O-(9H-fluoren-9-yl)methyl S-phenyl carbonothioate | 1256374-76-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: O-(9H-fluoren-9-yl)methyl S-phenyl carbonothioate
• 英文别名: 9H-fluoren-9-ylmethyl phenylsulfanylformate
• CAS: 1256374-76-1
• 化学式: C₂₁H₁₆O₂S
• 分子量: 332.423
• InChiKey: ABUYWXCACQLMQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  氯甲酸-9-芴基甲酯 、 二苯二硫醚 在 copper(II) oxide 作用下， 反应 0.05h， 以50%的产率得到O-(9H-fluoren-9-yl)methyl S-phenyl carbonothioate
  参考文献：
  名称：

  微波辐射下使用纳米CuO/离子液体作为环保还原体系合成硫醇酯

  摘要：

  我们报告了一种使用稳定的二有机酰二硫化物和酰氯，使用 CuO 纳米颗粒和 [pmim]Br 作为还原系统合成各种硫羟酸酯的高效、快速和环保的方法。该方法仅在微波辐射三分钟后就获得了良好至极好的分离产率。此外，通过使用相同的绿色方法，我们还能够合成具有有趣功能的硫代碳酸盐。

  DOI：

  10.1002/ejoc.201300295

文献信息

• Zn in ionic liquid: an efficient reaction media for the synthesis of diorganyl chalcogenides and chalcogenoesters
  作者：Senthil Narayanaperumal、Eduardo E. Alberto、Kashif Gul、Cristiane Yuriko Kawasoko、Luciano Dornelles、Oscar E.D. Rodrigues、Antonio Luiz Braga

  DOI：10.1016/j.tet.2011.04.018

  日期：2011.6

  A straightforward and efficient methodology is described to synthesize structurally diverse diorganyl selenides, sulfides, seleno- and thioesters by using commercially available Zn dust in ionic liquid. Excellent yields were achieved under neutral conditions at room temperature in a short time. The solvent/ionic liquid is reusable and exhibited higher performance as compared with organic solvents. (C) 2011 Elsevier Ltd. All rights reserved.
• Ionic liquid: an efficient and reusable media for seleno- and thioester synthesis promoted by indium
  作者：Greice Tabarelli、Eduardo E. Alberto、Anna M. Deobald、Graciane Marin、Oscar E.D. Rodrigues、Luciano Dornelles、Antonio L. Braga

  DOI：10.1016/j.tetlet.2010.08.076

  日期：2010.10

  A series of thio and selenoesters were efficiently obtained employing stable diorganyl chalcogenides, acyl chlorides, and In as reducing agent in BMIM center dot PF6. Recycling of the ionic liquid was also performed, which was reused three times. (C) 2010 Elsevier Ltd. All rights reserved.
• Synthesis of Thiol Esters Using Nano CuO/Ionic Liquid as an Eco-Friendly Reductive System Under Microwave Irradiation
  作者：Juliano B. Azeredo、Marcelo Godoi、Ricardo S. Schwab、Giancarlo V. Botteselle、Antonio L. Braga

  DOI：10.1002/ejoc.201300295

  日期：2013.8

  We report an efficient, fast, and environmentally friendly method for the synthesis of a wide range of thiol esters using stable diorganoyl disulfides and acyl chlorides, using CuO nanoparticles and [pmim]Br as the reductive system. This method gave good to excellent isolated yields of the desired products after only three minutes of microwave irradiation. Furthermore, by using the same green approach

  我们报告了一种使用稳定的二有机酰二硫化物和酰氯，使用 CuO 纳米颗粒和 [pmim]Br 作为还原系统合成各种硫羟酸酯的高效、快速和环保的方法。该方法仅在微波辐射三分钟后就获得了良好至极好的分离产率。此外，通过使用相同的绿色方法，我们还能够合成具有有趣功能的硫代碳酸盐。