3-N-N-diallylaminopropionic acid | 124929-55-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-N-N-diallylaminopropionic acid
• 英文别名: 3-(diallylamino)propanoic acid；3-[Bis(prop-2-enyl)azaniumyl]propanoate
• CAS: 124929-55-1
• 化学式: C₉H₁₅NO₂
• mdl: MFCD06208065
• 分子量: 169.224
• InChiKey: DUUFVJCLNRNOTQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.444
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-N-N-diallylaminopropionic acid 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 2-(1-Allyl-1H-pyrrol-3-ylmethylsulfanyl)-pyridine
  参考文献：
  名称：

  The use of acyl derivatives of -hydroxy-2-thiopyridone in a simple synthesis of pyrrolidines and tetrahydrofurans

  摘要：

  DOI：

  10.1016/s0040-4039(00)99175-5
• 作为产物：
  描述：

  prop-2-enyl 3-[bis(prop-2-enyl)amino]propanoate 在 碘 作用下， 以 乙二醇 为溶剂， 反应 0.58h， 以78%的产率得到3-N-N-diallylaminopropionic acid
  参考文献：
  名称：

  快速而有选择性 脱酰作用 烯丙基醚和 酯类 在聚乙二醇400中使用碘

  摘要：

  一个简单而有选择性的 脱酰作用 烯丙基醚和 酯类 在聚乙二醇400中使用碘（10 mol％）作为绿色反应 溶剂描述。反应在室温下用各种芳基/烷基烯丙基醚和酯类产量高到极好。本方法包括便宜的催化剂，后处理容易，反应条件良好，选择性高。

  DOI：

  10.1039/c1gc15153c

文献信息

• WRINKLE-IMPROVING AGENT
  申请人：Shiseido Company, Limited

  公开号：EP1941861A1

  公开（公告）日：2008-07-09

  The invention provides a novel wrinkle-improving agent that has an effect of improving wrinkles, that does not entail problems of safety or pain even when applied to the skin, and that contains a very safe substance as an active component. A discovery was made that N-benzoyl-β-alanine, other specific β-alanine derivatives, and salts thereof have a wrinkle-improving effect, whereby a wrinkle-improving agent containing as an active component one, two, or more types of compounds selected from the group composed of these specific β-alanine derivatives and the salts thereof was developed.

  该发明提供了一种新型的改善皱纹的剂，具有改善皱纹的效果，即使应用于皮肤也不会带来安全或疼痛问题，并且包含一种非常安全的物质作为活性成分。发现N-苯甲酰-β-丙氨酸、其他特定的β-丙氨酸衍生物及其盐具有改善皱纹的效果，因此开发了一种改善皱纹的剂，其活性成分包含从这些特定的β-丙氨酸衍生物及其盐组成的群体中选择的一种、两种或更多种化合物。
• Polymers based on n,n-diallylamine derivatives their production and use
  申请人：Becker Stefan

  公开号：US20070004889A1

  公开（公告）日：2007-01-04

  The present invention relates to processes for the preparation of novel polymers starting from the reaction of diallylamine or diallylamine derivatives with olefinically unsaturated compounds within the framework of a Michael addition and subsequent free-radical polymerization of the Michael adducts, if appropriate in the presence of further free-radically polymerizable compounds. The invention also provides the corresponding Michael adducts of diallylamine and its derivatives, and also the use of the novel polymers.

  本发明涉及一种从二烯基胺或二烯基胺衍生物与烯丙基不饱和化合物进行迈克尔加成反应并随后自由基聚合迈克尔加成物的制备过程，如有必要，在进一步自由基聚合性化合物的存在下。本发明还提供了二烯基胺及其衍生物的相应迈克尔加成物，并提供了新型聚合物的使用。
• Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin
  申请人：Kaminuma Mikiko

  公开号：US20120232111A1

  公开（公告）日：2012-09-13

  The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin—inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and further provides an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent comprises one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof. The external composition for skin comprises the one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/ameliorating agent.

