5-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)naphthalen-1-ol | 1046827-69-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)naphthalen-1-ol
• CAS: 1046827-69-3
• 化学式: C₁₈H₂₄O₅
• 分子量: 320.386
• InChiKey: QQQWTYAOKWESOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.99
• 重原子数：
  23.0
• 可旋转键数：
  11.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  57.15
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  5-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)naphthalen-1-ol 、 2-溴乙醇 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以63%的产率得到C₂₀H₂₈O₆
  参考文献：
  名称：

  Tunable threading/dethreading efficiency of the pseudorotaxane by ether chain length

  摘要：

  A series of axles containing the tetraethyl ester calix[4]arene derivative unit and 1,5-dioxynaphthalene (DNP) unit, with different lengths of ether chains, have been synthesized. Complexation of the axles and the cyclobis(paraquat-p-phenylene) (CBPQT(4+)) has been investigated by UV-vis and H-1 NMR spectra. The effect of the length of ether chain on the threading/dethreading processes has also been demonstrated, which indicated that the efficiency of threading/dethreading process decreases with the extension of ether chain. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.015
• 作为产物：
  描述：

  5-(tetrahydro-pyran-2-yloxy)naphthalen-1-ol 、 2-(2-(2-ethoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate 在 potassium carbonate 、 对甲苯磺酸 作用下， 以 N,N-二甲基甲酰胺 、 甲醇 、 二氯甲烷 为溶剂， 反应 16.0h， 以70%的产率得到5-(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)naphthalen-1-ol
  参考文献：
  名称：

  Tunable threading/dethreading efficiency of the pseudorotaxane by ether chain length

  摘要：

  A series of axles containing the tetraethyl ester calix[4]arene derivative unit and 1,5-dioxynaphthalene (DNP) unit, with different lengths of ether chains, have been synthesized. Complexation of the axles and the cyclobis(paraquat-p-phenylene) (CBPQT(4+)) has been investigated by UV-vis and H-1 NMR spectra. The effect of the length of ether chain on the threading/dethreading processes has also been demonstrated, which indicated that the efficiency of threading/dethreading process decreases with the extension of ether chain. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.015