1,1,3-三氯丙烷 | 20395-25-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 1,1,3-三氯丙烷
• 英文名称: 1,1,3-trichloropropane
• 英文别名: 1,1,3-Trichlor-propan
• CAS: 20395-25-9
• 化学式: C₃H₅Cl₃
• mdl: MFCD19231975
• 分子量: 147.432
• InChiKey: URWHLZCXYCQNSY-UHFFFAOYSA-N

物化性质

• 熔点：
  -58.98°C
• 沸点：
  145.55°C
• 密度：
  1.3544
• 溶解度：
  可溶于氯仿、乙酸乙酯

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  6
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903199000

反应信息

• 作为反应物：
  描述：

  1,1,3-三氯丙烷 在 sodium iodide 作用下， 以 丙酮 为溶剂， 生成 1,1-dichloro-3-iodopropane
  参考文献：
  名称：

  Kruglova, N. V.; Petrova, N. A.; Freidlina, R. Kh., Journal of general chemistry of the USSR, 1990, vol. 60, # 5, p. 922 - 926

  摘要：

  DOI：
• 作为产物：
  描述：

  1,3-dichloropropanol 在 五氯化磷 作用下， 以 Petroleum ether 为溶剂， 以22%的产率得到1,1,3-三氯丙烷
  参考文献：
  名称：

  Luminogenic and fluorogenic compounds and methods to detect molecules or conditions

  摘要：

  公开号：

  EP2277872B1

文献信息

• ESTERS OF AMINO CARBOXYLIC ACIDS AND A PROCESS TO PREPARE THEM
  申请人：NOURYON CHEMICALS INTERNATIONAL B.V.

  公开号：US20210198182A1

  公开（公告）日：2021-07-01

  A process to prepare an amine-functional ester of an amino carboxylic acid includes the step of reacting a polyol of the formula (I) HO-A-OH  (I) where A is a carbon chain with about 2 to about 36 carbon atoms that is aliphatic linear or branched, saturated or unsaturated, or aromatic, or CH 2 CH(OH)CH 2 , CH 2 C(CH 2 OH) 2 CH 2 , CH 2 C(CH 2 OH)(CH 3 )CH 2 , CH 2 C(CH 2 OH)(CH 2 CH 3 )CH 2 , p-tetrahydrofuran, erythritol or an ester of di- or tricarboxylic acids with ethylene or propylene glycol, and wherein A can optionally be alkoxylated or reacted with hydroxy carboxylic acids, with an aminocarboxylic acid of formula II or its cyclic amide of the formula III, where m is an integer of about 1 to about 8 in formula II and about 3 to about 8 in formula III, each R independently is hydrogen or a C1-C4 alkyl group, or CH 2 CH 2 COOH, or CH 2 COOH, or (CH 2 ) 4 NH 2 , in the presence of a Brønsted-Lowry acid.

  制备氨基羧酸酯的过程包括以下步骤：将具有以下式(I)的多元醇与式(II)的氨基羧酸或其环状酰胺的反应，其中在式(I)中，A是一个碳链，含有大约2至大约36个碳原子，可以是脂肪族的直链或支链、饱和或不饱和、芳香族，或CH2CH(OH)CH2、CH2C(CH2OH)2CH2、CH2C(CH2OH)(CH3)CH2、CH2C(CH2OH)(CH2CH3)CH2、对四氢呋喃、赤藓醇或二酸或三酸酯与乙二醇或丙二醇的酯，其中A可以选择性地与烷氧基化或与羟基羧酸反应，在Brønsted-Lowry酸存在下进行。
• [EN] PROCESS FOR THE PREPARATION OF 2,3,3,3 TETRAFLUOROPROPENE<br/>[FR] PROCÉDÉ DE SYNTHÈSE DE 2,3,3,3-TÉTRAFLUOROPROPÈNE
  申请人：ARKEMA FRANCE

  公开号：WO2012052797A1

  公开（公告）日：2012-04-26

  The present invention provides a process for preparing 2, 3, 3, 3-tetrafluoropropene, comprising the following steps: (a) catalytic reaction of 1, 1, 1, 2, 3-pentachloropropane and/or 1, 1, 2, 2, 3-pentachloropropane with HF into product 2- chloro-3, 3, 3-trifluoropropene; (b) catalytic reaction of the thus-obtained 2-chloro-3, 3, 3-trifluoropropene into 2,3,3, 3-tetrafluoropropene.

