3-(N-ethyl-m-tolueneamino)propionic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(N-ethyl-m-tolueneamino)propionic acid
• 英文别名: N-ethyl-N-(3-methylphenyl)-beta-alanine；3-(N-ethyl-3-methylanilino)propanoic acid
• 化学式: C₁₂H₁₇NO₂
• 分子量: 207.272
• InChiKey: ZNTIXLHQPKPOBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-甲基-4-氨基邻苯二甲酰亚胺 、 3-(N-ethyl-m-tolueneamino)propionic acid 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以89.8%的产率得到
  参考文献：
  名称：

  含邻苯二甲酰亚胺结构的偶合组分及其制备方法和应用

  摘要：

  本发明公开了一种含邻苯二甲酰亚胺结构的偶合组分及其制备方法和应用，结构式如式(11)‑(13)所示。本发明所制备的含邻苯二甲酰亚胺结构的偶合组分，属于新型的含邻苯二甲酰亚胺的偶合组分，通过连接邻苯二甲酰亚胺苯环上的取代基，从而引入邻苯二甲酰亚胺结构，酰亚胺的氮原子可以连接不同的取代基R1，使染料具有不同的应用性能，表现出优异的水洗色牢度。同时涤纶织物染后可仅使用碱洗工艺，避免了保险粉还原清洗条件下偶氮基被分解产生致癌芳香胺释放到污水，降低了洗涤污水处理负担，具有高环保性能。

  公开号：

  CN111303005B

文献信息

• OXIDATIVE CHROMOGENIC COMPOUND OR SALT THEREOF AND PRODUCTION METHOD THEREOF, AND REAGENT COMPOSITION AND TEST INSTRUMENT USING THE SAME
  申请人：Kawanishi Tetsuro

  公开号：US20100062464A1

  公开（公告）日：2010-03-11

  It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R 1 and R 2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R 3 , R 4 , R 5 , R 6 and R 7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R 3 to R 7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.

  本发明的目的是提供一种快速、高精度和高灵敏度测量各种成分浓度的手段。本发明提供了一种氧化性显色化合物或其盐，其化学式如下（1）：其中R1和R2分别是具有1至5个碳原子的线性或支链烷基；R3、R4、R5、R6和R7分别是氢原子、羧基或磺酸基，或其盐，但至少其中之一是羧基或磺酸基，或其盐，其余为氢原子，以及其生产方法、试剂组成和使用该试剂组成的测试仪器。
• Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin
  申请人：Kaminuma Mikiko

  公开号：US20120232111A1

  公开（公告）日：2012-09-13

  The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin—inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and further provides an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent comprises one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof. The external composition for skin comprises the one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent.

  本发明提供了一种角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂，具有诸如角化过度抑制、毛孔收缩或粗糙肌肤抑制/减轻等功能，不会引起感觉刺激等安全问题，非常安全，还提供了一种外用皮肤组成物，其中添加了具有上述功能的化合物。该角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂包括从β-丙氨酸衍生物和其盐的群组中选择的一种或多种化合物。该外用皮肤组成物包括上述β-丙氨酸衍生物和其盐中的一种或多种作为上述角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂。
• Multizone element and method for analysis of whole blood
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0140337A2

  公开（公告）日：1985-05-08

  A multizone element and method are designed for use for the determination of an analyte in whole blood. In particular, this element and method is useful for the quantitative determination of peroxide-generating analytes, such as glucose or cholesterol, in whole blood. The multizone element has a support having thereon, in order and in fluid contact, a registration zone and a reagent/spreading zone but excludes a whole blood cell filter zone. The reagent/spreading zone has a void volume and average pore size effective to accomodate whole blood, and contains an interactive composition necessary for the analysis. Such composition is capable of providing, upon interaction with the analyte, a dye which can be spectrophotometrically detected at a wavelength greater than or equal to 600 nm.

  一种多区元件和方法设计用于测定全血中的被分析物。 特别是，这种元件和方法可用于定量测定全血中产生过氧化物的被分析物，如葡萄糖或胆固醇。 多区元件有一个支撑物，其上依次有一个登记区和一个试剂/扩散区，但不包括一个全血细胞过滤区。 试剂/扩散区的空隙体积和平均孔径可有效容纳全血，并含有分析所需的交互组合物。 这种组合物在与被分析物交互作用时能够提供一种染料，该染料可在大于或等于 600 纳米的波长下进行分光光度检测。
• Test devices for determination of occult blood and glucose
  申请人：MILES INC.

  公开号：EP0316762A1

  公开（公告）日：1989-05-24

  Test device is useful for determining glucose or occult blood comprising a carrier matrix, glucose oxidase, an indicator system and a glucose derivative that upon addition of water hydrolizes to produce glucose.

  测试装置可用于测定葡萄糖或隐血，包括载体基质、葡萄糖氧化酶、指示系统和葡萄糖衍生物，该衍生物在加水后水解生成葡萄糖。
• Method of selectively measuring triglycerides
  申请人：Okada Masahiko

  公开号：US20050255536A1

  公开（公告）日：2005-11-17

  The present invention relates to a reagent for selective measurement of triglycerides contained in very low density lipoprotein and intermediate density lipoprotein or in very low density lipoprotein in a test sample, including a first reagent that contains a first selective reaction promoter, which is an ether or ester compound of a polyoxyalkylene capable of reacting lipoprotein lipase selectively with triglycerides contained in low density lipoprotein and high density lipoprotein; lipoprotein lipase; enzymes which catalyze a series of reactions leading to the generation of hydrogen peroxide or a reduced coenzyme from glycerol; and an enzyme which catalyzes a reaction leading to the conversion of hydrogen peroxide or a reduced coenzyme into another substance, and a second reagent that contains a second selective reaction promoter, which is capable of reacting lipoprotein lipase selectively with triglycerides contained in very low density lipoprotein, intermediate density lipoprotein, low density lipoprotein and high density lipoprotein and to a method for selective measurement of triglycerides contained in very low density lipoprotein and intermediate density lipoprotein or in very low density lipoprotein in a test sample which uses the above reagent.

  本发明涉及一种用于选择性测量极低密度脂蛋白和中密度脂蛋白或测试样品中极低密度脂蛋白所含甘油三酯的试剂，包括含有第一选择性反应促进剂的第一试剂，该促进剂是聚氧亚烷基的醚或酯化合物，能够使脂蛋白脂肪酶选择性地与低密度脂蛋白和高密度脂蛋白中所含的甘油三酯反应；脂蛋白脂肪酶； 能催化一系列反应，导致从甘油中生成过氧化氢或还原型辅酶的酶；和催化导致过氧化氢或还原型辅酶转化为另一种物质的反应的酶，以及含有第二种选择性反应促进剂的第二种试剂，该试剂能够使脂蛋白脂肪酶选择性地与极低密度脂蛋白中所含的甘油三酯反应、以及一种使用上述试剂选择性地测量测试样品中极低密度脂蛋白和中密度脂蛋白或极低密度脂蛋白所含甘油三酯的方法。