2,4,6-triamino-3,5-difluoropyridine | 1190226-04-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,4,6-triamino-3,5-difluoropyridine
• 英文别名: 3,5-Difluoropyridine-2,4,6-triamine；3,5-difluoropyridine-2,4,6-triamine
• CAS: 1190226-04-0
• 化学式: C₅H₆F₂N₄
• 分子量: 160.126
• InChiKey: XGCWCPRYWCNQJP-UHFFFAOYSA-N

物化性质

• 熔点：
  210-210.5 °C(Solv: chloroform (67-66-3))
• 沸点：
  333.5±37.0 °C(Predicted)
• 密度：
  1.635±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  苯酐 、 2,4,6-triamino-3,5-difluoropyridine 在 苯甲酸 作用下， 反应 3.0h， 以80%的产率得到4-amino-2,6-bis(phthalimido)-3,5-difluoropyridine
  参考文献：
  名称：

  Synthesis and characterization of novel fluorinated pyridine-based polyimides

  摘要：

  New pyridine-containing polyimides based on fluorinated gamma-X-pyridylenediamines (X = H, Cl, NH2, O-linkage) and dianhydride 6FDA were prepared by one-step polycondensation in benzoic acid melt. Molecular weight of the polymers enlarges with an increase of nucleophilicity of the pyridylenediamines and solubility of the macromolecules in the reaction medium. 4,4'-Oxydianiline was used as a co-monomer to prepare high-molecular pyridine-containing PI films with good mechanical properties. The polyimides and co-polyimides obtained are soluble in amide solvents, have good thermal and thermooxidative characteristics. Parameters of the polyimides pyrolysis, which provide consecutive elimination of different elements, were found. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2013.01.037
• 作为产物：
  描述：

  五氟吡啶 在 氨 作用下， 反应 50.0h， 以60%的产率得到2,4,6-triamino-3,5-difluoropyridine
  参考文献：
  名称：

  Direct di- and triamination of polyfluoropyridines in anhydrous ammonia

  摘要：

  Aminodefluorination of polyfluoropyridines (pentafluoro-, 3,5-dichlorotrifluoro-, 3- and 4-chlorotetrafluoro, 2,3,5,6- and 2,3,4,6-tetrafluoro-, 3-chloro-2,4,6-trifluoro-, and 2,4,6-trifluoropyridine) in anhydrous ammonia has been investigated. Temperatures of the second and third amino group introduction into pyridine ring were shown to increase significantly thus ensuring conditions for selective preparation of mono-, di- and, in the case of perhalopyridines as starting compounds, triaminoderivatives with high yield and purity. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2009.02.005