  本发明提供了一种制备2,3,3,3-四氟丙烯的方法，包括以下步骤：(a) 1,1,1,2,3-五氯丙烷和/或1,1,2,2,3-五氯丙烷与氢氟酸的催化反应，生成产物2-氯-3,3,3-三氟丙烯；(b) 将得到的2-氯-3,3,3-三氟丙烯进行催化反应，得到2,3,3,3-四氟丙烯。
• Method of Converting a Brominated Hydrocarbon to a Chlorinated Hydrocarbon
  申请人：Eagle US 2 LLC

  公开号：US20210047250A1

  公开（公告）日：2021-02-18

  The present invention provides a method of converting a brominated hydrocarbon to a chlorinated hydrocarbon that involves contacting together the brominated hydrocarbon and a chlorinated ion exchange resin that has a water content of less than or equal to 30 percent by weight, based on the total weight of the chlorinated ion exchange resin and the water. The brominated hydrocarbon includes at least one replaceable bromo group, where each replaceable bromo group is independently covalently bonded to an sp 3 hybridized carbon. Contact between the brominated hydrocarbon and the chlorinated ion exchange resin results in replacement of at least one replaceable bromo group of the brominated hydrocarbon with a chloro group, and correspondingly conversion of at least a portion of the brominated hydrocarbon to the chlorinated hydrocarbon.

  本发明提供了一种将溴化碳氢转化为氯化碳氢的方法，涉及将溴化碳氢和含水量小于或等于30重量百分比的氯化离子交换树脂一起接触。其中，所述含水量是基于氯化离子交换树脂和水的总重量。溴化碳氢包括至少一个可替换的溴基团，其中每个可替换的溴基团独立地共价键合到一个sp3杂化碳上。溴化碳氢与氯化离子交换树脂之间的接触导致将溴化碳氢中的至少一个可替换的溴基团替换为氯基，并相应地将至少一部分溴化碳氢转化为氯化碳氢。
• [EN] PROCESS FOR THE PRODUCTION OF CHLORINATED PROPENES<br/>[FR] PROCÉDÉ DE PRODUCTION DE PROPÈNES CHLORÉS
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2013022677A1

  公开（公告）日：2013-02-14

  Processes for the production of chlorinated propenes are provided. The present processes make use of a feedstock comprising 1,2,3-trichloropropane and chlorinates the 1,1,2,3-tetrachloropropane generated by the process prior to a dehydrochlorination step. Production of the less desirable pentachloropropane isomer, 1,1,2,3,3-pentachloropropane, is thus minimized. The present processes provide better reaction yield as compared to conventional processes that require dehydrochlorination of 1,1,2,3-tetrachloropropane prior to chlorinating the same. The present process can also generate anhydrous HCl as a byproduct that can be removed from the process and used as a feedstock for other processes, while limiting the production of waste water, thus providing further time and cost savings.

  提供了生产氯代丙烯的工艺。目前的工艺利用包含1,2,3-三氯丙烷的原料，并在去氢氯化步骤之前氯化由该过程产生的1,1,2,3-四氯丙烷。因此，生产较不理想的五氯丙烷异构体1,1,2,3,3-五氯丙烷被最小化。与需要在氯化相同物质之前对1,1,2,3-四氯丙烷进行去氢氯化的传统工艺相比，目前的工艺提供了更好的反应产率。目前的工艺还可以生成无水HCl作为副产品，可以从工艺中去除并用作其他工艺的原料，同时限制废水的产生，从而提供进一步的时间和成本节约。
• [EN] PROCESS FOR THE PRODUCTION OF CHLORINATED PROPENES<br/>[FR] PROCÉDÉ POUR LA PRODUCTION DE PROPÈNES CHLORÉS
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2012166394A1

  公开（公告）日：2012-12-06

  Processes for the production of chlorinated propenes are provided. The present processes make use of 1,2-dichloropropane, a by-product in the production of chlorohydrin, as a low cost starting material, alone or in combination with 1,2,3-trichloropropane. The present processes can also generate anhydrous HCl as a byproduct that can be removed from the process and used as a feedstock for other processes, providing further time and cost savings. Finally, the processes are advantageously conducted in the liquid phase, thereby presenting additional savings as compared to conventional, gas phase processes.

  提供了生产氯代丙烯的工艺。目前的工艺利用1,2-二氯丙烷，这是氯水合物生产中的副产品，作为低成本的起始原料，单独或与1,2,3-三氯丙烷结合使用。目前的工艺还可以产生无水HCl作为副产品，可以从工艺中去除并用作其他工艺的原料，进一步节省时间和成本。最后，这些工艺有利地在液相中进行，因此与传统的气相工艺相比，提供了额外的节省。

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