5-oxy-indeno[1,2-b]quinoxalin-11-one | 6965-50-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 5-oxy-indeno[1,2-b]quinoxalin-11-one
• 英文别名: 11-Oxo-11H-indeno<1,2-b> chinoxalin-5-oxid；11-Oxo-11H-indeno<1,2b> chinoxalin-5-oxid；11h-Indeno[1,2-b]quinoxalin-11-one 5-oxide；5-oxidoindeno[1,2-b]quinoxalin-5-ium-11-one
• CAS: 6965-50-0
• 化学式: C₁₅H₈N₂O₂
• 分子量: 248.241
• InChiKey: VRRONBPXKBGDIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  11H-茚并[1,2-b]喹喔啉-11-酮 在 双氧水 作用下， 以 溶剂黄146 为溶剂， 反应 18.0h， 生成 5-oxy-indeno[1,2-b]quinoxalin-11-one
  参考文献：
  名称：

  Synthesis of some 11H-indeno[1,2-b]quinoxalin-11-ones

  摘要：

  Condensation of substituted o-phenylene diamines and ninhydrins gave the tide compounds. The substituent orientation in the products was determined by H-1 NMR analysis of the chemical shifts brought about by N5-oxidation. Reduction of the 8-nitro to 8-amino compound was achieved both with and without reduction of the carbonyl group. Nitration of the 8-carboxylic acid occurred in the 2-position.

  DOI：

  10.1016/s0040-4020(01)80184-8

文献信息

• Synthesis of some 11H-indeno[1,2-b]quinoxalin-11-ones
  作者：Leslie W Deady、José Desneves、Andrew C Ross

  DOI：10.1016/s0040-4020(01)80184-8

  日期：1993.1

  Condensation of substituted o-phenylene diamines and ninhydrins gave the tide compounds. The substituent orientation in the products was determined by H-1 NMR analysis of the chemical shifts brought about by N5-oxidation. Reduction of the 8-nitro to 8-amino compound was achieved both with and without reduction of the carbonyl group. Nitration of the 8-carboxylic acid occurred in the 2-position.