6-Chloro-2-(2-diethylamino-ethyl)-benzo[de]isoquinoline-1,3-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 6-Chloro-2-(2-diethylamino-ethyl)-benzo[de]isoquinoline-1,3-dione
• 英文别名: 6-Chloro-2-[2-(diethylamino)ethyl]benzo[de]isoquinoline-1,3-dione
• 化学式: C₁₈H₁₉ClN₂O₂
• 分子量: 330.814
• InChiKey: UJUWNQLOUDYZLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2-氨基乙基)吗啉 、 6-Chloro-2-(2-diethylamino-ethyl)-benzo[de]isoquinoline-1,3-dione 生成 2-(2-Diethylamino-ethyl)-6-(2-morpholin-4-yl-ethylamino)-benzo[de]isoquinoline-1,3-dione
  参考文献：
  名称：

  Silva, A. Prasanna de; Rice, Terence E., Chemical Communications, 1999, # 2, p. 163 - 164

  摘要：

  DOI：
• 作为产物：
  描述：

  4-氯萘二甲酰亚胺 、 N,N-二乙基乙二胺 以 甲苯 为溶剂， 反应 4.0h， 以60%的产率得到6-Chloro-2-(2-diethylamino-ethyl)-benzo[de]isoquinoline-1,3-dione
  参考文献：
  名称：

  Arenedicarboximide Building Blocks for Fluorescent Photoinduced Electron Transfer pH Sensors Applicable with Different Media and Communication Wavelengths

  摘要：

  N-(aminoalkyl)-4-chloronaphthalene-1,8-dicarboximides 1, N-(aminoalkyl)-4-acetamidonaphthalene- 1,8-dicarboximides 3 and N,N'-bis(aminoalkyl)-perylene-3,4:9,10-tetracarboxydiimides 4 show good fluorescent off-on switching in aqueous alcoholic solution with protons as required for fluorescent PET sensor design. The excitation wavelengths lie in the ultraviolet (lambda(max) = 345 and 351 nm) for 1 and 3 and in the blue-green (lambda(max) = 528, 492 and 461 nm) for 4: the emission wavelengths lie in the violet (lambda(max) = 405 nm) for 1, in the blue (lambda(max) = 474 nm) for 3 and in the yellow-orange (lambda(max) = 543 and 583 nm) for 4. Compound 4b shows substantial fluorescence enhancement with protons when immobilized in a poly(vinylchloride) matrix, provided that 2-nitrophenyloctyl ether plasticizer and potassium tetrakis(4-chlorophenyl)borate additive are present to prevent dye crystalization and to facilitate proton diffusion into the membrane, respectively.

  DOI：

  10.1002/(sici)1521-3765(19980904)4:9<1810::aid-chem1810>3.0.co;2-y

文献信息

• Arenedicarboximide Building Blocks for Fluorescent Photoinduced Electron Transfer pH Sensors Applicable with Different Media and Communication Wavelengths
  作者：Lynda M. Daffy、A. Prasanna de Silva、H. Q. Nimal Gunaratne、Christian Huber、P. L. Mark Lynch、Tobias Werner、Otto S. Wolfbeis

  DOI：10.1002/(sici)1521-3765(19980904)4:9<1810::aid-chem1810>3.0.co;2-y

  日期：1998.9.4

  N-(aminoalkyl)-4-chloronaphthalene-1,8-dicarboximides 1, N-(aminoalkyl)-4-acetamidonaphthalene- 1,8-dicarboximides 3 and N,N'-bis(aminoalkyl)-perylene-3,4:9,10-tetracarboxydiimides 4 show good fluorescent off-on switching in aqueous alcoholic solution with protons as required for fluorescent PET sensor design. The excitation wavelengths lie in the ultraviolet (lambda(max) = 345 and 351 nm) for 1 and 3 and in the blue-green (lambda(max) = 528, 492 and 461 nm) for 4: the emission wavelengths lie in the violet (lambda(max) = 405 nm) for 1, in the blue (lambda(max) = 474 nm) for 3 and in the yellow-orange (lambda(max) = 543 and 583 nm) for 4. Compound 4b shows substantial fluorescence enhancement with protons when immobilized in a poly(vinylchloride) matrix, provided that 2-nitrophenyloctyl ether plasticizer and potassium tetrakis(4-chlorophenyl)borate additive are present to prevent dye crystalization and to facilitate proton diffusion into the membrane, respectively.
• Silva, A. Prasanna de; Rice, Terence E., Chemical Communications, 1999, # 2, p. 163 - 164
  作者：Silva, A. Prasanna de、Rice, Terence E.

  DOI：——

  日期：——