chloro-p-tolylglyoxime | 143962-59-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: chloro-p-tolylglyoxime
• 英文别名: C-hydroxyimino-C-p-tolyl-acetohydroximic acid-chloride；C-Hydroxyimino-C-p-tolyl-acetohydroximsaeure-chlorid；2-Chlor-1.2-dioximino-1-p-tolyl-aethan；α'-Chlor-α-p-tolyl-glyoxim；2-Hydroxyimino-2-p-tolyl-acetohydroximoylchlorid；p-Tolylchlorglyoxim；p-Tolylchloroglyoxime；N-hydroxy-2-hydroxyimino-2-(4-methylphenyl)ethanimidoyl chloride
• CAS: 143962-59-8
• 化学式: C₉H₉ClN₂O₂
• 分子量: 212.636
• InChiKey: FQHISBSQCXVINY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  65.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  chloro-p-tolylglyoxime 以 乙醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  Preparation and Spectral and Biological Investigation of vic-Dioxime Ligands Containing Piperazine Moiety and Their Mononuclear Transition-Metal Complexes

  摘要：

  Two vic-dioxime ligands, N-(4-benzylpiperazine-1-yl) p-tolylglyoxime ((LH2)-H-1) and N,N-bis(4-benzylpiperazine-1-yl) glyoxime ((LH2)-H-2), containing piperazine moieties were synthesized, and their Ni(II), Cu(II), Co(II) and Zn(II) complexes were obtained. The ligands were characterized by elemental analysis, Fourier transform-infrared (FT-IR), ultraviolet-visible NMR (H-1, C-13, and heteronuclear multiple-bond correlation), and electrospray ionization (ESI) mass spectrometry. The isolated complexes were characterized by a combination of elemental analysis, IR, UV-vis, and ESI mass spectrometry and in the case of Ni(II) and Zn(II) complexes by H-1 and C-13 NMR spectroscopy. The electrochemical behaviors of the ligands and their complexes were studied by cyclic voltammetry (CV) in dimethylsulfoxide solution containing tetrabutylammoniumtetrafluoroborate (TBATFB). The antibacterial activity was also studied against S. aureus ATCC 25923, S. aureus ATCC 29213, S. mutans RSHM 676, E. faecalis ATCC 29212, E. coli ATCC 25922, and P. aeruginosa ATCC 27853. The antimicrobial test results indicated that all the compounds have good antibacterial activity against P. auriginosa ATCC 27853 bacteria and were as effective as ampicilin. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resources: Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2013.777743
• 作为产物：
  描述：

  对甲基-2-氯乙酰苯 在 盐酸 、 乙醚 、 乙醇 、 盐酸羟胺 作用下， 生成 chloro-p-tolylglyoxime
  参考文献：
  名称：

  AMINO ALCOHOLS. XI.¹ ARYLGLYOXYLOHYDROXAMYL CHLORIDES²

  摘要：

  DOI：

  10.1021/jo01199a002

文献信息

• Durio, Gazzetta Chimica Italiana, 1933, vol. 63, p. 747,748
  作者：Durio

  DOI：——

  日期：——
• Ponzio, Gazzetta Chimica Italiana, 1931, vol. 61, p. 715,719
  作者：Ponzio

  DOI：——

  日期：——
• Ponzio, Gazzetta Chimica Italiana, 1931, vol. 61, p. 561,571
  作者：Ponzio

  DOI：——

  日期：——
• Carbone, Gazzetta Chimica Italiana, 1932, vol. 62, p. 428,430
  作者：Carbone

  DOI：——

  日期：——
• Ponzio, Gazzetta Chimica Italiana, 1925, vol. 55, p. 317
  作者：Ponzio

  DOI：——

  日期：——