3-甲基-2-(3-甲基丁-2-烯基)苯酚 | 88097-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 3-甲基-2-(3-甲基丁-2-烯基)苯酚
• 英文名称: 3-methyl-2-(3-methylbut-2-enyl)phenol
• 英文别名: 2-isopentenyl-3-methylphenol；3-Methyl-2-(3-methylbut-2-en-1-yl)phenol
• CAS: 88097-05-6
• 化学式: C₁₂H₁₆O
• 分子量: 176.258
• InChiKey: FNTSBOZQCUPFTD-UHFFFAOYSA-N

物化性质

• 沸点：
  277.2±9.0 °C(Predicted)
• 密度：
  0.979±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-甲基-3-丁烯-2-醇 、 间甲酚 在 aluminum oxide 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 5-甲基-2-(3-甲基丁-2-烯基)苯酚 、 3-甲基-2-(3-甲基丁-2-烯基)苯酚
  参考文献：
  名称：

  [EN] PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS
  [FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS HYDROXYPHÉNYLE ORTHO-ALLYLÉS

  摘要：

  The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted.

  公开号：

  WO2022266765A1

文献信息

• Regiospecific alkenylation of phenols by 1,1-dimethylallene promoted by platinum catalysts
  作者：Augusto De Renzi、Achille Panunzi、Antonio Saporito、Aldo Vitagliano

  DOI：10.1039/p29830000993

  日期：——

  1,1-Dimethylallene reacts with phenolic substrates in the presence of catalytic amounts of platinum(II) complexes. A regiospecific C-alkenylation takes place, affording o-isopentenylphenols and 2,2-dimethylchromans. Possible reaction mechanisms are also discussed.

  在催化量的铂（II）配合物的存在下，1,1-二甲基丙烯与酚类底物反应。发生区域特异性的C-烯基化，得到邻-异戊烯基苯酚和2，2-二甲基苯并二氢吡喃。还讨论了可能的反应机理。
• Felice, Vincenzo De; Renzi, Augusto De; Funicello, Maria, Gazzetta Chimica Italiana, 1985, vol. 115, # 1, p. 13 - 16
  作者：Felice, Vincenzo De、Renzi, Augusto De、Funicello, Maria、Panunzi, Achille、Saporito, Antonio

  DOI：——

  日期：——
• [EN] PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS<br/>[FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS HYDROXYPHÉNYLE ORTHO-ALLYLÉS
  申请人：[en]MCMASTER UNIVERSITY

  公开号：WO2022266765A1

  公开（公告）日：2022-12-29

  The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted.