composite balloon.

  用于医疗器械的复合纤维增强球囊的制备方法是：在预制的底层球囊外部涂上纤维网，用基质材料包裹纤维网以形成组件，然后将组件插入预制的外层球囊以形成复合球囊。
• Medical balloon with reinforcing member
  申请人：BOSTON SCIENTIFIC SCIMED, INC.

  公开号：US10709877B2

  公开（公告）日：2020-07-14

  Catheter assemblies and methods for making and using catheter assemblies are disclosed. An example a catheter assembly includes a catheter shaft and a balloon attached to the catheter shaft. The balloon includes a body and a proximal waist portion. The proximal waist portion has a proximal end. The catheter assembly also has a fiber braid including one or more individual filaments disposed along the balloon. The fiber braid has a proximal end aligned with the proximal end of the waist portion. The catheter assembly also has a polymer sleeve disposed on the catheter shaft, wherein in the polymer sleeve abuts the proximal end of the balloon waist and the proximal end of the braid.

  本文公开了导管组件以及制造和使用导管组件的方法。导管组件的一个示例包括导管轴和连接到导管轴上的球囊。球囊包括一个主体和一个近端腰部。近端腰部有一个近端。导管组件还具有纤维编织层，包括沿球囊布置的一根或多根单丝。纤维编织物的近端与腰部的近端对齐。导管组件还具有设置在导管轴上的聚合物套管，其中聚合物套管与球囊腰部的近端和编织物的近端相邻。
• Medical balloon
  申请人：BOSTON SCIENTIFIC SCIMED, INC.

  公开号：US10849629B2

  公开（公告）日：2020-12-01

  Composite expandable medical balloons and methods for forming composite expandable medical balloons are disclosed. An example composite expandable medical balloon may include a base balloon. A fiber braid may be disposed along the base balloon. The base balloon may have a first length prior to heat sterilization of the composite expandable medical balloon, and a second length after heat sterilization of the composite expandable medical balloon. The second length may be at least 95% of the first length.

  本文公开了复合可膨胀医用球囊和形成复合可膨胀医用球囊的方法。复合可膨胀医用球囊的一个示例可包括一个基底球囊。纤维编织物可沿基底球囊布置。在对复合可膨胀医用球囊进行热消毒之前，基底球囊可具有第一长度，而在对复合可膨胀医用球囊进行热消毒之后，基底球囊可具有第二长度。第二长度可以是第一长度的至少 95%。
• Stent and stent delivery system with improved deliverability
  申请人：McClain James B.

  公开号：US11369498B2

  公开（公告）日：2022-06-28

  Stent delivery systems having improved deliverability comprising an elongate member having an inflation lumen and a guidewire lumen therein; a balloon having an interior that is in fluid communication with the inflation lumen; and a stent comprising a coating mounted on the balloon. Methods for making stent delivery systems having improved deliverability. Methods for delivering two stent delivery systems concurrently through a guiding catheter, each stent delivery system comprising elongate member having an inflation lumen and a guidewire lumen therein, a balloon having an interior that is in fluid communication with the inflation lumen, and a stent comprising a coating mounted on the balloon. Stent coatings may comprise a pharmaceutical agent at least a portion of which is in crystalline form.

  具有更佳输送能力的支架输送系统，包括一个具有充气腔和导丝腔的细长部件；一个具有与充气腔流体相通的内部的球囊；以及一个包括安装在球囊上的涂层的支架。制造具有更好输送能力的支架输送系统的方法。通过导引导管同时输送两个支架输送系统的方法，每个支架输送系统包括具有充气腔和导丝腔的细长部件、具有与充气腔流体相通的内部的球囊、以及包括安装在球囊上的涂层的支架。支架涂层可包括药剂，其中至少有一部分为晶体状。
• Laminate catheter balloons with additive burst strength and methods for preparation of same
  申请人：——

  公开号：US20020081406A1

  公开（公告）日：2002-06-27

  A laminate balloon comprising at least two layers of separately oriented thermoplastic polymer material, which are coextensive over the body of the balloon. The two layers may be made of different polymer materials, including an underlying layer made of a low compliant, high strength polymer, such as PET, and an overlying layer of a softer and more flexible polymer material relative to the first polymer material, such as a polyester-polyether block copolymer. The balloon structures have an additive burst pressure, meaning that they are stronger than a single-layer reference balloon corresponding to the underlying polymer layer. The balloons are characterized by a combination of flexibility and surface softness which allows catheters to track down into lesions relatively easily, puncture resistance, abrasion resistance and refoldability, in addition to low compliance and high burst strength. The balloons may be prepared with generally linear or with stepped compliance profiles. Methods of preparation of such balloons are also disclosed.

  一种层压气球，包括至少两层分别取向的热塑性聚合物材料，这两层材料在气球主体上共存。这两层可由不同的聚合物材料制成，包括由低顺应性、高强度聚合物（如 PET）制成的底层，以及由相对于第一层聚合物材料更软、更柔韧的聚合物材料（如聚酯-聚醚嵌段共聚物）制成的上层。球囊结构具有附加爆破压力，这意味着它们比与底层聚合物层相对应的单层参考球囊更强。除了低顺应性和高爆破强度外，这些球囊还具有柔韧性和表面柔软性的特点，这使得导管可以相对容易地追踪到病变部位、抗穿刺性、耐磨性和可再折叠性。球囊可按一般线性或阶梯顺应性曲线制备。此外，还公开了此类球囊的制备方法。