2-[Carboxymethyl-[4-(dimethylamino)benzoyl]amino]acetic acid | 1377011-24-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[Carboxymethyl-[4-(dimethylamino)benzoyl]amino]acetic acid
• CAS: 1377011-24-9
• 化学式: C₁₃H₁₆N₂O₅
• 分子量: 280.28
• InChiKey: OFCCWICSMUBSOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  98.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  4-二甲氨基苯甲酰氯 在 三乙胺 、 sodium hydroxide 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 生成 2-[Carboxymethyl-[4-(dimethylamino)benzoyl]amino]acetic acid
  参考文献：
  名称：

  A highly selective chemosensor for copper ion based on ICT fluorescence

  摘要：

  Simple structural compounds 1 to 3 were synthesized. The presence of Cu2+ resulted in the fluorescence and absorption spectra change of 1 and 2, which indicated that 1 and 2 showed a highly selective response to Cu2+ over other metal ions. However, 3 showed no selectivity for metal ions, which means that the compound could bind with several metal ions, such as, Ni2+, Zn2+, Cd2+, Hg2+, Pb2+, Fe3+, Mg2+, Ca2+, and Co2+, except Cu2+ and Ag+. The different spectral responses were attributed to the difference in binding sites for 1 and 3. (C) 2012 Fang Ying Wu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2012.03.007

文献信息

• A highly selective chemosensor for copper ion based on ICT fluorescence
  作者：Fang Ying Wu、Sheng Gen Cao、Cai Xia Xie

  DOI：10.1016/j.cclet.2012.03.007

  日期：2012.5

  Simple structural compounds 1 to 3 were synthesized. The presence of Cu2+ resulted in the fluorescence and absorption spectra change of 1 and 2, which indicated that 1 and 2 showed a highly selective response to Cu2+ over other metal ions. However, 3 showed no selectivity for metal ions, which means that the compound could bind with several metal ions, such as, Ni2+, Zn2+, Cd2+, Hg2+, Pb2+, Fe3+, Mg2+, Ca2+, and Co2+, except Cu2+ and Ag+. The different spectral responses were attributed to the difference in binding sites for 1 and 3. (C) 2012 Fang Ying Wu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.