bis-diethylamino-difluoromethane | 134329-17-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: bis-diethylamino-difluoromethane
• 英文别名: N,N,N',N'-tetraethyl-1,1-difluoromethanediamine
• CAS: 134329-17-2
• 化学式: C₉H₂₀F₂N₂
• 分子量: 194.268
• InChiKey: IQYKTDZMKYQWRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  bis-diethylamino-difluoromethane 在 仲丁醇 作用下， 以 乙醚 为溶剂， 反应 3.5h， 生成 C,C-bis(diethylamino)methylenephosphine
  参考文献：
  名称：

  Povolotskii, M. I.; Negrebetskii, V. V.; Romanenko, V. D., Journal of general chemistry of the USSR, 1990, vol. 60, # 10.1, p. 2000 - 2005

  摘要：

  DOI：

文献信息

• Process for producing alpha, alpha-difluorocycloalkane compound
  申请人：——

  公开号：US20030078460A1

  公开（公告）日：2003-04-24

  A method for producing an &agr;,&agr;-difluorocycloalkane at high purity with good efficiency, which comprises a step of treating a fluorocycloalkene with hydrogen fluoride wherein the fluorocycloalkene has one fluorine atom directly bonded to a carbon atom of carbon-carbon unsaturated double bond, more preferably, a step of directly adding the hydrogen fluoride to a reaction mixture obtained by treating the cycloalkanone with the de-oxygen fluorinating agent.

  一种用高纯度和良好效率生产α，α-二氟环烷烃的方法，包括处理氟环烷烯与氢氟酸的步骤，其中氟环烷烯的一个氟原子直接连接到碳-碳不饱和双键的碳原子，更优选地，直接将氢氟酸添加到通过用脱氧氟化剂处理环戊酮得到的反应混合物的步骤。
• Halogenating agents
  申请人：——

  公开号：US20030004348A1

  公开（公告）日：2003-01-02

  Disclosed are a fluorinating agent represented by the general formula (1): 1 wherein R 1 to R 4 are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group, and can be the same or different; R 1 and R 2 or R 3 and R 4 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms; or R 1 and R 3 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms, for example: 2 a preparation process of the fluorinating agent and a process for preparing fluorine compounds by reacting various compounds with the fluorinating agent. The invention has also disclosed that the fluorinating agent is very effective for fluorinating oxygen containing functional compounds.

  本发明涉及一种由一般式（1）表示的氟化剂：其中R1至R4是取代或未取代的饱和或不饱和烷基或取代或未取代的芳基，可以相同也可以不同；R1和R2或R3和R4可以结合形成包括氮原子或氮原子和其他杂原子的环；或者R1和R3可以结合形成包括氮原子或氮原子和其他杂原子的环，例如：2。本发明还公开了上述氟化剂的制备方法以及通过将各种化合物与氟化剂反应制备氟化合物的方法。本发明还揭示了该氟化剂对于氧含量的功能性化合物氟化非常有效。
• Nitrogen-based halogenating agents and process for preparing halogen-containing compounds
  申请人：——

  公开号：US20020042521A1

  公开（公告）日：2002-04-11

  Disclosed are a fluorinating agent represented by the general formula (1): 1 wherein R 1 to R 4 are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group, and can be the same or different; R 1 and R 2 or R 3 and R 4 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms; or R 1 and R 3 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms, for example: 2 a preparation process of the fluorinating agent and a process for preparing fluorine compounds by reacting various compounds with the fluorinating agent. The invention has also disclosed that the fluorinating agent is very effective for fluorinating oxygen containing functional compounds.

  本发明涉及的是一种通式（1）所表示的氟化剂： 其中，R1至R4为取代或未取代的饱和或不饱和烷基或取代或未取代的芳基，可以相同也可以不同；R1和R2或R3和R4可以结合形成一个环，包括一个氮原子或一个氮原子和其他杂原子；或者R1和R3可以结合形成一个环，包括一个氮原子或一个氮原子和其他杂原子，例如： 本发明还揭示了该氟化剂对于氧含有官能团的化合物的氟化非常有效。同时，本发明还揭示了该氟化剂的制备方法和通过将各种化合物与该氟化剂反应制备氟化合物的方法。
• Halogenating agent
  申请人：Mitsui Chemicals, Inc.

  公开号：EP0895991A2

  公开（公告）日：1999-02-10

  wherein R1 to R4 are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group, and can be the same or different ; R1 and R2 or R3 and R4 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms ; or R1 and R3 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms, for example : a preparation process of the fluorinating agent and a process for preparing fluorine compounds by reacting various compounds with the fluorinating agent. The invention has also disclosed that the fluorinating agent is very effective for fluorinating oxygen containing functional compounds.

  其中 R1 至 R4 是取代或未取代的饱和或不饱和烷基或取代或未取代的芳基，可以相同或不同；R1 和 R2 或 R3 和 R4 可以键合形成包括氮原子或氮原子和其他杂原子的环；或 R1 和 R3 可以键合形成包括氮原子或氮原子和其他杂原子的环，例如......： 氟化剂的制备工艺，以及通过各种化合物与氟化剂反应制备氟化合物的工艺。本发明还公开了氟化剂对含氧功能化合物的氟化非常有效。
• Process for the preparation of acetylene derivatives
  申请人：Mitsui Chemicals, Inc.

  公开号：EP0949226A1

  公开（公告）日：1999-10-13

  Disclosed is a preparation process of an acetylene derivative comprising reacting a compound having a skeleton represented by the formula (1) : in the molecular formula with a compound represented by the formula (2) : wherein R1, R2, R3 and R4 are each a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group, for instance having 1 to 6 carbon atoms, and can be the same or different, R1 and R2 or R3 and R4 can bond to form a ring including a nitrogen atom or nitrogen atom and other hetero atoms; or R1 and R3 can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms; or with a compound represented by the formula (3): wherein R1, R2, R3 and R4 are the same as in the formula (2), and X1 is a chlorine, bromine or iodine atom.

  本发明公开了一种炔衍生物的制备工艺，该工艺包括使分子式为式（1）...的化合物与分子式为式（2）...的化合物反应： 分子式中，R1、R2、R3 和 R4 分别是取代或未取代的饱和烷基： 其中R1、R2、R3和R4各自为取代或未取代的饱和或不饱和烷基或取代或未取代的芳基，例如具有1至6个碳原子，可以相同或不同，R1和R2或R3和R4可以键合形成包括氮原子或氮原子和其它杂原子的环；或R1和R3可以键合形成包括氮原子或氮原子和其它杂原子的环；或与式(3)代表的化合物反应： 其中 R1、R2、R3 和 R4 与式（2）中的相同，X1 是 氯、溴或碘原子。