2,4,7-三氯芴 | 7061-81-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: 2,4,7-三氯芴
• 英文名称: 2,4,7-trichlorofluorene
• 英文别名: 2,4,7-trichloro-fluorene；2,4,7-Trichlor-fluoren；2.4.7-Trichlor-fluoren；2,4,7-Trichlorfluoren；2,4,7-Trichloro-9h-fluorene
• CAS: 7061-81-6
• 化学式: C₁₃H₇Cl₃
• mdl: MFCD00010769
• 分子量: 269.558
• InChiKey: MXDREDYHROHHGJ-UHFFFAOYSA-N

物化性质

• 熔点：
  125-128 °C(lit.)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.076
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38

反应信息

• 作为反应物：
  描述：

  2,4,7-三氯芴 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 苯 为溶剂， 生成 2,4,7-Trichlor-9-bromfluoren
  参考文献：
  名称：

  Sengupta,S.K., Indian Journal of Chemistry, 1966, vol. 4, p. 235 - 238

  摘要：

  DOI：
• 作为产物：
  描述：

  2,7-二氯芴 在 氯仿 、 碘 、 氯 作用下， 生成 2,4,7-三氯芴
  参考文献：
  名称：

  Sieglitz; zit. bei Krollpfeiffer, Justus Liebigs Annalen der Chemie, 1923, vol. 430, p. 224 Anm. 2

  摘要：

  DOI：

文献信息

• Process for the preparation of N-phosphonomethylglycine and derivatives thereof
  申请人：Coleman P. James

  公开号：US20050054871A1

  公开（公告）日：2005-03-10

  N-phosphonomethylamines are produced by reaction of an amine substrate with a halomethylphosphonic acid or salt thereof, a hydroxymethylphosphonic acid or salt thereof, or a dehydrated self-ester dimer, trimer or oligomer of hydroxymethylphosphonic acid. Among the products that may be prepared according to the process are N-phosphonomethylaminocarboxylic acids such as (e.g.) glyphosate, N-phosphonomethylaminoalkanols such as (e.g.) hydroxyethlaminomethylphosphonic acid, and N-acylaminomethylphosphonic acids such as (e.g.) N-carbamylaminomethylphosphonic acid. Certain reactions are conducted with a substantial excess of amine reactant in order to drive the conversion while avoiding excessive formation of bis(N-phosphonomethyl)amine by-products. Other reactions use a secondary amine substrate (such as iminodiacetic acid) and can be conducted at substantial equimolar ratios of halomethylaminomethylphosphonic acid or hydroxyaminomethylphosphonic acid to secondary amine reactant without significant formation of bis(phosphonomethyl)amine by-products. Further disclosed is a process for the preparation of hydroxymethylphosphonic acid self-ester dimers, trimers and oligomers by azeotropic dehydration.

  N-磷酸甲基胺是通过胺底物与卤甲基膦酸或其盐、羟甲基膦酸或其盐，或羟甲基膦酸的脱水自酯二聚体、三聚体或寡聚体反应而制备的。根据该过程可制备的产品包括N-磷酸甲基氨基羧酸，如草甘膦，N-磷酸甲基氨基烷醇，如羟乙氨基甲基膦酸，以及N-酰氨基甲基膦酸，如N-氨基甲基膦酸。为了推动转化并避免过多形成双(N-磷酸甲基)胺副产物，某些反应中使用大量过量的胺试剂。其他反应使用二次胺底物（如亚胺二乙酸）并可在相当量的卤甲基氨甲膦酸或羟氨甲膦酸与二次胺试剂的摩尔比下进行，而不会显著形成双(磷酸甲基)胺副产物。还公开了通过共沸脱水制备羟甲基膦酸自酯二聚体、三聚体和寡聚体的方法。
• Method of preparing amino carboxylic acids
  申请人：——

  公开号：US20020002281A1

  公开（公告）日：2002-01-03

  Novel compounds, N,N′-bis(phosphonomethyl)-N,N′-bis(hydroxycarbonylmethyl)urea and N,N,N′,N′-tetrakis(hydroxycarbonylmethyl)urea, suitable for use in preparing N-acyl aminocarboxylic acids that can be readily converted to N-(phosphonomethyl)glycine are provided. The compounds may be formed by the reaction of bis-(phosophonomethyl)urea or urea respectively with carbon monoxide and formaldehyde in the presence of a carboxymethylation catalyst precursor and solvent.

