1,4,7,10,13-pentaoxacyclohexadecane-14,16-dione | 58484-45-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 1,4,7,10,13-pentaoxacyclohexadecane-14,16-dione
• CAS: 58484-45-0
• 化学式: C₁₁H₁₈O₇
• 分子量: 262.26
• InChiKey: WGKVQTHJQOWYFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  1,4,7,10,13-pentaoxacyclohexadecane-14,16-dione 在 4-乙酰氨基苯磺酰叠氮 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 二氯甲烷 为溶剂， 以92%的产率得到15-diazo-1,4,7,10,13-pentaoxacyclohexadecane-14,16-dione
  参考文献：
  名称：

  Reactions of macrocyclic rhodium carbenoids: regioselective synthesis of indol-3-yl macrocyclic lactones and cryptands

  摘要：

  A wide variety of new macrocyclic diazocarbonyl compounds with various spacers was synthesized. Macrocyclic rhodium(H) carberioid insertion with various substituted indoles was performed to afford regioselectively, indol-3-yl macrocyclic di- or tetralactones (C3-alkylation). Double carberioid insertion was also performed to afford indolyl cryptand molecules. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.102
• 作为产物：
  描述：

  三缩四乙二醇 、 丙二酰氯 在 二正丁基氧化锡 作用下， 生成 1,4,7,10,13-pentaoxacyclohexadecane-14,16-dione
  参考文献：
  名称：

  使用二丁基锡氧化物从具有二酸氯化物的乙二醇制备大环二-或四酯/醚化合物

  摘要：

  通过使用二丁基氧化锡，通过各种低聚乙二醇与脂族和芳族二酰氯反应，以及含杂原子的二甘醇与己二酰氯反应，可以容易地制备几种大环二酯或四酯/醚化合物，收率良好。

  DOI：

  10.1246/cl.1984.1985

文献信息

• 一种冠醚快速合成方法
  申请人：浙江肯特催化材料科技有限公司

  公开号：CN107915716A

  公开（公告）日：2018-04-17

  本发明公开了一种冠醚快速合成方法，主要通过草酰氯、丙二酸、聚乙二醇和甲苯加热反应，再进行后续处理可得到成品，步骤如下：1）草酰氯与丙二酸反应，常温下搅拌，制备丙二酰氯；2）将丙二酰氯、聚乙二醇和甲苯在容器中常温混合；3）流经夹套管道，夹套用水蒸气加热，并控制反应物在管道内停留时间，收集流出的反应液；4）流出的反应液通过蒸馏、萃取、重结晶等步骤后，可得到白色针状晶体。本发明合成方法工艺简单、反应时间极短、产率有所提高，并能够通过不同聚乙二醇作为反应物，得到不同的冠醚。
• Catalysis with inorganic cations. VIII. Macrocyclic-yliden malonates: Synthesis, spectroscopic investigation, and metal perchlorate catalysis of the Diels-Alder reaction
  作者：Giovanni Desimoni、Giuseppe Faita、Marina Ricci、PierPaolo Righetti

  DOI：10.1016/s0040-4020(98)00517-1

  日期：1998.8

  Macrocyclic-yliden malonates 8–10 have been prepared by Knoevenagel condensation of differently sized crown malonates 5–7 with several aldehydes. The spectroscopic investigations of derivatives 8–10a in several solvents (acetone, acetonitrile, and dichloromethane) in the presence of sodium, lithium, barium, and magnesium perchlorate, evidenced, in some cases, the formation of different complexes, whose

  大环基丙二酸酯8-10是通过Knoevenagel将不同大小的冠状丙二酸酯5-7与几种醛缩合而制得的。在存在钠，锂，钡和高氯酸镁的情况下，在几种溶剂（丙酮，乙腈和二氯甲烷）中对衍生物8-10a进行的光谱研究表明，在某些情况下会形成不同的配合物，其结构取决于阳离子和冠醚单元的尺寸。9-10的Mg（II）络合物涉及两个羰基氧原子，这种特定的相互作用对9-10b与环戊二烯之间的Diels-Alder反应具有很强的催化作用。
• Coating varnish composition and antifouling coating composition
  申请人：HITACHI CHEMICAL CO., LTD.

  公开号：EP0608132A1

  公开（公告）日：1994-07-27

  The invention provides a coating varnish composition comprising (A) a polymer obtained by polymerizing (a) at least one unsaturated acid anhydride and (b) at least one other unsaturated monomer, and (B) at least one additive selected from triazole derivatives, benzothiazole derivatives, thiadiazole derivatives, polyethers and carboxylic acid anhydride derivatives and an antifouling coating composition comprising said coating varnish and an antifouling agent containing a coppercompound as major component. Using such compositions the risks of poisoning associated with organotin copolymers are avoided and there are obtained coatings of a coating consuming property and antifouling performance comparable with those of the organotin copolymers which do not gel even when mixed with a copper compound.

  本发明提供了一种涂料清漆组合物，该组合物包含(A)通过聚合(a)至少一种不饱和酸酐和(b)至少一种其他不饱和单体而得到的聚合物，和(B)至少一种选自三唑衍生物、苯并噻唑衍生物、噻二唑衍生物、聚醚和羧酸酐衍生物的添加剂，以及一种防污涂料组合物，该组合物包含上述涂料清漆和一种以铜化合物为主要成分的防污剂。使用这种组合物可以避免与有机锡共聚物有关的中毒风险，并获得涂层消耗特性和防污性能与有机锡共聚物相当的涂层，即使与铜化合物混合也不会凝胶。
• Selective Syntheses of Novel Polyether Fullerene Multiple Adducts
  作者：Zhiguo Zhou、David I. Schuster、Stephen R. Wilson

  DOI：10.1021/jo034542l

  日期：2003.10.1

  We have applied a modified macrocyclic tether approach to control multiple additions to C-60. The technique of He-3 NMR was used to confirm the selective formation of specific C-60 multiple adducts by the macrocyclic tether approach. An oligoglycol was used as a flexible linker to produce macrocyclic polyether-linked malonates 5, 6, 8, and 9 under solid-liquid PTC (phase-transfer-catalysis) conditions. The formation of a single C60 tris-adduct, 3, from macrocyclic malonate 1 and (HeC60)-He-3-C-@ was proven by He-3 NMR. Similarly, multiple additions to C-60 of macrocyclic polyether malonate 5 gave C-60 bis-adduct 10 selectively, while the reaction of C-60 with macrocyclic malonate 8 gave bis-adducts 11 and 12. A similar process with macrocyclic malonate 6 gave tris-adduct 13 with high selectivity as well. Saponification of these C-60 multiple adducts gives the corresponding polyacids that are potentially useful in biological applications. Macrocyclic polyether fullerenes are a new class of ionophores, which could be interesting for molecular recognition and for the development of biosensors.
• Cyclopolymers as Liquid Membrane Carriers
  作者：Emanuela Cagnoni、Dario Pasini、Alessandro Galbiati、Marina Ricci、Righetti

  DOI：10.1021/ma034901e

  日期：2003.11.1