2,3-bis(phenylamino)naphthalene-1,4-dione | 80632-71-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,3-bis(phenylamino)naphthalene-1,4-dione
• 英文别名: 2,3-dianilino-1,4-naphthoquinone；2,3-dianilino-[1,4]naphthoquinone；2,3-Dianilino-[1,4]naphthochinon；2,3-Bis--1,4-naphthochinon；2,3-Dianilino-1,4-naphthochinon；2,3-Dianilinonaphthalene-1,4-dione
• CAS: 80632-71-9
• 化学式: C₂₂H₁₆N₂O₂
• 分子量: 340.381
• InChiKey: HTQYGVOVAUJXMF-UHFFFAOYSA-N

物化性质

• 熔点：
  232-233 °C
• 沸点：
  502.9±50.0 °C(Predicted)
• 密度：
  1.370±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,3-bis(phenylamino)naphthalene-1,4-dione 在 溶剂黄146 、 sodium nitrite 作用下， 生成 2-anilino-3-(N-nitroso-anilino)-[1,4]naphthoquinone
  参考文献：
  名称：

  Fries; Billig, Chemische Berichte, 1925, vol. 58, p. 1133

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(N-acetyl-anilino)-3-anilino-[1,4]naphthoquinone 在 氢氧化钾 作用下， 生成 2,3-bis(phenylamino)naphthalene-1,4-dione
  参考文献：
  名称：

  Fries; Billig, Chemische Berichte, 1925, vol. 58, p. 1133

  摘要：

  DOI：

文献信息

• [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium/1,1′-Bis(diphenylphosphino)ferrocene Catalyzed Synthesis of 2,3-Diamino-1,4-naphthoquinones
  作者：John Reiner、Jun Chang、Xiao Wang、Xiu Zheng、Lei Wang、Wei Xie

  DOI：10.1055/s-2007-965983

  日期：2007.4

  coupling of 2-amino-3-chloro-1,4-naphthoquinones with amines is described. The scope and limitations of the coupling process using [1,1 '-bis(diphenylphosphino)ferrocene] dichloropalladium [PdCl 2 (dppf)], combined with 1,1'-bis(diphenylphosphino)ferrocene (dppf) as a ligand and sodium tert-butoxide as base were investigated, and found to catalyze efficiently the coupling of 2-(arylamino)-3-chloro- 1,4-naphthoquinones

  描述了一种通过 2-氨基-3-氯-1,4-萘醌与胺的钯催化偶联合成 2,3-二氨基-1,4-萘醌衍生物的一般方法。使用[1,1'-双(二苯基膦基)二茂铁]二氯钯[PdCl 2 (dppf)]与1,1'-双(二苯基膦基)二茂铁(dppf)作为配体和钠的偶联过程的范围和限制对作为碱的叔丁醇进行了研究，发现它可以有效地催化 2-(芳基氨基)-3-氯-1,4-萘醌与伯芳基胺和烷基胺的偶联。应用该程序获得了一系列以前无法获得的新型2,3-二氨基-1,4-萘醌衍生物。
• Synthesis of novel substituted naphthoquino[b]-benzo[e][1,4]diazepines via Pictet–Spengler cyclization
  作者：Xiao Lei Wang、Xiu Fang Zheng、Ren He Liu、John Reiner、Jun Biao Chang

  DOI：10.1016/j.tet.2007.02.002

  日期：2007.4

  Synthesis of novel 4,5-dihydro-1H-1,4-naphthoquino[b]-benzo[e][1,4]diazepine derivatives via Pictet–Spengler cyclization is reported. Reaction of 2,3-diamino-naphthoquinones with aldehydes in the presence of BF3·Et2O gives benzodiazepine-naphthoquinones in good yields.

  据报道，通过Pictet-Spengler环化反应合成了新的4,5-二氢-1 H -1,4-萘喹[ b ]-苯并[ e ] [1,4]二氮杂卓衍生物。在BF 3 ·Et 2 O的存在下2,3-二氨基萘醌与醛的反应可得到高产率的苯并二氮杂萘醌。
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Thiosemicarbazides, Potent Reagents for Synthesis of Some New 1,4-Diphenylbenzo[g]quinoxaline-5,10-dione Based Heterocycles
  作者：Islam H. El Azab、Hosam A. Saad

  DOI：10.3987/com-16-13512

  日期：——

  2-(5,10-Dioxo-1,4-dipheny1-3,4-dihydrobenzo[g]quinoxalin-2(1H,5H, 10H)-ylidenOhydrazinecarbothioamide (4) and 244-oxothiazolidin-2-ylidene)hydrazono)-1,4-dipheny1-1,2,3,4-tetrahydrobenzo[g]quinoxaline-5,10-dione (5), were prepared and utilized as versatile building blocks, via incorporating in series of conversions including cyclocondensation reactions to afford a series of four and five pharmacophoric motif conjugates 10, 13, 18, 20, 21, 25, 30, 31, 32, 33 and 34 in fair yields.
• US4757124A
  申请人：——

  公开号：US4757124A

  公开（公告）日：1988-07-12