2,5-Dimethyl-3,4-furandicarboxylic acid | 14597-13-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃
• 英文名称: 2,5-Dimethyl-3,4-furandicarboxylic acid
• 英文别名: 2,5-Dimethyl-furan-3,4-dicarbonsaeure；2,5-dimethylfuran-3,4-dicarboxylic acid
• CAS: 14597-13-8
• 化学式: C₈H₈O₅
• mdl: MFCD00092519
• 分子量: 184.149
• InChiKey: IDYRARBMMCSVMD-UHFFFAOYSA-N

物化性质

• 熔点：
  225 °C
• 沸点：
  350.7±42.0 °C(Predicted)
• 密度：
  1.418±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  87.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,5-Dimethyl-3,4-furandicarboxylic acid 在 二硫化碳 、 三氯化铝 、 氯化亚砜 作用下， 生成 1,3,5,7-tetramethyl-naphtho[2,3-c]furan-4,9-quinone
  参考文献：
  名称：

  Acylations with the Acid Chlorides of 2,5-Diphenylfuran-3,4-dicarboxylic Acid and 2,5-Dimethylfuran-3,4-dicarboxylic Acid and Related Compounds

  摘要：

  DOI：

  10.1021/jo01086a013
• 作为产物：
  描述：

  2,3-二乙酰基丁二酸二乙酯 在 盐酸 作用下， 以 水 为溶剂， 反应 1.0h， 以100%的产率得到2,5-Dimethyl-3,4-furandicarboxylic acid
  参考文献：
  名称：

  由2,3-二乙酰基琥珀酸二乙酯简单制备2,5-二甲基呋喃-3-羧酸乙酯和2,5-二甲基呋喃-3,4-二羧酸

  摘要：

  2,5-二甲基呋喃-3-羧酸乙酯的简单制备方法（），2,5-二甲基呋喃-3,4-二羧酸（）， 和 2,5-二甲基呋喃-3,4-二羧酸二乙酯（）通过处理2,3-二乙酰基琥珀酸二乙酯（报道有HCl水溶液。该反应在无有机溶剂的条件下由容易获得的廉价原料进行。J.杂环化​​学，（2009）。

  DOI：

  10.1002/jhet.92

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• Dimethylfurano heterocyclic analogs of daunomycin
  申请人：American Cyanamid Company

  公开号：US04585760A1

  公开（公告）日：1986-04-29

  Dimethyfurano analogs of daunomycin are described, including (.+-.)-8.alpha.-acetyl-6,7,8,9-tetrahydro-5,6.beta.,8.beta.,10-tetrahydrox y-1,3-dimethyl-anthra[2,3-c]-furan-4,11-dione-6-(3-amino-2,3-6-trideoxy-.al pha.-L-lyxo-hexopyranoside), which are useful in the treatment of cancer in mammals, such as melanoma, squamous cell, myeloma and pranceatic.

  描述了daunomycin的Dimethyfurano类似物，包括(.+-.)-8.alpha.-乙酰基-6,7,8,9-四氢-5,6.beta.,8.beta.,10-四羟基-1,3-二甲基-蒽[2,3-c]-呋喃-4,11-二酮-6-(3-氨基-2,3-6-三脱氧-.alpha.-L-利索-己糖苷)，这些类似物对哺乳动物的癌症治疗具有用处，如黑色素瘤、鳞状细胞癌、骨髓瘤和胰腺癌。
• [EN] THIENO, FURO AND SELENOPHENO-[3,4-C]PYRROLE-4,6-DIONE COPOLYMERS<br/>[FR] COPOLYMÈRES DE THIÉNO, FURO ET SÉLÉNOPHÉNO-[3,4-C]PYRROLE-4,6-DIONE
  申请人：UNIV LAVAL

  公开号：WO2014029014A1

  公开（公告）日：2014-02-27

  Novel photoactive copolymers based on thieno, furo or selenopheno-[3,4- c]pyrrole-4,6-dione-derivative are described herein. More specifically, the photoactive copolymers comprise repeating units of Formula I -[A1-A2]- I wherein A1 is an electron donating unit such as a mono or polycyclic heteroaryl that is unsubstitued or substituted with one or more C1-20-alkyl or C1-20-alkoxy; and A2 is an alkylfuro or alkylselenopheno-[3,4-c]pyrrole-4,6-dione-derivative. The photoactive copolymers are suitable for use in BHJ solar cells.

  本文描述了基于噻吩、呋喃或硒噻吩-[3,4-c]吡咯烷-4,6-二酮衍生物的新型光活性共聚物。更具体地说，这些光活性共聚物包括式I-[A1-A2]-I中的重复单元，其中A1是一个电子给体单元，比如一个未取代或取代一个或多个C1-20烷基或C1-20烷氧基的单环或多环杂环烯基；A2是一个烷基呋喃或烷基硒噻吩-[3,4-c]吡咯烷-4,6-二酮衍生物。这些光活性共聚物适用于BHJ太阳能电池的使用。