Dicyclododecylamin | 1781-77-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Dicyclododecylamin
• 英文别名: N-cyclododecylcyclododecanamine
• CAS: 1781-77-7
• 化学式: C₂₄H₄₇N
• 分子量: 349.644
• InChiKey: KXMSXUUXVXVSHS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  nitrocyclododecane 在 copper chromite 、 Lindlar's catalyst 氢气 、 氯化铵 、 锌 作用下， 以 四氢呋喃 、 水 为溶剂， 生成 Dicyclododecylamin
  参考文献：
  名称：

  Meister,H., Justus Liebigs Annalen der Chemie, 1964, vol. 679, p. 83 - 94

  摘要：

  DOI：

文献信息

• Selective Synthesis of Primary Amines by Reductive Amination of Ketones with Ammonia over Supported Pt catalysts
  作者：Yoichi Nakamura、Kenichi Kon、Abeda Sultana Touchy、Ken-ichi Shimizu、Wataru Ueda

  DOI：10.1002/cctc.201402996

  日期：2015.3

  Supported platinum catalysts are studied for the reductive amination of ketones under ammonia and hydrogen. For a model reaction with 2‐adamantanone, Pt‐loaded MoOx/TiO2 (Pt‐MoOx/TiO2) shows the highest yield of primary amine. The catalyst is effective for the selective transformation of various aliphatic and aromatic ketones to the corresponding primary amines, which demonstrates the first example

  对负载的铂催化剂进行了研究，以在氨和氢下将酮还原胺化。对于与2-金刚烷酮的模型反应，负载Pt的MoO x / TiO 2（Pt-MoO x / TiO 2）显示出最高的伯胺收率。该催化剂对于将各种脂族和芳族酮选择性转化为相应的伯胺是有效的，这证明了通过该反应选择性合成伯胺的第一个实例。在催化剂上吸附的丙酮的红外光谱中，胺的产率随CO伸缩带负移的增加而增加，这表明载体材料上的路易斯酸位在该催化体系中起着重要的作用。
• PRODUCTION METHOD FOR HYDROXY-CARBOXYLIC ACID AMIDE COMPOUND, AND NOVEL ARYLBORONIC ACID COMPOUND
  申请人：National University Corporation Nagoya University

  公开号：EP2816026A1

  公开（公告）日：2014-12-24

  A method for production of hydroxycarboxylic acid amide compounds, comprising performing amide condensation between an α- or β-hydroxycarboxylic acid compound and an amine compound in the presence as a catalyst of an alkylboronic acid represented by R3B(OH)2 (wherein R3 is a primary alkyl group) or an arylboronic acid compound to produce a hydroxycarboxylic acid amide compound, the arylboronic acid compound being represented by Formula (1): (in Formula (1), -(CH2)nNR1R2 is bonded at an ortho position or a para position, n is 1 or 2, R1 is a tertiary alkyl group, R2 is a secondary or tertiary alkyl group, and -NR1R2 may be a ring).

  一种生产羟基羧酸酰胺化合物的方法，包括在以 R3B(OH)2（其中 R3 为伯烷基）为代表的烷基硼酸或芳基硼酸化合物作为催化剂的存在下，在 α- 或 β- 羟基羧酸化合物和胺化合物之间进行酰胺缩合，生成羟基羧酸酰胺化合物，芳基硼酸化合物由式（1）表示： (式(1)中，-(CH2)nNR1R2键合在正位或对位，n为1或2，R1为叔烷基，R2为仲烷基或叔烷基，-NR1R2可以是一个环)。
• METHOD FOR PRODUCTION OF HYDROXYCARBOXYLIC ACID AMIDE COMPOUNDS AND NOVEL ARYLBORONIC ACID COMPOUND
  申请人：NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY

  公开号：US20150011766A1

  公开（公告）日：2015-01-08

  A method for production of hydroxycarboxylic acid amide compounds, including performing amide condensation between an α- or β-hydroxycarboxylic acid compound and an amine compound in the presence as a catalyst of an alkylboronic acid represented by R 3 B(OH) 2 (wherein R 3 is a primary alkyl group) or an arylboronic acid compound to produce a hydroxycarboxylic acid amide compound, the arylboronic acid compound being represented by Formula (1): (in Formula (1), —(CH 2 ) n NR 1 R 2 is bonded at an ortho position or a para position, n is 1 or 2, R 1 is a tertiary alkyl group, R 2 is a secondary or tertiary alkyl group, and —NR 1 R 2 may be a ring).
• US6455458B1
  申请人：——

  公开号：US6455458B1

  公开（公告）日：2002-09-24
• US9162972B2
  申请人：——

  公开号：US9162972B2

  公开（公告）日：2015-10-20