  提供了一种新型化合物，即N,N'-双(膦甲基)-N,N'-双(羟基甲酰甲基)脲和N,N,N',N'-四(羟基甲酰甲基)脲，适用于制备可轻松转化为N-(膦甲基)甘氨酸的N-酰基氨基羧酸。这些化合物可以通过在羧甲基化催化剂前体和溶剂存在下，将双(膦甲基)脲或脲分别与一氧化碳和甲醛反应而形成。
• Fluorescent degree of cure monitors
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0400972A2

  公开（公告）日：1990-12-05

  A curable composition, the cure of which can be monitored optically, comprises at least one of a hydride curable silicone, an ethylenically unsaturated compound, and a cationically polymerizable monomer, and as cure monitor dibenzofulvene or derivatives thereof. The cure monitor is a latent fluorophore which reacts under the cure conditions to form a UV-detectable fluorophore. The invention also provides a method for measuring degree of cure of a polymeric material which can be a coating or an article.

  一种可固化组合物，其固化可通过光学监控，包括氢化物固化硅酮、乙烯基不饱和化合物和阳离子可聚合单体中的至少一种，以及作为固化监控剂的二苯并呋喃或其衍生物。固化监测剂是一种潜伏荧光团，它在固化条件下发生反应，形成一种可被紫外线检测到的荧光团。 本发明还提供了一种测量聚合材料固化程度的方法，这种材料可以是涂层，也可以是物品。
• Process for the preparation of N-(phosphonomethyl) glycine by oxidizing N-substituted N-(phosphonomethyl) glycine
  申请人：Monsanto Technology LLC

  公开号：EP1520857A1

  公开（公告）日：2005-04-06

  The present invention relates to a process for the preparation of an N-substituted N-(phosphonomethyl)glycine or a salt thereof, comprising: combining a source of H3PO3, a source of CH2O, and an N-substituted glycine salt; separating the resulting salt precipitate; adding a base to precipitate N-substituted N-(phosphonomethyl)glycine or the salt thereof; and separating the precipitated N-substituted N-(phosphonomethyl)glycine or salt thereof,    wherein the N-substituted N-(phosphonomethyl)glycine has formula (I): R1 and R2 are independently selected from the group consisting of hydrogen, halogen, -PO3R12R13, -SO3R14, -NO2, hydrocarbyl, and substituted hydrocarbyl other than -CO2R15; R6 is an agronomically acceptable cation; R12, R13, and R14 are independently selected from the group consisting of hydrogen, hydrocarbyl, and substituted hydrocarbyl; and R15 is selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl, and an agronomically acceptable cation.

  本发明涉及一种制备 N-取代的 N-(膦酰甲基)甘氨酸或其盐的工艺，包括： 将 H3PO3 源、CH2O 源和 N-取代的甘氨酸盐结合起来； 分离得到的盐沉淀； 加入碱沉淀 N-取代的 N-（膦酰甲基）甘氨酸或其盐；以及 分离沉淀的 N-取代的 N-(膦酰甲基)甘氨酸或其盐、 其中 N-取代的 N-(膦酰甲基)甘氨酸具有式 (I)： R1和R2独立地选自氢、卤素、-PO3R12R13、-SO3R14、-NO2、烃基和除-CO2R15以外的取代烃基组成的组；R6是农艺学上可接受的阳离子；R12、R13和R14独立地选自氢、烃基和取代烃基组成的组；R15选自氢、烃基、取代烃基和农艺学上可接受的阳离子组成的组。
• Oxidation catalyst for making glyphosate
  申请人：Monsanto Technology, LLC

  公开号：EP1716923A1

  公开（公告）日：2006-11-02

  The present invention relates to an oxidation catalyst comprising a noble metal and an electroactive molecular species absorbed thereon. The catalyst is particularly suitable in a process for converting N-substituted N-(phosphonomethyl) glycines, salts and esters thereof, to N-(phosphonomethyl) glycine, salts and esters thereof.

  本发明涉及一种氧化催化剂，由贵金属和吸附在其上的电活性分子物质组成。该催化剂特别适用于将 N-取代的 N-（膦酰甲基）甘氨酸、其盐类和酯类转化为 N-（膦酰甲基）甘氨酸、其盐类和酯类的工艺。