Phenyl-bis(2-pyridin-2-ylethyl)phosphane | 113848-96-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Phenyl-bis(2-pyridin-2-ylethyl)phosphane
• CAS: 113848-96-7
• 化学式: C₂₀H₂₁N₂P
• 分子量: 320.374
• InChiKey: NBUYMYZCHIUHLE-UHFFFAOYSA-N

物化性质

• 沸点：
  484.7±40.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Phenyl-bis(2-pyridin-2-ylethyl)phosphane 、 anti-(μ-Cl)₂-[Pd₂(C₆Cl₂F₃)₂(tht)₂] 以 二氯甲烷 为溶剂， 以81%的产率得到
  参考文献：
  名称：

  P(CH₂CH₂Py)_nPh_3-n (Py = 2-Pyridyl; n = 1, 2, 3) as Chelating and as Binucleating Ligands for Palladium

  摘要：

  Several neutral palladium(II) complexes of the type [PdRCl(PNn)] with the ligands P(CH2CH2Py)Ph-2 (PN), P(CH2CH2Py)(2)Ph (PN2), and P(CH2CH2Py)(3) (PN3) have been prepared by reacting the corresponding phosphines with [Pd-2(mu-Cl)(2)R-2(tht)(2)] (R = C6Cl2F3, C6F5; tht = tetrahydrothiophene). In all these complexes, the ligands act as bidentate P,N-chelating ligands. Abstraction of the chloride with AgBF4 leads to the formation of the dimeric compounds [Pd2R2(PN2)(2)](BF4)(2) and [Pd2R2(PN3)(2)](BF4)(2), in which the PNn ligands act as P,N-chelating and P,N-bridging ligands. The bridges are labile, and exchange experiments on mixtures of the complexes with different R groups show the equilibrium in solution between the dimeric ''pure'' complexes and the mixed complexes [Pd-2(C6F5)(C6Cl2F3)(PNn)(2)](2+). The structure of the complex [Pd-2(C6Cl2F3)(2)(P(CH2CH2Py)(2)Ph)(2)](BF4)(2) has been studied by X-ray diffraction.

  DOI：

  10.1021/ic970745e
• 作为产物：
  描述：

  苯基膦 在 乙醚 、 甲基锂 作用下， 反应 4.0h， 生成 Phenyl-bis(2-pyridin-2-ylethyl)phosphane
  参考文献：
  名称：

  Spiegel, Gerd U.; Stelzer, Othmar, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1987, vol. 42, # 5, p. 579 - 588

  摘要：

  DOI：

文献信息

• Rhodium Complexes with the Chelating and Binucleating Ligands P(CH₂CH₂Py)<i>_n</i>Ph₃_-<i>_n</i> (Py = 2-Pyridyl; <i>n</i> = 1, 2):  Structures and Fluxional Behavior
  作者：M. Aránzazu Alonso、Juan A. Casares、Pablo Espinet、Katerina Soulantica、Jonathan P. H. Charmant、A. Guy Orpen

  DOI：10.1021/ic990634a

  日期：2000.2.1

  diene = 1,5-cyclooctadiene. The fluxional behavior of all these complexes is studied by NMR spectroscopy. The complex [Rh(NBD)(PePy2)]PF6.Cl2CH2 crystallizes in the monoclinic space group P21/n with a = 8.455(1) A, b = 18.068(3) A, c = 19.729(3) A, beta = 99.658(3)degrees, and Z = 4. The complexes [Rh(diene)(PePy2)]+ react with CO to give the dimeric complex [Rh2(CO)2[P(CH2CH2Py)2Ph]2](BF4)2 with the

