9-nitromethyl-xanthene | 61307-91-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 9-nitromethyl-xanthene
• 英文别名: 9-Nitromethyl-xanthen；9-(Nitromethyl)-9H-xanthene
• CAS: 61307-91-3
• 化学式: C₁₄H₁₁NO₃
• 分子量: 241.246
• InChiKey: QIVDISXVOKNYOA-UHFFFAOYSA-N

物化性质

• 沸点：
  381.6±21.0 °C(Predicted)
• 密度：
  1.263±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  9-nitromethyl-xanthene 在 溶剂黄146 、 锌 作用下， 生成 氧杂蒽-9-甲胺
  参考文献：
  名称：

  Wanag; Geita, Latvijas PSR Zinatnu Akademijas Vestis, 1952, # 10, p. 149,154

  摘要：

  DOI：
• 作为产物：
  描述：

  2-nitro-2-xanthen-9-yl-indane-1,3-dione 在 sodium hydroxide 作用下， 生成 9-nitromethyl-xanthene
  参考文献：
  名称：

  Wanag; Geita, Latvijas PSR Zinatnu Akademijas Vestis, 1952, # 10, p. 149,154

  摘要：

  DOI：

文献信息

• Metal-free TEMPO-catalyzed oxidative C–C bond formation from Csp3–H bonds using molecular oxygen as the oxidant
  作者：Bo Zhang、Yuxin Cui、Ning Jiao

  DOI：10.1039/c2cc30684k

  日期：——

  An efficient TEMPO-catalyzed oxidative C–C bond formation with two Csp3–H bonds using molecular oxygen as the oxidant has been developed. The novel transformation provides a new strategy for the TEMPO–O2 catalysis to construct C–C bonds. The advantages of this method include: (1) relatively mild and neutral conditions; (2) simplicity and safety of operation; (3) a stoichiometric amount of dangerous oxidants, any transition metals, additives, even solvent, is not required.

  一种高效的TEMPO催化氧化C–C键形成方法被开发出来，该方法利用分子氧作为氧化剂，实现了两个Csp3–H键的反应。这一新型转化过程为TEMPO–O2催化构建C–C键提供了新策略。该方法的优势包括：（1）条件相对温和且中性；（2）操作简便和安全性高；（3）无需使用危险氧化剂的化学计量量，不需要过渡金属、添加剂，甚至溶剂也不必使用。
• Manganese(III)-mediated carbon-carbon bond formation in the reaction of xanthenes with active methylene compounds
  作者：Hiroshi Nishino、Hironori Kamachi、Harumi Baba、Kazu Kurosawa

  DOI：10.1021/jo00039a010

  日期：1992.6

  Oxidation of xanthenes with manganese(III) acetate in the presence of active methylene compounds such as 1,3-dicarbonyl compounds, malononitrile derivatives, acetone, and nitromethane selectively gives 9-substituted xanthene derivatives in good yields. A similar oxidation of thioxanthene also yields 2-(9-thioxanthenyl)-1,3-dicarbonyl compounds in 57-91% yields. The obtained 2-(9-xanthenyl)-1,3-dicarbonyl compounds are readily converted to 2-(9-xanthenylidene)-1,3-dicarbonyl derivatives using manganese(III) complexes or 2,3-dichloro-5, 6-dicyano-1,4-benzoquinone. The mechanisms for the formation of 9-substituted xanthenes are discussed on the basis of the reaction of intermediates, the electron-donating substituent effect on the xanthene ring system, effect of additives, and comparison with a reaction of radical-trapping reagents.
• Reaction of Thiaxanthydrol With Compounds Containing Active Hydrogen¹
  作者：EUGENE SAWICKI、VINCENT T. OLIVERIO

  DOI：10.1021/jo01108a009

  日期：1956.2
• Wanag; Geita, Latvijas PSR Zinatnu Akademijas Vestis, 1952, # 10, p. 149,154
  作者：Wanag、Geita

  DOI：——

  日期：——