毒理性
使用期间总结：监测婴儿是否困倦、体重增长是否充足以及发育里程碑，特别是在年轻的、仅接受母乳喂养的婴儿中，以及在使用抗惊厥药或精神药物组合时。由于关于母乳喂养期间使用加巴喷丁的已发表经验非常有限，因此可能更倾向于使用其他药物，特别是在哺乳新生儿或早产儿时。
对哺乳婴儿的影响：一位母亲在服用加巴喷丁24毫克，随后每天20毫克的同时哺乳。在10名在母亲服用每天1000至3000毫克左乙拉西坦期间哺乳的4至23天大的新生儿中没有报告不良反应。其中一位母亲还在服用每天30毫克的加巴喷丁、每天45毫克的氯巴占和每天600毫克的奥卡西平。
对泌乳和母乳的影响：截至修订日期，没有找到相关的已发表信息。
◉ Summary of Use during Lactation:Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. Because there is very limited published experience with tiagabine during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
◉ Effects in Breastfed Infants:One mother breastfed her infant while taking tiagabine 24 mg and then 20 mg daily.
No adverse effects were reported in 10 newborns who were 4 to 23 days old who were breastfed during maternal intake of levetiracetam 1000 to 3000 mg daily. One mother was also taking tiagabine 30 mg daily, clobazam 45 mg daily and oxcarbazepine 600 mg daily.
◉ Effects on Lactation and Breastmilk:Relevant published information was not found as of the revision date.
来源:Drugs and Lactation Database (LactMed)
