(3-fluoro-2-hydroxyphenyl)phenylmethanone | 183280-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3-fluoro-2-hydroxyphenyl)phenylmethanone
• 英文别名: (3-Fluoro-2-hydroxyphenyl)-phenylmethanone
• CAS: 183280-19-5
• 化学式: C₁₃H₉FO₂
• 分子量: 216.212
• InChiKey: FZYBFJJJLQNASQ-UHFFFAOYSA-N

物化性质

• 熔点：
  56°C
• 沸点：
  308.1±27.0 °C(Predicted)
• 密度：
  1.270±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  R(-)-Alpha-组胺二氢溴 、 (3-fluoro-2-hydroxyphenyl)phenylmethanone 以 乙腈 为溶剂， 以79%的产率得到
  参考文献：
  名称：

  Krause; Rouleau; Stark, Pharmazie, 1996, vol. 51, # 10, p. 720 - 726

  摘要：

  DOI：
• 作为产物：
  描述：

  benzoic acid 2-fluorophenyl ester 在 三氯化铝 作用下， 以25%的产率得到(3-fluoro-2-hydroxyphenyl)phenylmethanone
  参考文献：
  名称：

  Krause; Rouleau; Stark, Pharmazie, 1996, vol. 51, # 10, p. 720 - 726

  摘要：

  DOI：

文献信息

• Purification of 4-fluoro-4'-hydroxy-benzophenone
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0167240A1

  公开（公告）日：1986-01-08

  A mixture of isomers offluoro-4'-hydroxybenzophenone are dissolved in an aqueous solution of a base, for example sodium hydroxide, and sufficient acid is added to reduce the pH to not less than 9 and to precipitate 4-fiuoro-4'-hydroxybenzophenone having a reduced proportion of other isomers.

  将非氟-4'-羟基二苯甲酮异构体混合物溶于碱（例如氢氧化钠）水溶液中，然后加入足量的酸，使 pH 值降至不低于 9，并沉淀出其他异构体比例降低的 4-氟-4'-羟基二苯甲酮。
• Aromatic polyetherketones
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0152161A1

  公开（公告）日：1985-08-21

  A crystallisable thermoplastic aromatic polyetherketone, the polymeric chain of which contains the repeat unit where Ar, and Ar2 are aromatic radicals which may be the same or different and comprise at least one aromatic ring, the polymeric chains having terminal ionic groups - A-X, where A is an anion and X is a metal cation. The anion is preferably selected from sulphonate, carboxylate, sulphinate, phosphonate, phosphate, phenate and thiophenate and the cation is preferably alkali metal or alkaline earth metal. The products may be used in blends with other polyetherketones as a nucleant for the other polyetherketones.

  一种可结晶的热塑性芳香族聚醚酮，其聚合物链包含重复单元 其中 Ar 和 Ar2 是芳香基，它们可以相同或不同，并包含至少一个芳香环，聚合链具有末端离子基团-A-X，其中 A 是阴离子，X 是金属阳离子。阴离子最好选自磺酸盐、羧酸盐、硫酸盐、膦酸盐、磷酸盐、苯酸盐和噻吩盐，阳离子最好是碱金属或碱土金属。产品可与其他聚醚酮混合使用，作为其他聚醚酮的成核剂。
• DENTAL RESIN COMPOSITE MATERIAL, METHOD FOR PRODUCING DENTAL RESIN COMPOSITE MATERIAL, AND POLYARYLETHERKETONE RESIN FOR PRODUCING DENTAL RESIN COMPOSITE MATERIAL
  申请人：Tokuyama Dental Corporation

  公开号：EP3527191A1

  公开（公告）日：2019-08-21

  Provided is a dental resin composite material reduced in darkness of its color tone, and also reduced in burning and color unevenness. Specifically provided are a dental resin composite material including 100 parts by mass of a polyaryletherketone resin, 10 parts by mass to 300 parts by mass of inorganic particles, and 90 ppm or less of an impurity having an aromatic ring, a method of producing the dental resin composite material, and a polyaryletherketone resin for producing a dental resin composite material, to be used for producing the dental resin composite material.

  本发明提供了一种牙科树脂复合材料，可降低其色调的暗度，还可降低灼烧和颜色不均匀度。具体地说，本发明提供了一种牙科树脂复合材料，其中包括 100 质量份的聚芳醚酮树脂、10 至 300 质量份的无机颗粒和 90 ppm 或以下的具有芳香环的杂质；一种生产该牙科树脂复合材料的方法；以及一种用于生产该牙科树脂复合材料的聚芳醚酮树脂。
• Dental resin composite material, method of producing dental resin composite material, and polyaryletherketone resin for producing dental resin composite material
  申请人：TOKUYAMA DENTAL CORPORATION

  公开号：US10813850B2

  公开（公告）日：2020-10-27

  A dental resin composite material is provided that is reduced in darkness of its color tone, and also reduced in burning and color unevenness. Specifically provided are a dental resin composite material including 100 parts by mass of a polyaryletherketone resin, 10 parts by mass to 300 parts by mass of inorganic particles, and 90 ppm or less of an impurity having an aromatic ring, a method of producing the dental resin composite material, and a polyaryletherketone resin for producing a dental resin composite material, to be used for producing the dental resin composite material.

  本发明提供了一种牙科树脂复合材料，可降低色调的暗度，并减少烧焦和颜色不均。具体而言，本发明提供了一种牙科树脂复合材料，其中包括 100 份（质量）的聚芳基醚酮树脂、10 份（质量）至 300 份（质量）的无机颗粒和 90 ppm 或以下的具有芳香环的杂质；一种生产该牙科树脂复合材料的方法；以及一种用于生产该牙科树脂复合材料的聚芳基醚酮树脂。
• Process for the preparation of 4-hydroxy-benzophenones
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0128692B1

  公开（公告）日：1988-03-02