1,2,3-trimethyl-1-indanol | 241155-66-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 二苯并环庚烯
• 英文名称: 1,2,3-trimethyl-1-indanol
• 英文别名: 1-Hydroxy-1.2.3-trimethyl-indan；1,2,3-Trimethyl-indan-1-ol；1,2,3-trimethyl-2,3-dihydroinden-1-ol
• CAS: 241155-66-8
• 化学式: C₁₂H₁₆O
• 分子量: 176.258
• InChiKey: UOLYPCDTDAGXFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,2,3-trimethyl-1-indanol 在 正丁基锂 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 正己烷 、 甲苯 为溶剂， 反应 24.0h， 生成 1-trimethylsilyl-1,2,3-trimethylindene
  参考文献：
  名称：

  用于间间特定苯乙烯聚合的新型茚基钛催化剂

  摘要：

  一系列多甲基取代的茚的以及allylindene，Ñ -propylindene，ñ -丁-1- enylindene，和Ñ -butylindene已经以良好的收率制备。经由中间有机锂配合物与氯代三甲基硅烷的反应，将取代的茚满转化为三甲基甲硅烷基衍生物。由三甲基甲硅烷基衍生物与TiCl 4的反应以优异的产率合成了相应的钛配合物。当被甲基铝氧烷活化时，钛络合物被评估为甲苯溶液中的苯乙烯聚合催化剂。通常，催化活性随每个另外的甲基取代基而降低。间特异性很高（90-95％）。

  DOI：

  10.1016/s0022-328x(99)00095-9
• 作为产物：
  描述：

  (E)-2-甲基-2-丁烯酰氯 在 三氯化铝 作用下， 以 乙醚 为溶剂， 生成 1,2,3-trimethyl-1-indanol
  参考文献：
  名称：

  用于间间特定苯乙烯聚合的新型茚基钛催化剂

  摘要：

  一系列多甲基取代的茚的以及allylindene，Ñ -propylindene，ñ -丁-1- enylindene，和Ñ -butylindene已经以良好的收率制备。经由中间有机锂配合物与氯代三甲基硅烷的反应，将取代的茚满转化为三甲基甲硅烷基衍生物。由三甲基甲硅烷基衍生物与TiCl 4的反应以优异的产率合成了相应的钛配合物。当被甲基铝氧烷活化时，钛络合物被评估为甲苯溶液中的苯乙烯聚合催化剂。通常，催化活性随每个另外的甲基取代基而降低。间特异性很高（90-95％）。

  DOI：

  10.1016/s0022-328x(99)00095-9

文献信息

• New cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions
  申请人：Evonik Degussa GmbH

  公开号：EP1894938A1

  公开（公告）日：2008-03-05

  The invention is directed to a phosphine compound represented by general formula (1) wherein R' and R" independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R' and R" are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.

  该发明涉及一种由通式（1）表示的膦化合物 其中 R'和R"独立地选自烷基、环烷基和2-呋喃基，或者R'和R"结合在一起与磷原子形成至少含有3个碳原子的碳-磷单环或碳-磷双环；所述烷基基团、环烷基基团和碳-磷单环未取代或取代，所述取代包括来自烷基、环烷基、芳基、烷氧基和芳氧基基团中至少一个基团的选择； Cps是部分取代或完全取代的环戊二烯-1-基团，包括导致融合环系统的取代，当环戊二烯-1-基团不是融合环系统的一部分或是茚基团的一部分时，环戊二烯-1-基团的1-位取代是强制的。还声明了这些膦化合物作为催化反应中的配体以及这些膦化合物的制备的用途。
• CYCLOPENTADIENYL, INDENYL OR FLUORENYL SUBSTITUTED PHOSPHINE COMPOUNDS AND THEIR USE IN CATALYTIC REACTIONS
  申请人：Plenio Herbert

  公开号：US20090253907A1

  公开（公告）日：2009-10-08

  A phosphine compound represented by general formula (1) wherein R′ and R″ independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R′ and R″ are joined together to form with the phosphorous atom a carbon-phosphorous monocycle including at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cp s is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. These phosphines can be used as ligands in catalytic reactions.

  一种磷化合物，其通式表示为（1），其中R'和R''独立地选择烷基，环烷基和2-呋喃基基团，或者R'和R''与磷原子结合形成至少包括3个碳原子的碳-磷单环或碳-磷双环；烷基基团，环烷基基团和碳-磷单环未经取代或被至少一种从烷基，环烷基，芳基，烷氧基和芳氧基基团组成的基团取代；Cps是部分取代或完全取代的环戊二烯-1-基基团，包括导致融合环系统的取代，当环戊二烯-1-基基团不是融合环系统的一部分或是一个茚基基团的一部分时，必须在环戊二烯-1-基基团的1位进行取代。这些磷化物可以用作催化反应中的配体。
• New Cyclopentadienyl, Indenyl or Fluorenyl Substituted Phosphine Compounds and their Use in Catalytic Reactions
  申请人：PLENIO Herbert

  公开号：US20120245348A1

  公开（公告）日：2012-09-27

  Disclosed herein are phosphine compounds represented by the general formula (4): and corresponding phosphonium salts represented by the general formula (4a): Also disclosed are processes for the preparation of these phosphines and phosphonium salts as well as their use as ligands in catalytic reactions.

  本文披露了由一般式（4）表示的膦化合物和由一般式（4a）表示的相应膦鎵鹽，同时还披露了制备这些膦化合物和膦鎵鹽的过程，以及它们作为催化反应中的配体的用途。
• New Cyclopentadienyl, Indenyl or Fluorenyl Substituted Phosphine Compounds and Their Use in Catalytic Reactions
  申请人：Evonik Degussa GmbH

  公开号：US20140058101A1

  公开（公告）日：2014-02-27

  The invention is directed to a phosphine compound represented by general formula (1) wherein R′ and R″ independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R′ and R″ are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cp s is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.

  本发明涉及一种磷化合物，其通式表示为（1），其中R'和R"独立地选择为烷基，环烷基和2-呋喃基基团，或者R'和R"与磷原子结合形成至少包含3个碳原子的碳-磷单环或碳-磷双环；烷基基团，环烷基基团和碳-磷单环未被取代或被至少一种从烷基，环烷基，芳基，烷氧基和芳氧基基团中选择的基团取代；Cp是部分取代或完全取代的环戊二烯-1-基基团，包括导致融合环系统的取代，当环戊二烯-1-基基团不是融合环系统的一部分或是茚基团的一部分时，必须在环戊二烯-1-基基团的1位进行取代。还声明了这些磷化物作为催化反应中的配体以及这些磷化物的制备的用途。
• Cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions
  申请人：Evonik Degussa GmbH

  公开号：US08969624B2

  公开（公告）日：2015-03-03

  The invention is directed to a phosphine compound represented by general formula (1) wherein R′ and R″ independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R′ and R″ are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.

  本发明涉及一种磷化合物，其通式（1）表示，其中R′和R″独立地选择自烷基、环烷基和2-呋喃基基团，或R′和R″与磷原子结合形成至少含有3个碳原子的碳磷单环或碳磷双环；烷基基团、环烷基基团和碳磷单环可以未经取代或被至少一种选择自烷基、环烷基、芳基、烷氧基和芳氧基基团的基团取代；Cps是部分取代或完全取代的环戊二烯-1-基基团，包括导致融合环系统的取代物，在环戊二烯-1-基基团不是融合环系统的一部分或是吲哚基团的一部分时，必须在其1-位置进行取代。还声明了将这些磷化合物用作催化反应中的配体以及制备这些磷化合物的用途。