acetic acid 2,4,6-triiodophenyl ester | 957137-55-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: acetic acid 2,4,6-triiodophenyl ester
• 英文别名: Trijodphenylacetat；2,4,6-tri-I3C6H2OAc；Essigsaeure-(2,4,6-trijod-phenylester)；(2.4.6-Trijod-phenyl)-acetat；(2,4,6-triiodophenyl) acetate
• CAS: 957137-55-2
• 化学式: C₈H₅I₃O₂
• 分子量: 513.84
• InChiKey: HUTDLXJVEMRNPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.43
• 重原子数：
  13.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  acetic acid 2,4,6-triiodophenyl ester 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 肼 作用下， 生成 2,4,6-tri-hex-1-ynyl-phenol
  参考文献：
  名称：

  Novel Pd^II-Mediated Cascade Carboxylative Annulation to Construct Benzo[b]furan-3-carboxylic Acids

  摘要：

  Benzo[b]furan-3-carboxylic acid (2) was generated from 1 by forming three new bonds in one step via a Pd-II-mediated cascade carboxylative annulation. The proposed mechanism was supported by the observation of an unusual acetylation of 1 as a side reaction together with an O-18-labeling study.

  DOI：

  10.1021/ol050876g
• 作为产物：
  描述：

  苯酚 在 硫酸 作用下， 生成 acetic acid 2,4,6-triiodophenyl ester
  参考文献：
  名称：

  King; Mc Combie, Journal of the Chemical Society, 1913, vol. 103, p. 230

  摘要：

  DOI：

文献信息

• Silver Triflate Catalyzed Acetylation of Alcohols, Thiols, Phenols, and Amines
  作者：Debashis Chakraborty、Rima Das

  DOI：10.1055/s-0030-1259999

  日期：2011.5

  variety of alcohols, thiols, phenols, and amines were subjected to acetylation reaction using acetic anhydride in the presence of catalytic quantity of silver triflate. The method described has a wide range of applications, proceeds under mild conditions, does not involve cumbersome workup, and the resulting products are obtained in high yields within a reasonable time. acetylation - silver triflate -

  在催化量的三氟甲磺酸银存在下，使用乙酸酐对各种醇，硫醇，酚和胺进行乙酰化反应。所描述的方法具有广泛的应用，在温和的条件下进行，不涉及繁琐的后处理，并且在合理的时间内以高收率获得了所得产物。 乙酰化-三氟甲磺酸银-醇-苯酚-硫醇-胺
• Directed Ortho Insertion (DoI):  A New Approach to Functionalized Aryl and Heteroaryl Zinc Reagents
  作者：Nadège Boudet、Shohei Sase、Pradipta Sinha、Ching-Yuan Liu、Arkady Krasovskiy、Paul Knochel

  DOI：10.1021/ja074060h

  日期：2007.10.1

  A wide range of directing groups (ester, ketone, acetate, aryl sulfonate, triazene, carbamate) allow the regioselective directed ortho insertion (DoI) of zinc in the presence of LiCl leading to polyfunctional aryl and heteroaryl zinc reagents.

  范围广泛的导向基团（酯、酮、乙酸酯、芳基磺酸盐、三氮烯、氨基甲酸酯）允许在 LiCl 存在下区域选择性定向邻位插入（DoI）锌，从而产生多官能的芳基和杂芳基锌试剂。
• Brenans, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901, vol. 133, p. 161
  作者：Brenans

  DOI：——

  日期：——