Methyl-dibenzyl-allyl-ammonium-chlorid | 98596-59-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methyl-dibenzyl-allyl-ammonium-chlorid
• 英文别名: Dibenzyl-methyl-prop-2-enylazanium;chloride
• CAS: 98596-59-9
• 化学式: C₁₈H₂₂N*Cl
• 分子量: 287.832
• InChiKey: SOGYJWSEXWCJPB-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.02
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Methyl-dibenzyl-allyl-ammonium-chlorid 在 氢氧化钾 作用下， 生成 N-allyl-N-α-methylbenzylamine
  参考文献：
  名称：

  Babayan,A.T. et al., Journal of general chemistry of the USSR, 1963, vol. 33, p. 1727 - 1731

  摘要：

  DOI：

文献信息

• Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes
  申请人：——

  公开号：US20030023089A1

  公开（公告）日：2003-01-30

  Novel heterocyclic compounds which generate chemiluminescence on reaction with a phosphatase enzyme are provided as well as a process for their preparation and intermediates useful therein. The compounds comprise a nitrogen, oxygen or sulfur-containing heterocyclic ring system bearing an exocyclic carbon-carbon double bond. The double bond is further substituted at the distal carbon with a phosphate group and an oxygen or sulfur atom-containing group. Novel compositions further comprising a cationic aromatic compound (CAC) in addition to the heterocyclic phosphate compound are provided. The addition of the CAC in the composition greatly increases the production of chemiluminescence and provides improved detection sensitivity. Compositions further comprising an anionic surfactant and a non-ionic surfactant provide additional improvements in detection sensitivity. The novel chemiluminescent compounds and compositions are useful in methods for producing light and in assays for phosphatase enzymes and enzyme inhibitors and in assays employing enzyme-labeled specific binding pairs.

  本发明提供了产生化学发光的新型杂环化合物，其与磷酸酶酶反应时会产生化学发光，以及用于其制备和有用中间体的方法。该化合物包括带有外向碳-碳双键的氮、氧或硫含杂环环系统。双键在远端碳上进一步取代为一个磷酸酯基团和一个含氧或硫原子的基团。此外，本发明还提供了进一步包括阳离子芳香化合物（CAC）的新型组合物，除了杂环磷酸酯化合物外。在组合物中加入CAC可以大大增加化学发光的产生，并提供改进的检测灵敏度。进一步包括阴离子表面活性剂和非离子表面活性剂的组合物提供了额外的检测灵敏度改进。新型化学发光化合物和组合物在产生光的方法、磷酸酶酶和酶抑制剂的检测方法以及使用酶标记的特异性结合对的检测方法中均有用途。
• Chemiluminescent assay
  申请人：FUJIREBIO INC.

  公开号：EP1113077A2

  公开（公告）日：2001-07-04

  A method for measuring chemiluminescence by which measurement of chemiluminescence can be carried out efficiently and accurately. In this method, an enzyme reaction of a chemiluminescent substrate in the presence of the enzyme carrying out the enzyme reaction and a chemiluminescence enhancer is conducted further in the presence of a chemiluminescence intensity-adjusting agent; and then the resulting chemiluminescence from the reaction product is measured.

  一种测量化学发光的方法，通过该方法可以高效、准确地测量化学发光。在该方法中，化学发光底物在进行酶反应的酶和化学发光增强剂的存在下进行酶反应，然后在化学发光强度调节剂的存在下进一步进行反应；然后测量反应产物产生的化学发光。
• Chemiluminescent substrates
  申请人：Beckman Coulter, Inc.

  公开号：US10703971B2

  公开（公告）日：2020-07-07

  Alkaline phosphatase chemiluminescent substrate formulations are provided exhibiting rapid incubation periods and improved stability for use in immunoassays.

  碱性磷酸酶化学发光底物制剂具有快速孵育期和更高的稳定性，可用于免疫测定。
• Quant-screentm chemiluminescent assays
  申请人：——

  公开号：US20020132364A1

  公开（公告）日：2002-09-19

  Chemiluminescent endogenous enzyme assays which provide for the rapid, simple, and sensitive quantitation of cells directly in microwell cultures by the measurement of endogenous enzyme activity. These endogenous enzyme assays provide homogeneous chemiluminescent formats for measuring cell proliferation, growth inhibition, cell adhesion, cell migration, and cell number quantitation and normalization. Methods and kits employing such assays are also provided.

  化学发光内源酶测定法通过测量内源酶的活性，直接对微孔培养物中的细胞进行快速、简单和灵敏的定量。这些内源酶测定法为细胞增殖、生长抑制、细胞粘附、细胞迁移以及细胞数量的定量和归一化测量提供了均一的化学发光形式。此外，还提供了采用这些检测方法的方法和试剂盒。
• IMPROVED MEMBRANE FOR CHEMILUMINESCENT BLOTTING APPLICATIONS
  申请人：TROPIX, INC.

  公开号：EP0619018A1

  公开（公告）日：1994-10-12