已经测量了一系列取代的9-苯基芴的p K a值。在与以前的研究相结合,结果使建立的ħ -为25-97%的含水二甲亚砜含有氢氧化四甲铵酸度函数。结果表明,在更多水溶液中,基于苯胺指示剂的电离,该比例与酸度功能不平行。芴环中的取代基对烃酸度的影响大于9-苯基核中的取代基。通过使用改良的Hammett方程,取代基与烃酸度的影响相关,表明9-苯环与芴核的平面度之间的距离约为。 39°,接近分子轨道计算先前预测的值。
Heterobimetallic Pd–Sn Catalysis: A Suzuki, Tandem Ring-Closing Sequence toward Indeno[2,1-<i>b</i>]thiophenes and Indeno[2,1-<i>b</i>]indoles
作者:Debjit Das、Sanjay Pratihar、Sujit Roy
DOI:10.1021/ol3021995
日期:2012.9.21
Indeno[2,1-b]thiophene and indeno[1,2-b]indole motifs have been obtained in moderate to good yields from easily available substituted boronic acids, 2-bromo aryl/vinyl aldehydes, and nucleophiles such as arenes/heteroarenes and others using a catalytic combination of bimetallic “Pd–Sn” and AgPF6. This formal three-component coupling involves a Suzuki reaction followed by nucleophile assisted tandem
茚并[2,1- b ]噻吩和茚并[1,2- b ]吲哚基序已经在中度至良好的产率从容易获得的取代的硼酸获得,2-溴芳基/乙烯基醛,和亲核试剂如芳烃/杂芳烃其他使用双金属“ Pd-Sn”和AgPF 6的催化组合。正式的三组分偶联涉及Suzuki反应,然后亲核试剂协助串联闭环。还完成了取代杂环稠合的茚,苯并芴和芴的顺序合成。
The irradiation of 2-chloro- or 2-bromo-1,3-diphenylindenyl anion causes dehalogenation to yield a hypovalent intermediate best described as 1,3-diphenylisoindenylidene or 1,3-diphenyl-1,2-dehydroindene. This intermediate undergoes facile CH insertion, addition to electron-rich olefins, and halide interchange. 23 references, 6 figures, 1 table.
Highly efficient synthesis of polysubstituted fluorene via iron-catalyzed intramolecular Friedel–Crafts alkylation of biaryl alcohols
作者:Soumen Sarkar、Sukhendu Maiti、Krishnendu Bera、Swapnadeep Jalal、Umasish Jana
DOI:10.1016/j.tetlet.2012.08.005
日期:2012.10
An efficient and mild Fe(III)-catalyzed intramolecular Friedel–Crafts alkylation of biaryl methanol derivatives has been developed to achieve the substituted fluorenederivatives. The present reaction provides an excellent alternative to published methods because of its high yields, operational simplicity, mild conditions, and use of inexpensive and sustainable catalyst.
Photochemical reactions of triarylmethyl peroxides (II) α- and β-naphthyldiphenylmethyl peroxide
作者:D.C. Neckers、Shwn-Mei Linden、Ross J. Taliano、B. Lee Williams、Andrei Zakrzewski
DOI:10.1016/0040-4039(88)85077-9
日期:1988.1
The photochemical decomposition of the title compounds and isotoplcally labeled analogs have been compared to the thermalreactions. Rapid radical 1,2-migration and reversible elimination of oxygen from the starting peroxides are indicated.
Generation and thermal bond relocation of a sterically congested cyclononatetraenyl anion
作者:A.G. Anastassiou、H.S. Kasmai、M. Hasan
DOI:10.1016/s0040-4039(00)98313-8
日期:1985.1
The sterically strained anion 4 was found to be thermally labile to subzero workup, readily undergoing temperature-dependent electrocyclization to a variety of tetracyclic frames.