2-(7-氨基庚基氨基)乙醇 | 62578-25-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2-(7-氨基庚基氨基)乙醇
• 英文名称: 2-(7-amino-heptylamino)-ethanol
• 英文别名: 2-(7-Amino-heptylamino)-aethanol；2-[(7-Aminoheptyl)amino]ethan-1-ol；2-(7-aminoheptylamino)ethanol
• CAS: 62578-25-0
• 化学式: C₉H₂₂N₂O
• 分子量: 174.286
• InChiKey: JLOABVOYQJTWDV-UHFFFAOYSA-N

物化性质

• 沸点：
  164-168 °C(Press: 1 Torr)
• 密度：
  0.931±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  58.3
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(7-氨基庚基氨基)乙醇 、 9-氯-2,3-二甲氧基-6-硝基吖啶 在 苯酚 作用下， 生成 2-[7-(2,3-dimethoxy-6-nitro-acridin-9-ylamino)-heptylamino]-ethanol
  参考文献：
  名称：

  Steck et al., Journal of the American Chemical Society, 1957, vol. 79, p. 4414,4417

  摘要：

  DOI：
• 作为产物：
  描述：

  7-氨基庚腈 在 吡啶 、 lithium aluminium tetrahydride 作用下， 生成 2-(7-氨基庚基氨基)乙醇
  参考文献：
  名称：

  N,N'-Heptamethylenebis(4-methoxybenzamide)

  摘要：

  4-(Q-O)-4'-R.sub.1 -N,N'-烷基亚苯二酰胺，N,N'-烷基亚苯二酰胺或N,N'-烷基亚苯二酰胺[4-(较低烷氧基)苯二酰胺]，具有内分泌学性质，其中Q为较低烷基，较低烷氧基烷基，较低烯基，卤代较低烷基，卤代较低烯基，较低环烷基，苯基和BN-(较低烷基)，其中BN为二(较低烷基)氨基或具有五至七个环原子的饱和N-杂环烷基基团，烷基在其两个连接链之间至少有五个碳原子，R.sub.1为Q-O-，氢，较低烷氧基，较低烷基，卤素，苄氧基，羟基，二(较低烷基)氨基，硝基，氨基或三卤甲基，最好通过将适当的二胺或N-(氨基烷基)-苯二酰胺与相应的苯甲酰卤反应制备两个或一个摩尔当量。

  公开号：

  US04009208A1

文献信息

• 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
  申请人：Almirall, S.A.

  公开号：EP2394998A1

  公开（公告）日：2011-12-14

  New pyridazin-3(2H)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the phosphodiesterase IV (PDE4).

  新的吡啶并嗪-3(2H)-酮衍生物具有化学结构的公式(I)；以及它们的制备方法、包含它们的药物组合物以及它们作为磷酸二酯酶IV（PDE4）抑制剂在治疗中的用途。
• 2, 3-alkylenedioxy-6-nitro-9-(hydroxy-alkylaminoalkylamino) acridines and their preparation
  申请人：STERLING DRUG INC

  公开号：US02762809A1

  公开（公告）日：1956-09-11
• Oxazolidines derived from polyalkyl or polyalkenyl n-hydroxyalkyl succinimides, obtainment process and use
  申请人：Zamudio Rivera Luis Silvestre

  公开号：US20100107478A1

  公开（公告）日：2010-05-06

  The present invention relates to oxazolidines derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides, the obtainment process thereof, and their use to prevent and control the formation of deposits in internal combustion engines, primarily in formulations of additives to be applied to hydrocarbon fuels. The oxazolidines derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides of the present invention, have the structural formula wherein: R is a polyalkyl or polyalkenyl group having an average molecular weight ranging from 450 to 5000 daltons; m is an integer between 1 and 5; n is an integer between 0 and 1; and R 1 , R 2 , R 3 , and R 4 are independent radicals, represented by the groups: —H, —CH 2 (CH 2 ) A B, —C 6 H 3 DE or —C 10 H 4 FG; wherein: A is an integer between 0 and 8, B is a group selected among —H, —NH 2 , —OH, —COOH, and D, E, F, and G are independent radicals, selected among the groups: —H, —CH 3 , —CH 2 CH 3 , —CH 2 CH 2 CH 3 , —CH 2 (CH 2 ) 2 CH 3 , —(CH 3 ) 3 , C 6 H 5 , —NH 2 , —OH, —OCH 3 , OCH 2 CH 2 OH, OCH(CH 3 )CH 2 OH, OC 6 H 5 —COOH, —SO 3 .
• Formulations comprising an asphaltene-dispersing/inhibiting additive based on oxazolidines derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides
  申请人：Mena Cervantes Violeta Yasmin

  公开号：US20110162558A1

  公开（公告）日：2011-07-07

  The present invention relates to formulations of asphaltenes' inhibitor-dispersant additives based on oxazolidine derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides. Said formulations can contain inert organic solvents, preferably including: toluene, mixtures of xylene, o-xylene, p-xylene, kerosene, turbo-fuel; or inert hydrocarbon solvents having boiling points within the range of gasoline and diesel; or inert hydrocarbon or organic solvents having a boiling point within a range from 75 to 300° C. The ratio in weight of inert organic solvents to additive that prevents and controls the precipitation and deposition of asphaltenes ranges from 1:9 to 9:1, preferably from 1:3 to 3:1.
• US4009208A
  申请人：——

  公开号：US4009208A

  公开（公告）日：1977-02-22