  本发明提供了一种角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂，具有诸如角化过度抑制、毛孔收缩或粗糙肌肤抑制/减轻等功能，不会引起感觉刺激等安全问题，非常安全，还提供了一种外用皮肤组成物，其中添加了具有上述功能的化合物。该角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂包括从β-丙氨酸衍生物和其盐的群组中选择的一种或多种化合物。该外用皮肤组成物包括上述β-丙氨酸衍生物和其盐中的一种或多种作为上述角化过度抑制剂、毛孔收缩剂或粗糙肌肤预防/改善剂。
• DISPOSABLE APPLICATOR FOR SKIN CARE COMPOSITIONS
  申请人：——

  公开号：US20010003565A1

  公开（公告）日：2001-06-14

  The present invention provides an applicator for applying and distributing a substance onto a target surface. The applicator comprises a substantially planar sheet of compressible, conformable material having opposed first and second surfaces and an interior region between said first and second surfaces. The sheet of material has a thickness between the first and second surfaces which decreases when the sheet of material is subjected to an externally-applied force in a direction substantially normal to the first surface. The applicator further includes at least one discrete reservoir extending inwardly of the first surface into the interior of the sheet of material which is at least partially filled with a substance and at least one discrete aperture formed in the first surface which is in fluid communication with the reservoir. Compression of the sheet of material via an externally-applied force substantially normal to said first surface expresses product from the aperture and translational motion of the first surface relative to a target surface applies and distributes said product onto the target surface. In a preferred embodiment, a plurality of apertures are associated with corresponding reservoirs forming a delivery zone near one end of a hand-held applicator, and the sheet material is preferably resilient both in compression and in bending to conform to irregular target surfaces. A wide variety of substances are contemplated, including particularly skin care compositions for skin that are susceptible to body exudates, moisture, or irritants. Other embodiments include a single reservoir feeding a plurality of apertures.

  本发明提供了一种用于在目标表面涂抹和分布物质的涂抹器。涂抹器包括一个基本平面的可压缩、可保形材料薄片，该薄片具有相对的第一和第二表面以及所述第一和第二表面之间的内部区域。材料片在第一和第二表面之间有一个厚度，当材料片在第一表面的大致法线方向上受到外力作用时，厚度会减小。涂抹器还包括至少一个从第一表面向内延伸到材料片内部的离散贮存器，该贮存器至少部分填充有物质，以及至少一个在第一表面形成的与贮存器流体相通的离散孔。通过基本与所述第一表面法线方向一致的外部作用力压缩材料片，将产品从孔中挤出，第一表面相对于目标表面的平移运动将所述产品施加并分配到目标表面上。在一个优选的实施方案中，多个开孔与相应的储液器相连，形成一个靠近手持涂抹器一端的输送区，片状材料最好在压缩和弯曲时都具有弹性，以适应不规则的目标表面。可以考虑使用多种物质，特别是用于易受身体渗出物、湿气或刺激物影响的皮肤的护肤组合物。其他实施方案包括一个贮液器，贮液器上有多个孔。
• Absorbent article having a stable skin care composition
  申请人：——

  公开号：US20020165508A1

  公开（公告）日：2002-11-07

  The present invention relates to an absorbent article having a stable skin care composition disposed on its skin-contacting surface. The skin care composition is readily transferable to the skin via normal contact, wearer motion, and/or body heat. Importantly, the skin care composition contains at least one skin care ingredient imparting visible skin benefits to the skin upon transfer to the skin and at least one rheological agent for stabilizing the composition such that agglomeration, stratification and/or settling of the composition are minimized. The present invention also relates to a process for making the absorbent articles having a stable skin care composition disposed thereon.

  本发明涉及一种吸收性物品，该物品与皮肤接触的表面上有一种稳定的护肤组合物。护肤组合物可通过正常接触、穿戴者的运动和/或体温很容易地转移到皮肤上。重要的是，护肤组合物含有至少一种护肤成分，可在转印到皮肤上时给皮肤带来明显的护肤效果，还含有至少一种流变剂，用于稳定组合物，使组合物的结块、分层和/或沉淀降至最低。本发明还涉及一种用于制造具有稳定护肤组合物的吸水性物品的工艺。