6-methyl-2-(3-methylpyrazol-1-yl)pyridine | 526224-67-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-methyl-2-(3-methylpyrazol-1-yl)pyridine
• 英文别名: 2-Methyl-6-(3-methyl-1H-pyrazol-1-yl)pyridine；2-methyl-6-(3-methylpyrazol-1-yl)pyridine
• CAS: 526224-67-9
• 化学式: C₁₀H₁₁N₃
• 分子量: 173.217
• InChiKey: ACAVYYDDSCSHSN-UHFFFAOYSA-N

物化性质

• 沸点：
  293.8±28.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-methyl-2-(3-methylpyrazol-1-yl)pyridine 在 potassium permanganate 作用下， 以 吡啶 、 水 为溶剂， 反应 14.0h， 以55%的产率得到1-(6-Methylpyridin-2-yl)pyrazole-3-carboxylic acid
  参考文献：
  名称：

  Tripod molecules based on the N,C-pyrazolyl-pyridine motif

  摘要：

  The synthesis of four new podands with three arms containing the N,C-pyrazolyl-pyridine chromophore is described with the aim of using the resulting tripods as ligands to sensitize lanthanide luminescence. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.107
• 作为产物：
  描述：

  2-甲基-6-氯吡啶 、 3-甲基吡唑 在 氢化钾 作用下， 以 二乙二醇二甲醚 为溶剂， 反应 96.0h， 以76%的产率得到6-methyl-2-(3-methylpyrazol-1-yl)pyridine
  参考文献：
  名称：

  Tripod molecules based on the N,C-pyrazolyl-pyridine motif

  摘要：

  The synthesis of four new podands with three arms containing the N,C-pyrazolyl-pyridine chromophore is described with the aim of using the resulting tripods as ligands to sensitize lanthanide luminescence. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.107

文献信息

• Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors
  申请人：BASF SE

  公开号：US20140323305A1

  公开（公告）日：2014-10-30

  The present invention relates to the use of strobilurine type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing a mutation in the mitochondrial cytochrome b gene conferring resistance to Qo inhibitors, and to methods for combating such fungi. The invention also relates to novel compounds, processes for preparing these compounds, to compositions comprising at least one such compound, to plant health applications, and to seeds coated with at least one such compound.

  本发明涉及使用式I的蘑菇酸类化合物以及其N-氧化物和盐来对抗含有对Qo抑制剂产生耐药性的线粒体细胞色素b基因突变的植物病原真菌，以及对抗这类真菌的方法。该发明还涉及新颖的化合物、制备这些化合物的方法、包含至少一种这样的化合物的组合物、植物健康应用以及至少一种这样的化合物包被的种子。
• A Water‐Stable and Strongly Luminescent Terbium(III) Macrocyclic Complex Incorporating an Intracyclic Pyrazolylpyridine Chromophore
  作者：Isabelle Nasso、Sébastien Bedel、Chantal Galaup、Claude Picard

  DOI：10.1002/ejic.200701209

  日期：2008.4

  photophysical studies were performed in aerated water on the free ligand and its GdIII complex and complexes formed with LnIII ions commonly used in fluoroimmunoassays (Ln = Sm, Eu, Tb, and Dy). The results show a wide range in the emission properties of the complexes, which can be rationalized in terms of the chromophore triplet-state energy. In particular, the TbIII complex has a remarkable overall quantum yield

  设计了一个 15 元大环配体 L1H3，目的是使水中 TbIII 离子的可见发光敏感：这种八齿螯合配体基于环内 N,C-吡唑基吡啶发色团和二亚乙基三胺三乙酸核。该配体与等摩尔量的 LnCl3 盐反应，生成具有通式 [L1·Ln(H2O)]0 的水溶性且稳定的复合物。在充气水中对游离配体及其 GdIII 复合物以及与荧光免疫分析中常用的 LnIII 离子形成的复合物（Ln = Sm、Eu、Tb 和 Dy）进行了详细的光物理研究。结果表明配合物的发射特性范围很广，这可以根据发色团三重态能量进行合理化。特别是，TbIII 复合物具有显着的总量子产率约。50 % 的 （80 % 的 D2O）和从敏化剂到约 2 的铽离子的能量转移效率。85%。根据这些结果并考虑到其在水溶液中的动力学惰性，L1·Tb 复合物可被认为是一种非常有前途的候选生物亲和性分析的长寿命发光标记。(© Wiley-VCH Verlag
• STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI
  申请人：BASF SE

  公开号：US20160122327A1

  公开（公告）日：2016-05-05

  The present invention relates to novel strobilurine type compounds I, processes for preparing these compounds, a use of compounds of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi, to compositions comprising at least one such compound, to plant health applications, and to seeds coated with at least one such compound.

  本发明涉及新型的链霉菌素类化合物I，制备这些化合物的方法，化合物I及/或其农业有用的盐用于控制植物病原真菌，至少包含一种这样的化合物的组合物，植物健康应用，以及至少涂覆一种这样的化合物的种子。
• Strobilurin Type Compounds for Combating Phytopathogenic Fungi
  申请人：BASF SE

  公开号：US20160145202A1

  公开（公告）日：2016-05-26

  The present invention relates to novel strobilurine type compounds, to compositions comprising at least one such compound, to methods for combating phytopathogenic fungi, to the use of such compounds and to seeds coated with at least one such compound.

  本发明涉及新型的环丙基丙烯酸酯类化合物，涉及至少含有该化合物的组合物，涉及用于对抗植物病原真菌的方法，涉及使用该类化合物以及至少含有该类化合物的种子涂层。
• Direct synthesis of new cryptates based on the N,C-pyrazolylpyridine motif
  作者：Ernesto Brunet、Olga Juanes、Miguel Angel Rodríguez-Blasco、Suzana Pereira Vila-Nueva、David Garayalde、Juan Carlos Rodríguez-Ubis

  DOI：10.1016/j.tetlet.2005.09.020

  日期：2005.11

  An expeditious synthesis of new cryptands derived from N,C-pyrazolylpyridine and their full characterization is reported. Emission lifetimes of the europium and terbium cryptates were in the range of milliseconds and terbium quantum yield was high. (c) 2005 Elsevier Ltd. All rights reserved.