N-(cyclopentyl(morpholino)methylene)-4-methylbenzenesulfonamide | 96977-72-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(cyclopentyl(morpholino)methylene)-4-methylbenzenesulfonamide
• 英文别名: N,N-<3-Oxa-pentamethylen>-N'-p-toluolsulfonyl-C-cyclopentyl-formamidin；4-[N-(toluene-4-sulfonyl)-cyclopentanecarboximidoyl]-morpholine；N-[cyclopentyl(morpholin-4-yl)methylidene]-4-methylbenzenesulfonamide
• CAS: 96977-72-9
• 化学式: C₁₇H₂₄N₂O₃S
• 分子量: 336.455
• InChiKey: GEEAJZULPHYPOZ-UHFFFAOYSA-N

物化性质

• 沸点：
  491.5±55.0 °C(Predicted)
• 密度：
  1.28±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  67.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-吗啉基-1-环己烯 、 对甲苯磺酰叠氮 生成 N-(cyclopentyl(morpholino)methylene)-4-methylbenzenesulfonamide
  参考文献：
  名称：

  Fusco,R. et al., Gazzetta Chimica Italiana, 1961, vol. 91, p. 933 - 957

  摘要：

  DOI：

文献信息

• Fusco,R. et al., Gazzetta Chimica Italiana, 1961, vol. 91, p. 933 - 957
  作者：Fusco,R. et al.

  DOI：——

  日期：——
• Facile Synthesis of Sulfonyl Amidines by 1,3-Dipolar Cycloaddition between 1-Morpholinocycloalkenes and Sulfonyl Azides without Catalyst
  作者：Douniazad El Abed、Chiaa Adiche、Mohammed Hamadouche

  DOI：10.3987/com-16-13503

  日期：——

  Three new series of sulfonyl amidines were prepared by 1,3-dipolar cycloaddition reaction between 1-morpholinocycloalkenes and various substituted sulfonyl azides without catalyst at room temperature. This reaction yielded unstable bicyclic Delta(2)-1,2,3-triazoline intermediates which rearranged themselves in situ into amidines by elimination of a nitrogen molecule. The reactions were performed under mild conditions and with moderate to good yields.