2-butoxybenzoic acid butyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-butoxybenzoic acid butyl ester
• 英文别名: Salicylic acid, butyl ether, butyl ester；butyl 2-butoxybenzoate
• 化学式: C₁₅H₂₂O₃
• 分子量: 250.338
• InChiKey: RSCOHALZSFTTRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-甲氧基苯甲酸甲酯 、 sodium butanolate 、 N,N-二甲基甲酰胺 以67%的产率得到
  参考文献：
  名称：

  Hattori Tetsutaro, Satoh Seiichi, Miyano Sotaro, Bull. Chem. Soc. Jap., 66 (1993) N 12, S 3840-3842

  摘要：

  DOI：

文献信息

• SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND
  申请人：RNS CO.,LTD.

  公开号：US20160221921A1

  公开（公告）日：2016-08-04

  Provided is a derivative or a polyhydroxy cyclic compound represented by Formula I or a pharmacologically acceptable salt thereof with excellent whitening effects, comprising; wherein circle around (A)} is derived from an aromatic cyclic compound, B is hydrogen, oxo (═O), amino (—NH 2 ), imino (═NH), or a saturated or unsaturated straight or branched alkyl, alkoxy, monoalkylamino, or dialkylamino group having 1 to 10 carbon atoms, C n , C n+1 and C n+2 are three neighboring carbon atoms present in the aromatic cyclic compound, wherein n is a positive integer, R 1 is hydrogen, hydroxy, or a saturated or unsaturated straight or branched alkyl or alkoxy group, X and Y are selected from a group consisting of hydrogen, hydroxy, and a saturated or unsaturated straight or branched alkoxy, or acyloxy group, and one of X and Y is hydrogen, R 2 , R 3 , R 4 and R 5 are each independently at least one substituent selected from a group consisting of hydrogen, alkyl, alkoxy, acyloxy, acyloxymethyl, oxo, hydroxy, vinyl, nitrile, carboxaldehyde, carbonitrile and aldehyde.

  提供的是一种由化学式I表示的衍生物或多羟基环化合物，或其药理学上可接受的盐，具有出色的美白效果，包括；其中圆圈A}源自芳香环化合物，B为氢、氧化物(═O)、氨基(—NH2)、亚胺基(═NH)或具有1至10个碳原子的饱和或不饱和直链或支链烷基、烷氧基、单烷基氨基或二烷基氨基基团，Cn、Cn+1和Cn+2是芳香环化合物中存在的三个相邻碳原子，其中n为正整数，R1为氢、羟基或饱和或不饱和直链或支链烷基或烷氧基，X和Y从氢、羟基和饱和或不饱和直链或支链烷氧基或酰氧基组成的一组中选择，并且X和Y中的一个为氢，R2、R3、R4和R5分别独立地至少为来自氢、烷基、烷氧基、酰氧基、酰氧甲基、氧化物、羟基、乙烯基、腈基、羧醛基、碳腈基和醛基的取代基组成的一组中的至少一种取代基。
• Facile Alkoxyl Exchange of 2-Methoxybenzoates via Nucleophilic Aromatic Substitution with Sodium Alkoxides in Dimethylformamide
  作者：Tetsutaro Hattori、Seiichi Satoh、Sotaro Miyano

  DOI：10.1246/bcsj.66.3840

  日期：1993.12

  Methyl 2-methoxybenzoate undergoes facile nuclear-methoxyl displacement by treatment with sodium butoxide or isopropoxide in dimethylformamide.

  通过在二甲基甲酰胺中用丁醇钠或异丙醇处理，2-甲氧基苯甲酸甲酯可以轻松地进行核甲氧基置换。
• Fingerprinting compositions, systems and methods
  申请人：Vassiliades, Anthony E.

  公开号：EP0330770A1

  公开（公告）日：1989-09-06

  A self-contained liquid composition for use in making fingerprints, comprising the reaction product of at least one leuco or non-leuco chromogenic compound and at least one colour-developing substance in a liquid vehicle that is a solvent for the chromogenic compound and reaction product and a solvent or dispersant for the colour-developing substance.

  一种用于制作指纹的独立液体组合物，它包含至少一种发色或非发色化合物和至少一种显色物质在液体载体中的反应产物，液体载体是发色化合物和反应产物的溶剂，也是显色物质的溶剂或分散剂。
• A cycloalkene compound and a recording material using the compound
  申请人：HODOGAYA CHEMICAL COMPANY, LIMITED

  公开号：EP0364120A2

  公开（公告）日：1990-04-18

  A cycloalkene compound of the general formula [1]: wherein R¹ and R² each is C₁-C₄ alkyl, R³ is hydrogen or C₁-C₄ alkyl, R⁴ and R⁵ together represent -CH₂-CH₂- or -CH₂-CH₂-CH₂-, and R⁶ is C₁-C₄ alkyl is useful as a color former in a recording material.

  通式[1]的环烯化合物： 其中 R¹ 和 R² 各为 C₁-C₄ 烷基，R³ 为氢或 C₁-C₄ 烷基，R⁴ 和 R⁵ 共同代表 -CH₂-CH₂- 或 -CH₂-CH₂-CH₂- 、和 R⁶ 是 C₁-C₄ 烷基，可用作记录材料中的显色剂。
• Compounds and therapies for the prevention of vascular and non-vascular pathologies
  申请人：NeoRx Corporation

  公开号：US20030064970A1

  公开（公告）日：2003-04-03

  The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.

  本发明提供了一种治疗哺乳动物的方法，该哺乳动物具有或有可能具有与 TGF-beta 缺乏有关的适应症，该方法包括施用一种或多种能有效提高 TGF-beta 水平的制剂。本发明还提供了能提高TGF-beta水平的新型化合物、包含能提高TGF-beta水平的化合物的药物组合物，以及检测与内皮细胞活化相关的疾病的方法。