4-[2-(4-Aminophenyl)-4,5-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]aniline | 1159374-32-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[2-(4-Aminophenyl)-4,5-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]aniline
• CAS: 1159374-32-9
• 化学式: C₃₀H₄₄N₂O₂Si₂
• 分子量: 520.863
• InChiKey: WJIBJZPBEKBNHA-UHFFFAOYSA-N

物化性质

• 熔点：
  150 °C
• 沸点：
  538.2±50.0 °C(predicted)
• 密度：
  1.022±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.95
• 重原子数：
  36
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  70.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-芘甲醛 、 4-[2-(4-Aminophenyl)-4,5-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]aniline 以 乙醇 为溶剂， 以75%的产率得到N-[4-[4,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-[4-(pyren-1-ylmethylideneamino)phenyl]phenyl]phenyl]-1-pyren-1-ylmethanimine
  参考文献：
  名称：

  Terphenyl based ‘Turn On’ fluorescent sensor for mercury

  摘要：

  New terphenyl-based derivative 4 with pyrene as a fluorophore has been synthesized and examined for its cation recognition abilities toward various cations by NMR and fluorescence spectroscopy. The results show that it has very high binding affinity (log beta = 5.12) and selectivity for mercury. A fluorescence enhancement of 375% was observed for the 4-Hg2+ system in THF. A Hg2+ selective electrode (ISE) was also formed which showed excellent selectivity over all the Other cations rested. The lower limit of detection is 2.1 x 10(-6) M. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.110
• 作为产物：
  描述：

  1,2-dibromo-4,5-bis(tert-butyldimethylsilyloxy)benzene 、 4-氨基苯硼酸频哪醇酯 在 bis-triphenylphosphine-palladium(II) chloride 、 水 、 potassium carbonate 作用下， 以 1,4-二氧六环 为溶剂， 以60%的产率得到4-[2-(4-Aminophenyl)-4,5-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]aniline
  参考文献：
  名称：

  Terphenyl based ‘Turn On’ fluorescent sensor for mercury

  摘要：

  New terphenyl-based derivative 4 with pyrene as a fluorophore has been synthesized and examined for its cation recognition abilities toward various cations by NMR and fluorescence spectroscopy. The results show that it has very high binding affinity (log beta = 5.12) and selectivity for mercury. A fluorescence enhancement of 375% was observed for the 4-Hg2+ system in THF. A Hg2+ selective electrode (ISE) was also formed which showed excellent selectivity over all the Other cations rested. The lower limit of detection is 2.1 x 10(-6) M. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.03.110

文献信息

• Terphenyl based fluorescent chemosensor for Cu2+ and F− ions employing excited state intramolecular proton transfer
  作者：Vandana Bhalla、Ruchi Tejpal、Manoj Kumar

  DOI：10.1016/j.tet.2010.11.083

  日期：2011.2

  A new terphenyl based bifunctional fluorescent chemosensor 3a has been synthesized, which demonstrates selective optical recognition of Cu2+ and F- ions in two contrasting modes. The compound shows highly selective 'On-Off' switchable behavior toward Cu2+ ions and 'On-Off-On' behavior toward F- ions among various cations and anions tested. The detection limits of chemosensor for Cu2+ and F- ions are found to be 100 nM and 10 nM, respectively. (C) 2010 Elsevier Ltd. All rights reserved.