triethylammonium azide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: triethylammonium azide
• 英文别名: triethylazanium;azide
• 化学式: C₆H₁₆N*N₃
• 分子量: 144.22
• InChiKey: YIHJHCFUGYYAKW-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  7.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  triethylammonium azide 、 六氟丙烯 以 further solvent(s) 为溶剂， 生成 pentafluoro-1-propenylazide
  参考文献：
  名称：

  Fluoroazirines. Synthesis and Polymerization

  摘要：

  DOI：

  10.1021/ja01094a032
• 作为试剂：
  描述：

  环氧氯丙烷 在 triethylammonium azide 作用下， 以 乙醚 为溶剂， 反应 4.0h， 以98%的产率得到1-叠氮基-3-氯-2-丙醇
  参考文献：
  名称：

  Maksikova, A. V.; Serebryakova, E. S.; Shcherbakov, V. V., Journal of Organic Chemistry USSR (English Translation), 1989, vol. 25, # 7.2, p. 1371 - 1375

  摘要：

  DOI：

文献信息

• 6.alpha., .beta.-Substituted penicillin derivatives
  申请人：Merck & Co., Inc.

  公开号：US04035359A1

  公开（公告）日：1977-07-12

  Novel 6-methoxy and 6-thioalkyl-6-acylamido-penicillanic acids and their non-toxic pharmaceutically-acceptable salts, esters and amides which are useful as antibiotics. The products are prepared by treating an ester of 6-substituted-6-aminopenicillanic acid with an acylating agent followed by removal of the ester group. Also disclosed are novel intermediates.

  新型的6-甲氧基和6-硫代烷基-6-酰胺基-青霉烷酸及其无毒的药用可接受盐、酯和酰胺，可用作抗生素。这些产品是通过将6-取代-6-氨基青霉烷酸酯与酰化剂处理后去除酯基而制备的。还披露了新型中间体。
• Derivatives of 6-aminopenicillanic acid
  申请人：Merck & Co., Inc.

  公开号：US04071529A1

  公开（公告）日：1978-01-31

  Novel 6-methoxy and 6-thioalkyl-6-acylamidopenicillanic acids and their non-toxic pharmaceutically-acceptable salts, esters and amides which are useful as antibiotics. The products are prepared by treating an ester of 6-substituted-6-aminopenicillanic acid with an acylating agent followed by removal of the ester group. Also disclosed are novel intermediates.

  新型的6-甲氧基和6-硫代烷基-6-酰胺基青霉烷酸及其无毒的药用可接受盐、酯和酰胺，可用作抗生素。这些产品是通过将6-取代-6-氨基青霉烷酸酯与酰化剂处理，然后去除酯基而制备的。还披露了新型中间体。
• [EN] METHOD FOR PREPARATION OF CERTAIN 1,5 DISUBSTITUTED TETRAZOLES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE CERTAINS TÉTRAZOLES 1,5 DISUBSTITUÉS
  申请人：LONZA AG

  公开号：WO2016142364A1

  公开（公告）日：2016-09-15

  The invention discloses a method for the preparation of certain 1,5 disubstituted tetrazole and similar compounds starting from certain thioacetamides, which ultimately allows the preparation of these certain 1,5 disubstituted tetrazoles from readily available compounds such as acetophenone and similar compounds.

  该发明揭示了一种从某些硫代乙酰胺起始制备某些1,5-二取代四唑和类似化合物的方法，最终允许从可轻易获得的化合物（如苯乙酮和类似化合物）制备这些某些1,5-二取代四唑。
• Alkylene oxide polymerisation catalysts
  申请人：MITSUI TOATSU CHEMICALS, INCORPORATED

  公开号：EP0763555A2

  公开（公告）日：1997-03-19

  A catalyst for the polymerization of an alkylene oxide compound is composed of a phosphazene compound or a phosphazenium salt which is derived from the phosphazene compound and an active hydrogen compound. A poly(alkylene oxide) can be efficiently produced by polymerizing the alkylene oxide compound in the presence of the catalyst and, when the catalyst is composed of the phosphazene compound, the active hydrogen compound. The poly(alkylene oxide) contains no residual metal components and compared with those produced using conventional amine-base catalysts, has also significantly improved odor.

  用于环氧亚烷基化合物聚合的催化剂由磷氮化合物或由磷氮化合物衍生的磷氮鎓盐和活性氢化合物组成。在催化剂和活性氢化合物（当催化剂由磷氮化合物组成时）存在的情况下，通过聚合环氧亚烷基化合物可以有效地生产聚环氧亚烷基化合物。聚环氧烷不含残留金属成分，与使用传统胺基催化剂生产的聚环氧烷相比，气味也有明显改善。
• PROCESS FOR PRODUCING 2' -(1H-TETRAZOL-5-YL)-BIPHENYL-4-CARBALDEHYDE
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1666471A1

  公开（公告）日：2006-06-07

  The present invention provides a process for producing 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde which comprises reacting 2'-cyanobiphenyl-4-carbaldehyde with a salt of azide; a process for producing a highly pure crystal of 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde which comprises reacting 2'-cyanobiphenyl-4-carbaldehyde with a salt of azide, obtaining a crystal of 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde, dissolving said crystal obtained and recrystallizing a highly pure crystal in tetrahydrofuran; and the like. According to the present process, 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde which is useful as a synthetic intermediate of medicines can be produced in a short process at high yield and high purity.

  本发明提供了一种生产2'-(1H-四唑-5-基)联苯-4-甲醛的工艺，该工艺包括使2'-氰基联苯-4-甲醛与叠氮盐反应；一种生产高纯度 2'-(1H-四唑-5-基)联苯-4-甲醛晶体的工艺，包括使 2'-氰基联苯-4-甲醛与叠氮化物盐反应，得到 2'-(1H-四唑-5-基)联苯-4-甲醛晶体，溶解得到的晶体并在四氢呋喃中重结晶出高纯度晶体；以及类似工艺。 根据本工艺，可在短时间内生产出高产率和高纯度的 2'-(1H-四唑-5-基)联苯-4-甲醛，该物质可用作药物合成中间体。