4-(3-methylphenyl)-4-trimethylsiloxy-1-butene | 1162681-61-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(3-methylphenyl)-4-trimethylsiloxy-1-butene
• 英文别名: 4-(m-tolyl)-4-trimethylsiloxy-1-butene
• CAS: 1162681-61-9
• 化学式: C₁₄H₂₂OSi
• 分子量: 234.414
• InChiKey: HKXCUTXVVKFDHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.46
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  4-(3-methylphenyl)-4-trimethylsiloxy-1-butene 在 盐酸 、 水 作用下， 以 甲醇 为溶剂， 生成 1-(3-methylphenyl)but-3-en-1-ol
  参考文献：
  名称：

  Mesoporous aluminosilicate-catalyzed allylation of carbonyl compounds and acetals

  摘要：

  A mesoporous aluminosilicate (Al-MCM-41) was found to be an effective heterogeneous catalyst for the reaction of both carbonyl compounds and acetals with allylsilanes to afford the corresponding homoallyl silyl ethers and homoallyl alkyl ethers, respectively. Both the mesoporous structure and the presence of aluminum moiety were indispensable for the high catalytic activity of Al-MCM-41. Moreover, Al-MCM-41 could catalyze the reaction of acetals chemoselectively in the presence of the corresponding carbonyl compounds. The solid acid catalyst Al-MCM-41 could be recovered easily by filtration and could be reused three times without a significant loss of catalytic activity. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.01.055
• 作为产物：
  描述：

  3-甲基苯甲醛 、 烯丙基三甲基硅烷 在 Al-MCM-41 (Si/Al=26) 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以70%的产率得到4-(3-methylphenyl)-4-trimethylsiloxy-1-butene
  参考文献：
  名称：

  Mesoporous aluminosilicate-catalyzed allylation of aldehydes with allylsilanes

  摘要：

  Mesoporous aluminosilicate (Al-MCM-41) was found to catalyze the allylation of both aromatic and aliphatic aldehydes with allylsilanes although amorphous silica-alumina or mesoporous silicates (MCM-41, SBA-15) Could not catalyze the reaction under the same reaction conditions. The solid acid catalyst Al-MCM-41 could be reused three times without significant loss of activity. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.04.002

文献信息

• Highly atom economical uncatalysed and I2-catalysed silylation of phenols, alcohols and carbohydrates, using HMDS under solvent-free reaction conditions (SFRC)
  作者：Marjan Jereb

  DOI：10.1016/j.tet.2012.03.040

  日期：2012.5

  An uncatalysed silylation of phenols, regardless on the aggregate state and nature of the substituents with 0.55 equiv of HMDS under solvent-free reaction conditions (SFRC) at room temperature is reported. Sterically hindered phenols, carbohydrates and most of the alcohols additionally required a catalytic amount (up to 2 mol%) of iodine. The reaction protocol is very simple; obtaining a pure product, particularly of uncatalysed reactions, was frequently a completely solvent-free process. (C) 2012 Elsevier Ltd. All rights reserved.