pentafluorophenyl acrylamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: pentafluorophenyl acrylamide
• 英文别名: N-(2,3,4,5,6-pentafluorophenyl)prop-2-enamide
• 化学式: C₉H₄F₅NO
• 分子量: 237.129
• InChiKey: FFIQBGKMFJIHFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-phenoxyacetamide 、 pentafluorophenyl acrylamide 在 potassium phosphate 、 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以18%的产率得到
  参考文献：
  名称：

  铑（III）在氧化还原-中性条件下由CH活化N-苯氧基乙酰胺引发的烯烃的碳氨化反应

  摘要：

  N-烷氧基丙烯酰胺与R - III催化的N-苯氧基乙酰胺通过C-H官能化和酰胺基团的转移在无外部氧化剂的条件下进行偶联，从而以原子经济的方式提供了无环烯烃碳氨基化产物。对这种转变的机理研究表明，N-烷氧基丙烯酰胺中的酰胺基在此C–C / C–N键形成反应中起关键作用。该方法提供了在温和条件下构建邻酪氨酸衍生物的高效方法。

  DOI：

  10.1021/acs.orglett.6b00616
• 作为产物：
  描述：

  2,3,4,5,6-五氟苯胺 、 丙烯酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以25%的产率得到pentafluorophenyl acrylamide
  参考文献：
  名称：

  铑（III）在氧化还原-中性条件下由CH活化N-苯氧基乙酰胺引发的烯烃的碳氨化反应

  摘要：

  N-烷氧基丙烯酰胺与R - III催化的N-苯氧基乙酰胺通过C-H官能化和酰胺基团的转移在无外部氧化剂的条件下进行偶联，从而以原子经济的方式提供了无环烯烃碳氨基化产物。对这种转变的机理研究表明，N-烷氧基丙烯酰胺中的酰胺基在此C–C / C–N键形成反应中起关键作用。该方法提供了在温和条件下构建邻酪氨酸衍生物的高效方法。

  DOI：

  10.1021/acs.orglett.6b00616

文献信息

• Polymer compound, film obtained by hardening this polymer compound and electronic device comprising this film
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US10676554B2

  公开（公告）日：2020-06-09

  A polymer compound comprising a repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group, a repeating unit having at least one group selected from the group consisting of a hydroxy group and a carboxy group and a repeating unit represented by the following formula (1), wherein the content of the repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group in the polymer compound is 1% by mol or more and 30% by mol or less when the total content of all repeating units contained in the above-described polymer compound is taken as 100% by mol: in the formula (1), R2, R2 and R3 each independently represent a hydrogen atom or a methyl group.

  一种聚合物化合物，包括 具有至少一个选自封端异氰酸酯基团和封端异硫氰酸酯基团的基团的重复单元、 具有至少一个选自羟基和羧基的基团的重复单元，以及 由下式(1)表示的重复单元，其中 具有至少一个选自封端异氰基和封端异硫氰基的基团的重复单元在聚合物化合物中的含量为 1%（以摩尔计）或以上，当上述聚合物化合物中所含所有重复单元的总含量为 100%（以摩尔计）时，其含量为 30%（以摩尔计）或以下： 在式 (1) 中，R2、R2 和 R3 各自独立地代表氢原子或甲基。
• ALPHA, BETA-UNSATURATED SULFONES, SULFOXIDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES AND ACYLSULFINAMIDES AND THERAPEUTIC USES THEREOF
  申请人：Temple University of the Commonwealth System of Higher Education

  公开号：EP1773310A2

  公开（公告）日：2007-04-18
• POLYMER COMPOUND, FILM OBTAINED BY HARDENING THIS POLYMER COMPOUND AND ELECTRONIC DEVICE COMPRISING THIS FILM
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20190211123A1

  公开（公告）日：2019-07-11

  A polymer compound comprising a repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group, a repeating unit having at least one group selected from the group consisting of a hydroxy group and a carboxy group and a repeating unit represented by the following formula (1), wherein the content of the repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group in the polymer compound is 1% by mol or more and 30% by mol or less when the total content of all repeating units contained in the above-described polymer compound is taken as 100% by mol: in the formula (1), R 2 , R 2 and R 3 each independently represent a hydrogen atom or a methyl group.
• CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF
  申请人：ISP INVESTMENTS LLC

  公开号：US20190382519A1

  公开（公告）日：2019-12-19

  This application provides cross-linked block copolymers comprising at least one block comprising repeating units derived from monomers comprising lactam and acryloyl moieties. The application further provides compositions comprising the block copolymers and applications thereof in various industrial areas including personal care. The application furthermore provides Pickering emulsion compositions comprising the block copolymers.
• [EN] ALPHA, BETA-UNSATURATED SULFONES, SULFOXIDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES AND ACYLSULFINAMIDES AND THERAPEUTIC USES THEREOF<br/>[FR] SULFONES, SULFOXYDES, SULFONIMIDES, SULFINIMIDES, ACYLSULFONAMIDES ET ACYLSULFINAMIDES ALPHA, BETA-INSATURES ET LEURS UTILISATIONS THERAPEUTIQUES
  申请人：GHER EDUCATION TEMPLE UNIVERSI

  公开号：WO2006025924A2

  公开（公告）日：2006-03-09

  α,β-Unsaturated sulfones, sulfoxides, sulfonimides, sulfinimides, acylsulfonamides and acylsulfinamides of Formula I: wherein R1 R2, M1 M2, L, E1, E2, Q1, Q2 and n are as defined herein, are useful as anti-angiogenesis agents, as agents for treatment of age related senile dementia, and as antiproliferative agents including, for example, as anticancer agents.