2,6-naphthalenedicarboxamide | 46711-49-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,6-naphthalenedicarboxamide
• 英文别名: 2,6-naphthalenediamide；naphthalene-2,6-dicarboxamide；Naphthalin-2,6-dicarbamid；Napthalene-2,6-dicarboxylic acid monoamide
• CAS: 46711-49-3
• 化学式: C₁₂H₁₀N₂O₂
• 分子量: 214.224
• InChiKey: COWHOTSOONQDCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  86.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,6-naphthalenedicarboxamide 在 potassium fluoride 、 硼烷四氢呋喃络合物 、 Celite 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 反应 21.0h， 生成
  参考文献：
  名称：

  Design, synthesis, and characterization of a novel hexa-azacyclophane and interactions with d(CGCA3T3GCG)2, ctDNA and T4DNA

  摘要：

  A novel polyazacyclophane hexa-amine (1) has been designed, synthesized and characterized by X-ray crystallography, H-1 NMR and fluorescence spectroscopy. 1 has the structural shape and disposition of charges complementary to the major groove of B-DNA. Acid dissociation constants for the protonated 1 were pK(a1)(D)= 4.8 and pK(a2)(D)= 8.5. Equilibrium constants for the binding of 1 to ctDNA and T4 DNA were 1.2 x 10(5) and 1.8 x 10(6), respectively. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00501-2
• 作为产物：
  描述：

  2,6-萘二羧酸 在 ammonium 作用下， 反应 0.5h， 生成 2,6-naphthalenedicarboxamide
  参考文献：
  名称：

  腈及其相应胺的制造方法

  摘要：

  本发明涉及一种腈的制造方法，与现有技术相比，具有氨源用量显著降低、环境压力小、能耗低、生产成本低、腈产品的纯度和收率高等特点，并且能够获得结构更为复杂的腈。本发明还涉及由该腈制造相应胺的方法。

  公开号：

  CN105001032B

文献信息

• Cyclic imino derivatives and pharmaceutical compositions containing them
  申请人：Karl Thomae GmbH

  公开号：US05541343A1

  公开（公告）日：1996-07-30

  The invention relates to cyclic imino compounds which have, inter alia, valuable pharmacological properties, especially inhibitory effects on cell aggregation, pharmaceutical compositions which contain these compounds and processes for preparing them.

  这项发明涉及具有有价值的药理特性，特别是对细胞聚集具有抑制作用的环亚胺化合物，包含这些化合物的药物组合物以及制备它们的方法。
• 腈及其相应胺的制造方法
  申请人：中国石化扬子石油化工有限公司

  公开号：CN105001032B

  公开（公告）日：2018-03-16

  本发明涉及一种腈的制造方法，与现有技术相比，具有氨源用量显著降低、环境压力小、能耗低、生产成本低、腈产品的纯度和收率高等特点，并且能够获得结构更为复杂的腈。本发明还涉及由该腈制造相应胺的方法。
• POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES
  申请人：Peters Richard Dalton

  公开号：US20120199515A1

  公开（公告）日：2012-08-09

  Disclosed is a polyester polymer composition comprising at least one polyethylene terephthalate polyester in an amount ranging from 94.0 weight percent to 99.5 weight percent and at least one additive in an amount ranging from 0.5 weight percent to 6 weight percent, each based on the total weight of the polyester composition. The at least one additive comprises a diamide molecule. The composition of the present invention is useful in producing shaped articles such as, for example, sheeting, films, tubes, bottles, preforms, and profiles. These articles can exhibit improved gas barrier properties. The process for making the polymer composition and the shaped articles is also disclosed.

  本发明公开了一种聚酯聚合物组合物，其包括至少一种聚对苯二甲酸乙二醇酯聚酯，其含量在94.0重量百分比至99.5重量百分比之间，并且至少一种添加剂，其含量在0.5重量百分比至6重量百分比之间，每种都基于聚酯组合物的总重量。所述至少一种添加剂包括一种二酰胺分子。本发明的组合物可用于生产成型物品，例如，薄膜、管道、瓶子、预制体和型材。这些物品可以表现出改善的气体屏障性能。本发明还公开了制备聚合物组合物和成型物品的方法。
• Polyesters with low molecular weight additives for improved gas barrier properties
  申请人：Peters Richard Dalton

  公开号：US08377530B2

  公开（公告）日：2013-02-19

  Disclosed is a polyester polymer composition comprising at least one polyethylene terephthalate polyester in an amount ranging from 94.0 weight percent to 99.5 weight percent and at least one additive in an amount ranging from 0.5 weight percent to 6 weight percent, each based on the total weight of the polyester composition. The at least one additive comprises a diamide molecule. The composition of the present invention is useful in producing shaped articles such as, for example, sheeting, films, tubes, bottles, preforms, and profiles. These articles can exhibit improved gas barrier properties. The process for making the polymer composition and the shaped articles is also disclosed.

  本发明揭示了一种聚酯聚合物组合物，其包括至少一种聚对苯二甲酸乙二醇酯聚酯，其含量范围为94.0重量百分比至99.5重量百分比，并且至少包括一种添加剂，其含量范围为0.5重量百分比至6重量百分比，每个基于聚酯组合物的总重量。至少一种添加剂包括一种二酰胺分子。本发明的组合物可用于生产成型品，例如片材、薄膜、管、瓶、预制件和型材。这些制品可以表现出改进的气体阻隔性能。本发明还揭示了制备聚合物组合物和成型品的工艺。
• Process for preparing 2,6-naphthalenedicarboxylic acid
  申请人：Mitsubishi Chemical Corporation

  公开号：EP0496264A2

  公开（公告）日：1992-07-29

  A process for preparing 2,6-naphthalenedicarboxylic acid comprising oxidation reaction of 2,6-diisopropylnaphthalene or an oxidation product thereof with molecular oxygen in a solvent containing an aliphatic carboxylic acid in the presence of a catalyst comprising cobalt and manganese as heavy metals and a bromine compound is disclosed, in which said oxidation reaction is carried out in the presence of at least one nitrogen-containing compound selected from the group consisting of a pyridine compound, ammonia, a carboxylic acid ammonium salt, urea, a urea derivative, an amine, and a carboxylic acid amide. 2,6-Naphthalenedicarboxylic acid can be obtained at higher purity and in increased yield.

  本发明公开了一种制备 2,6-萘二甲酸的工艺，该工艺包括 2,6-二异丙基萘或其氧化产物在含有脂肪族羧酸的溶剂中与分子氧在由重金属钴和锰以及溴化合物组成的催化剂存在下进行的氧化反应、其中所述氧化反应是在至少一种选自吡啶化合物、氨、羧酸铵盐、脲、脲衍生物、胺和羧酸酰胺的含氮化合物存在下进行的。2,6-萘二甲酸的纯度更高，产率更高。