2-(3,4-dibenzyloxyphenyl)ethyl acetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(3,4-dibenzyloxyphenyl)ethyl acetate
• 英文别名: 3,4-Bis(phenylmethoxy)benzeneethanol 1-Acetate；2-[3,4-bis(phenylmethoxy)phenyl]ethyl acetate
• 化学式: C₂₄H₂₄O₄
• 分子量: 376.452
• InChiKey: XTJSCNCYAYBSRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(3,4-dibenzyloxyphenyl)ethyl acetate 在 palladium on activated charcoal 1,4-环己二烯 作用下， 以75%的产率得到3,4-二羟基苯乙醇醋酸
  参考文献：
  名称：

  Antioxidant Activity of Hydroxytyrosol Acetate Compared with That of Other Olive Oil Polyphenols

  摘要：

  Hydroxytyrosol acetate was synthesized, and the antioxidant activity of this olive oil component was assessed in comparison with that of other olive oil components, namely hydroxytyrosol, oleuropein, 3,4-DHPEA-EA, and alpha -tocopherol in bulk oil and oil-in-water emulsions. The activity of the compounds was also assessed by scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol, oleuropein, or 3,4-DHPEA-EA but it had a radical scavenging activity similar to that of cr-tocopherol. In oil, the antioxidant activity of hydroxytyrosol acetate was much higher than that of alpha -tocopherol or oleuropein, but in an emulsion S,4-DHPEA-EA and alpha -tocopherol were more effective as antioxidants than hydroxytyrosol acetate. The antioxidant activity of hydroxytyrosol acetate was rather similar to that of hydroxytyrosol in oil and emulsions despite the difference in DPPH radical scavenging activity.

  DOI：

  10.1021/jf000537w
• 作为产物：
  描述：

  羟基酪醇 在 吡啶 、 N,N'-二环己基碳二亚胺 作用下， 反应 72.0h， 生成 2-(3,4-dibenzyloxyphenyl)ethyl acetate
  参考文献：
  名称：

  Antioxidant Activity of Hydroxytyrosol Acetate Compared with That of Other Olive Oil Polyphenols

  摘要：

  Hydroxytyrosol acetate was synthesized, and the antioxidant activity of this olive oil component was assessed in comparison with that of other olive oil components, namely hydroxytyrosol, oleuropein, 3,4-DHPEA-EA, and alpha -tocopherol in bulk oil and oil-in-water emulsions. The activity of the compounds was also assessed by scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol, oleuropein, or 3,4-DHPEA-EA but it had a radical scavenging activity similar to that of cr-tocopherol. In oil, the antioxidant activity of hydroxytyrosol acetate was much higher than that of alpha -tocopherol or oleuropein, but in an emulsion S,4-DHPEA-EA and alpha -tocopherol were more effective as antioxidants than hydroxytyrosol acetate. The antioxidant activity of hydroxytyrosol acetate was rather similar to that of hydroxytyrosol in oil and emulsions despite the difference in DPPH radical scavenging activity.

  DOI：

  10.1021/jf000537w