α-Pyrrolomethanphosphonsaeurediethylester | 51297-15-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: α-Pyrrolomethanphosphonsaeurediethylester
• 英文别名: Pyrrol-1-yl-methanphosphonsaeurediethylester；Diethyl [(1H-pyrrol-1-yl)methyl]phosphonate；1-(diethoxyphosphorylmethyl)pyrrole
• CAS: 51297-15-5
• 化学式: C₉H₁₆NO₃P
• 分子量: 217.205
• InChiKey: BPKGAASEONHMFO-UHFFFAOYSA-N

物化性质

• 沸点：
  86-87 °C(Press: 0.01 Torr)
• 密度：
  1.15±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  40.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  α-Pyrrolomethanphosphonsaeurediethylester 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 生成 1-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-1H-pyrrole
  参考文献：
  名称：

  Gross, H.; Beisert, S.; Costisella, B., Journal fur praktische Chemie (Leipzig 1954), 1981, vol. 323, # 6, p. 877 - 886

  摘要：

  DOI：
• 作为产物：
  描述：

  (Diallylamino)-methylphosphonsaure-diethylester 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 、 ruthenium trichloride 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 12.0h， 以60%的产率得到α-Pyrrolomethanphosphonsaeurediethylester
  参考文献：
  名称：

  Pyrrole synthesis using a tandem Grubbs’ carbene–RuCl3 catalytic system

  摘要：

  A straightforward pyrrole synthesis from diallylamines is developed by using a tandem catalyst system leading to ring-closing metathesis with the second generation Grubbs' catalyst (10%) followed by dehydrogenation in the presence of RuCl3 x H2O (2%). (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.044

文献信息

• Metal complexes useful in metathesis and other reactions
  申请人：Walter Francis

  公开号：US20050043541A1

  公开（公告）日：2005-02-24

  This invention provides metal complexes being useful as catalyst components in metathesis reactions and in reactions involving the transfer of an atom or group to an ethylenically or acetylenically unsaturated compound or another reactive substrate and, with respect to a sub-class thereof, for the polymerisation of α-olefins and optionally conjugated dienes, with high activity at moderate tempera-tures. It also provides methods for obtaining polymers with very narrow molecular weight distribution by means of a living reaction. It also provides methods for making said metal complexes and novel intermediates involved in such methods. It further provides derivatives of said metal complexes which are suitable for covalent bonding to a carrier, the product of such covalent bonding being useful as a supported catalyst for heterogeneous catalytic reactions. It also provides a direct one-step synthesis of pyrrole, furan and thiophene compounds from diallyl compounds.

  本发明提供了金属配合物，可用作交换反应中的催化剂组分，以及涉及将原子或基团转移至乙烯基或乙炔基不饱和化合物或其他反应底物的反应中，并且针对其亚类别，用于α-烯烃和可选的共轭二烯的聚合，具有在中等温度下高活性。它还提供了通过活性反应获得非常窄的分子量分布的聚合物的方法。它还提供了制备该金属配合物和涉及这种方法的新型中间体的方法。它还提供了该金属配合物的衍生物，适用于与载体进行共价键合，该共价键合的产物可用作异相催化反应的支持催化剂。它还提供了从双烯基化合物直接合成吡咯、呋喃和噻吩化合物的一步法。
• Metal complexes for use in metathesis, atom transfer radical reactions, addition polymerisation and vinylation reactions, methods and intermediates for making them
  申请人：UNIVERSITEIT GENT

  公开号：EP1743899A1

  公开（公告）日：2007-01-17

  This invention relates to metal complexes which are useful as catalyst components in olefin metathesis reactions, atom or group transfer radical polymerisation or addition reactions and vinylation reactions. It also relates to the direct one-step synthesis of pyrrole, furan and thiophene compounds, such as dialkyl 1H-pyrrol-1-yl methyl phosphonates, from diallyl compounds.

  本发明涉及在烯烃偏聚反应、原子或基团转移自由基聚合或加成反应以及乙烯基化反应中用作催化剂组分的金属络合物。本发明还涉及从二烯丙基化合物中一步直接合成吡咯、呋喃和噻吩化合物，如 1H-吡咯-1-基甲基膦酸二烷基酯。
• Gross, Hans; Ozegowski, Sigrid, Zeitschrift fur Chemie, 1982, vol. 22, # 5, p. 181
  作者：Gross, Hans、Ozegowski, Sigrid

  DOI：——

  日期：——
• GROSS, H.;BEISERT, S.;COSTISELLA, B., J. PRAKT. CHEM., 1981, 323, N 6, 877-886
  作者：GROSS, H.、BEISERT, S.、COSTISELLA, B.

  DOI：——

  日期：——
• GROSS, H.;OZEGOWSKI, S., Z. CHEM., 1982, 22, N 5, 181
  作者：GROSS, H.、OZEGOWSKI, S.

  DOI：——

  日期：——