2,3-Dimethyl-4,4-diphenyl-1-butene | 42842-40-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-Dimethyl-4,4-diphenyl-1-butene
• 英文别名: (2,3-Dimethyl-1-phenylbut-3-enyl)benzene
• CAS: 42842-40-0
• 化学式: C₁₈H₂₀
• 分子量: 236.357
• InChiKey: FVQMGJPEGVOYCO-UHFFFAOYSA-N

物化性质

• 沸点：
  322.4±22.0 °C(Predicted)
• 密度：
  0.955±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  二苯基溴甲烷 、 三丁基(2-甲基丁-2-烯基)锡烷 在 zinc chloride diethyl ether 作用下， 以 二氯甲烷 为溶剂， 反应 0.17h， 以90%的产率得到2,3-Dimethyl-4,4-diphenyl-1-butene
  参考文献：
  名称：

  Radical Reaction Initiated and Stereocontrolled by Zinc Chloride

  摘要：

  The reaction of allyltributyltin with methyl 2-[N-((4S)-4-(1-methylethyl)-2-oxazolidinone-3-carbamoyl)amino]-2-bromoacetate (5a) was accelerated at -50 degrees C in the presence of AIBN and stopped in the presence of galvinoxyl, indicating that the reaction proceeds through a radical mechanism. The reaction was accelerated dramatically at -78 degrees C in the presence of ZnCl2 . OEt2, and the ZnCl2-mediated reaction was stopped in the presence of galvinoxyl. In the presence of 2 equiv ZnCl2 . OEt2, the reaction afforded methyl (2R)-2-[N-((4S)-4-(1-methylethyl)-2-oxazolidinone-3- carbamoyl)amino]4-pentenoate {6a(R)} with high diastereoselectivity (93:7). Taken together, ZnCl2 . OEt2 works as a radical initiator as well as chelating agent.

  DOI：

  10.3987/com-97-s(n)71

文献信息

• Mayr, Herbert; Pock, Rudolf, Chemische Berichte, 1986, vol. 119, # 8, p. 2473 - 2496
  作者：Mayr, Herbert、Pock, Rudolf

  DOI：——

  日期：——
• Reactions of diphenylcarbene with alkenes, alkynes, and alkenynes
  作者：William J. Baron、Michael E. Henrick、Maitland. Jones

  DOI：10.1021/ja00800a022

  日期：1973.9
• Regioselectivity and rearrangement upon addition of nucleophiles to dieneiron complexes
  作者：M. F. Semmelhack、Hanh T. M. Le

  DOI：10.1021/ja00321a049

  日期：1984.5
• Nucleophilic addition to coordinated polyenes: a novel method for the liberation of the trimethylenemethane ligand involving CC bond formation
  作者：William A. Donaldson、M.Azad Hossain

  DOI：10.1016/s0040-4039(00)74664-8

  日期：1992.7

  Reaction of (trimethylenemethane)Fe(CO)3 with carbon nucleophiles, followed by protonation yields the corresponding methallylated nucleophile in good yield. Products which incorporate carbonyl ligands are also observed.
• MAYR H.; POCK R., CHEM. BER., 119,(1986) N 8, 2473-2496
  作者：MAYR H.、 POCK R.

  DOI：——

  日期：——