1H,1H,5H-octafluoropentyl phosphoro dichloridite | 65611-15-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1H,1H,5H-octafluoropentyl phosphoro dichloridite
• 英文别名: 2,2,3,3,4,4,5,5-octafluoropentyl phosphorodichloridite；2,2,3,3,4,4,5,5-octafluoropentyl dichlorophosphite；1,1,5-Trihydroperfluoramyl-dichlorphosphit；phosphorodichloridous acid 2,2,3,3,4,4,5,5-octafluoro-pentyl ester；dichloro(2,2,3,3,4,4,5,5-octafluoropentoxy)phosphane
• CAS: 65611-15-6
• 化学式: C₅H₃Cl₂F₈OP
• 分子量: 332.945
• InChiKey: YPQCAZWOIWVJEZ-UHFFFAOYSA-N

物化性质

• 沸点：
  184.0±40.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  1H,1H,5H-octafluoropentyl phosphoro dichloridite 在 磺酰氯 作用下， 以83%的产率得到2,2,3,3,4,4,5,5-Octafluoropentyl Phosphorodichloridate
  参考文献：
  名称：

  Synthesis of ?, ?, ?-trihydropolyfluoroalkyl chlorophosphates by the reaction between ?,?,?-trihydropolyfluoroalkyl phosphites and sulfuryl chloride

  摘要：

  DOI：

  10.1007/bf00962673
• 作为产物：
  描述：

  2,2,3,3,4,4,5,5-八氟-1-戊醇 在 三氯化磷 作用下， 反应 4.0h， 生成 1H,1H,5H-octafluoropentyl phosphoro dichloridite
  参考文献：
  名称：

  Timokhin, B. V.; Kazantseva, M. V.; Chernov, N. F., Russian Journal of General Chemistry, 1995, vol. 65, # 2.2, p. 301

  摘要：

  DOI：

文献信息

• Synthesis and Isomer Composition of 2-Polyfluoroalkoxy-1,3,2-dioxaphospholanes and -phosphinanes
  作者：N. K. Gusarova、S. I. Verkhoturova、S. N. Arbuzova、T. I. Kazantseva、A. I. Albanov、A. M. Nalibaeva、G. K. Bishimbaeva、K. A. Apartsin、V. V. Kireeva、B. A. Trofimov

  DOI：10.1134/s107036321804014x

  日期：2018.4

  Polyfluoroalkanols readily reacted with 2-chloro-1,3,2-dioxaphospholanes and 2-chloro-1,3,2-dioxaphosphinanes in hexane in the presence of triethylamine (-10 to 25A degrees C, 5 h) to give 2-polyfluoroalkoxy-1,3,2- dioxaphospholanes and 2-polyfluoroalkoxy-1,3,2-dioxaphosphinanes in 48-72% yield. The products were found to exist as mixtures of cis and trans isomers with the trans isomer predominating for the phospholanes and cis isomer predominating for the phosphinanes according to the H-1, C-13, F-19, and P-31 NMR data.
• Chauzov, V. A.; Studnev, Yu. N.; Ragulin, L. I., Journal of general chemistry of the USSR, 1989, vol. 59, # 6.1, p. 1146 - 1148
  作者：Chauzov, V. A.、Studnev, Yu. N.、Ragulin, L. I.、Fokin, A. V.

  DOI：——

  日期：——
• Synthesis of Amido- and Diamidophosphites with Polyfluoroalkyl Substituents
  作者：S. F. Malysheva、N. K. Gusarova、N. A. Belogorlova、A. M. Nalibayeva、S. V. Yasko、N. A. Chernysheva、S. I. Verkhoturova、G. K. Bishimbayeva、B. A. Trofimov

  DOI：10.1134/s1070363220020103

  日期：2020.2

  Bis(polyfluoroalkyl) chlorophosphites and polyfluoroalkyl dichlorophosphites react easily with secondary amines (from -40 to -22 degrees C, 1-3 h, CH2Cl2) in the presence or absence of triethylamine to form the corresponding bis(polyfluoroalkyl) diorganylamidophosphites or bis(diorganylamido) polyfluoroalkyl phosphites in the yield of up to 74%. Bis(polyfluoroalkyl) diorganylamidophosphites were also synthesized from diorganylamidodichlorophosphites and polyfluoroalkanols (-25 to -22 degrees C, 2 h, Et3N-CH2Cl2) with a yield of 56-60%.
• Synthesis of Non-Symmetric Functionalized Polyfluoroalkyl Phosphites
  作者：N. K. Gusarova、S. F. Malysheva、N. A. Belogorlova、S. I. Verkhoturova、L. A. Oparina、S. N. Arbuzova、N. A. Chernysheva、A. M. Nalibayeva、G. K. Bishimbayeva、S. V. Yas’ko、B. A. Trofimov

  DOI：10.1134/s1070363220050138

  日期：2020.5

  Two ways for the synthesis of new representatives of non-symmetric organic phosphites with polyfluoroalkyl substituents were developed based on organic dichlorophosphites. The reaction of polyfluoroalkyl dichlorophosphites with allyl alcohol, proceeding at a temperature of -10-22 degrees C (2 h) in the presence of triethylamine, gave diallyl polyfluoroalkyl phosphites in a yield of 75-77%. Under similar conditions (-30-22 degrees C, 2-4 h, Et3N), alkyl (or aryl) dichlorophosphites reacted with polyfluoroalkanols to form alkyl (or aryl) bis(polyfluoroalkyl) phosphites (yield 56-67%). Unlike diallylpolyfluoroalkyl- and alkylbis(polyfluoroalkyl) phosphites, arylbis(polyfluoroalkyl) phosphites are symmetrized under storage conditions (room temperature, inert atmosphere), forming the corresponding triaryl- and tris(polyfluoroalkyl) phosphites.
• CHAUZOV, V. A.;STUDNEV, YU. N.;RAGULIN, L. I.;USTINOV, A. A.;FOKIN, A. V., IZV. AN CCCP. CEP. XIM.,(1988) N 1, 146-149
  作者：CHAUZOV, V. A.、STUDNEV, YU. N.、RAGULIN, L. I.、USTINOV, A. A.、FOKIN, A. V.

  DOI：——

  日期：——