  [RhX（CO）（PePy2）]，[Rh（diene）（PePy2）] +和[Rh（diene）（PePy2）] +（PePyn = P（CH2CH2Py）nPh3- n； Py ＝ 2-吡啶基； n ＝ 1、2）已经制备。前两个是方形平面；另一个是方形平面。对于二烯＝四氟苯并戊烯或降冰片二烯（通过X射线衍射证实），后者是五配位的，但是对于二烯＝ 1，5-环辛二烯，在溶液中存在4-和5-配位异构体的平衡。通过NMR光谱研究所有这些配合物的通量行为。复合物[Rh（NBD）（PePy2）] PF6.Cl2CH2在单斜空间群P21 / n中结晶，其中a = 8.455（1）A，b = 18.068（3）A，c = 19.729（3）A，β= 99.658（3）度，Z =4。配合物[Rh（diene）（PePy2）] +与CO反应生成二聚体配合物[Rh2（CO）2 [P（CH2CH2Py）2Ph]
• A Study of Two Highly Active, Air-Stable Iron(III)-μ-Oxo Precatalysts: Synthetic Scope of Hydrophosphination using Phenyl- and Diphenylphosphine
  作者：Kimberley J. Gallagher、Maialen Espinal-Viguri、Mary F. Mahon、Ruth L. Webster

  DOI：10.1002/adsc.201501179

  日期：2016.7.28

  The importance of phosphines in synthetic chemistry cannot be underestimated. Catalytic hydrophosphination offers an ideal method to prepare P−C bonds without the need for harsh reaction conditions or stoichiometric amounts of waste by‐product. We herein report our studies into two biocompatible iron(III) complexes in hydrophosphination chemistry using diphenylphosphine under mild and benign reaction

  膦在合成化学中的重要性不可低估。催化加氢磷酸化提供了制备P-C键的理想方法，而无需苛刻的反应条件或化学计量的废物副产物。我们在此报告了我们在温和和良性反应条件（室温，无溶剂）下使用二苯膦在氢磷化化学中对两种生物相容的铁（III）配合物的研究，以及我们对苯膦进行氢磷化的扩展探索，可以将其调整为在不存在的情况下运行在热条件下进行单加氢磷化或在无溶剂的情况下使用铁（III）预催化剂生成双加氢磷化产物的催化剂。
• Hydrophosphination of alkenes and alkynes with primary phosphines catalyzed by zirconium complexes bearing aminophenolato ligands
  作者：Yu Zhang、Xinxin Wang、Yaorong Wang、Dan Yuan、Yingming Yao

  DOI：10.1039/c8dt02122h

  日期：——

  activity and chemo-selectivity in catalyzing intermolecular hydrophosphination of C–C multiple bonds with primary phosphines under mild conditions. A broad range of alkenes and alkynes underwent a mono-addition reaction with phenylphosphine, which generated secondary phosphines in 39–99% yields and >7 : 1 selectivity (over double hydrophosphination).

  由胺桥联的双（酚基）配体稳定的锆配合物在温和条件下，在催化带有主膦的CC多重键的分子间加氢磷酸化方面表现出良好的活性和化学选择性。广泛的烯烃和炔烃与苯基膦进行单加成反应，生成次膦的产率为39-99％，选择性大于7：1（双氢磷化处理）。
• A Simple Manganese(I) Catalyst for the Efficient and Selective Hydrophosphination of Olefins with PH₃, Primary, and Secondary Phosphanes
  作者：Aabid A. Wani、Juan José Gamboa Carballo、Harikrishnan Jayaprakash、Michael Wörle、Anna Widera、Antonio Togni、Hansjörg Grützmacher

  DOI：10.1002/chem.202303848

  日期：2024.4.5

  amido complex with a tridentate P,N,N ligand, which is easily synthesized from commercially available chemicals, is a remarkable efficient (pre)catalyst for the hydrophosphination of alkenes using secondary and primary aryl and alkyl phosphines and even PH3 as reagents.

  具有三齿 P,N,N 配体的 Mn(I) 酰胺络合物很容易由市售化学品合成，是一种使用仲和伯芳基膦、烷基膦甚至 PH 进行烯烃氢膦酸化的高效（预）催化剂3作为试剂。
• SPIEGEL G. U.; STELZER O., Z. NATURFORSCH., 42,(1987) N 5, 579-588
  作者：SPIEGEL G. U.、 STELZER O.

  DOI：——

  日期：——