1-(4-chlorophenyl)-N-naphthalen-1-ylmethanimine | 135569-53-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-(4-chlorophenyl)-N-naphthalen-1-ylmethanimine
• 英文别名: (E)-N-(4-chlorobenzylidene) naphthalen-1-amine；N-(α-naphthyl)-4-chlorobenzylimine；(4-chloro-benzylidene)-[1]naphthyl-amine；(4-Chlor-benzyliden)-[1]naphthyl-amin；4-Chlor-benzaldehyd-[1]naphthylimin
• CAS: 135569-53-8
• 化学式: C₁₇H₁₂ClN
• 分子量: 265.742
• InChiKey: UDMSFCIMUWEVRT-XDHOZWIPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.24
• 重原子数：
  19.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  1-(4-chlorophenyl)-N-naphthalen-1-ylmethanimine 、 N-苯基-N-甲基甘氨酸盐酸盐 在 三乙胺 、 对甲苯磺酰氯 作用下， 以 苯 为溶剂， 以73%的产率得到trans-1-α-naphthyl-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone
  参考文献：
  名称：

  Cycloaddition of (N-alkyl-N-phenylamino)ketene with imines

  摘要：

  (N-Alkyl-N-phenylamino)ketenes were prepared in the presence of various imines, and a [2 + 2] cycloaddition reaction occurred to yield 3-(N-alkyl-N-phenylamino)-2-azetidinones. The size and electronic nature of the imine substituents were varied in order to probe those factors that influence the stereochemistry of the cycloaddition. The stereochemistry of the 2-azetidinone was determined by the substitution pattern of the imines. In general, the stereochemistry of the 2-azetidinone products are significantly influenced by the bulk of the N substituent on the imine. These results are discussed in terms of a two-step zwitterionic intermediate.

  DOI：

  10.1021/jo00021a029
• 作为产物：
  描述：

  1-萘胺 、 4-氯苯甲醇 在 potassium tert-butylate 作用下， 以 正辛烷 为溶剂， 反应 24.0h， 以91%的产率得到1-(4-chlorophenyl)-N-naphthalen-1-ylmethanimine
  参考文献：
  名称：

  通过醇与胺的无受体脱氢偶联可持续地铁催化的亚胺直接形成

  摘要：

  据报道，使用非均相铁催化剂，醇与胺的无受体脱氢偶联（ADC）。

  DOI：

  10.1039/c6gc00565a

文献信息

• Schmeyers, Jens; Toda, Fumio; Boy, Juergen, Journal of the Chemical Society. Perkin Transactions 2 (2001), 1998, # 4, p. 989 - 993
  作者：Schmeyers, Jens、Toda, Fumio、Boy, Juergen、Kaupp, Gerd

  DOI：——

  日期：——
• Solankee, A. N.; Kapadia, K. M.; Desai, C. M., Journal of the Indian Chemical Society, 1992, vol. 69, # 11, p. 783 - 784
  作者：Solankee, A. N.、Kapadia, K. M.、Desai, C. M.

  DOI：——

  日期：——
• STRODS YA. A.; LIELBRIEDIS I. EH.; NEJLAND O. YA., XIMIYA GETEROTSIKL. SOEDIN., 1977, HO 7, 977-979
  作者：STRODS YA. A.、 LIELBRIEDIS I. EH.、 NEJLAND O. YA.

  DOI：——

  日期：——
• Cycloaddition of (N-alkyl-N-phenylamino)ketene with imines
  作者：William T. Brady、Mohammad M. Dad

  DOI：10.1021/jo00021a029

  日期：1991.10

  (N-Alkyl-N-phenylamino)ketenes were prepared in the presence of various imines, and a [2 + 2] cycloaddition reaction occurred to yield 3-(N-alkyl-N-phenylamino)-2-azetidinones. The size and electronic nature of the imine substituents were varied in order to probe those factors that influence the stereochemistry of the cycloaddition. The stereochemistry of the 2-azetidinone was determined by the substitution pattern of the imines. In general, the stereochemistry of the 2-azetidinone products are significantly influenced by the bulk of the N substituent on the imine. These results are discussed in terms of a two-step zwitterionic intermediate.
• Sustainable iron-catalyzed direct imine formation by acceptorless dehydrogenative coupling of alcohols with amines
  作者：Garima Jaiswal、Vinod G. Landge、Dinesh Jagadeesan、Ekambaram Balaraman

  DOI：10.1039/c6gc00565a

  日期：——

  The Acceptorless Dehydrogenative Coupling (ADC) of alcohols with amines is reported using a heterogeneous Fe-catalyst.

  据报道，使用非均相铁催化剂，醇与胺的无受体脱氢偶联（ADC）。