1-[2'-(3H-inden-1"-yl)ethyl]-5-(4"'-vinylphenyl)-3H-indene | 848760-82-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚和异茚
• 英文名称: 1-[2'-(3H-inden-1"-yl)ethyl]-5-(4"'-vinylphenyl)-3H-indene
• 英文别名: 1H-Indene, 6-(4-ethenylphenyl)-3-[2-(1H-inden-3-yl)ethyl]-；6-(4-ethenylphenyl)-3-[2-(3H-inden-1-yl)ethyl]-1H-indene
• CAS: 848760-82-7
• 化学式: C₂₈H₂₄
• 分子量: 360.499
• InChiKey: LIRGOGCBVGLARZ-UHFFFAOYSA-N

物化性质

• 沸点：
  545.9±50.0 °C(Predicted)
• 密度：
  1.111±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  5-溴茚酮 在 四(三苯基膦)钯 lithium aluminium tetrahydride 、 正丁基锂 、 potassium carbonate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 24.0h， 生成 1-[2'-(3H-inden-1"-yl)ethyl]-5-(4"'-vinylphenyl)-3H-indene
  参考文献：
  名称：

  Selective alkylation and Suzuki coupling as an efficient strategy for introducing functional anchors to the ethylene-bis(indenyl) ligand

  摘要：

  Chiral ansa-ethylene-bis(indenyl)-metal complexes, EBI-MX2, are useful pre-catalysts for a wide variety of reactions, including hydrogenations, hydrosilylations, and polymerization reactions. In order to immobilize these complexes onto heterogeneous supports, a new methodology was developed to introduce functional anchors to the ethylene-bis(indenyl) ligand, EBI. This was accomplished by selective alkylation of indene to form toluene-4-sulfonic acid 2-(3H-inden-1-y1)-ethyl ester, which was then used to alkylate 6-bromoindene. The selective introduction of an aryl bromide then undergoes coupling reactions with aryl borates via the Suzuki coupling to efficiently introduce an alkenyl or alcohol, functional anchor in a simple four step synthesis. (C) 2005 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2004.12.101

文献信息

• Selective alkylation and Suzuki coupling as an efficient strategy for introducing functional anchors to the ethylene-bis(indenyl) ligand
  作者：Anthony P. Panarello、Oleksiy Vassylyev、Johannes G. Khinast

  DOI：10.1016/j.tetlet.2004.12.101

  日期：2005.2

  Chiral ansa-ethylene-bis(indenyl)-metal complexes, EBI-MX2, are useful pre-catalysts for a wide variety of reactions, including hydrogenations, hydrosilylations, and polymerization reactions. In order to immobilize these complexes onto heterogeneous supports, a new methodology was developed to introduce functional anchors to the ethylene-bis(indenyl) ligand, EBI. This was accomplished by selective alkylation of indene to form toluene-4-sulfonic acid 2-(3H-inden-1-y1)-ethyl ester, which was then used to alkylate 6-bromoindene. The selective introduction of an aryl bromide then undergoes coupling reactions with aryl borates via the Suzuki coupling to efficiently introduce an alkenyl or alcohol, functional anchor in a simple four step synthesis. (C) 2005 Published by Elsevier Ltd.