2-hydroxy-N-[2-hydroxy-3-[(2-hydroxybenzoyl)amino]propyl]benzamide | 132758-05-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxy-N-[2-hydroxy-3-[(2-hydroxybenzoyl)amino]propyl]benzamide
• CAS: 132758-05-5
• 化学式: C₁₇H₁₈N₂O₅
• 分子量: 330.34
• InChiKey: XGHQSRQDFWKMIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  119
• 氢给体数：
  5
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-hydroxy-N-[2-hydroxy-3-[(2-hydroxybenzoyl)amino]propyl]benzamide 、 hydrated Er(III) thiocyanate 在 三乙胺 作用下， 以 甲醇 、 乙腈 为溶剂， 反应 48.0h， 以61%的产率得到
  参考文献：
  名称：

  对称a酸酯配体支持的手性镧系四面体簇的合成，结构和磁性

  摘要：

  摘要通过Ln（SCN）3的水热反应组装了两个分子式为[Ln4（μ4-O）（HL）3（SCN）4（H2O）2]的团簇（Ln = Dy（1），Er（2））。三乙胺存在下，水合物和对称的酰胺化物H3L配体（2-羟基-N- [2-羟基-3-[（2-羟基苯甲酰基）氨基]丙基]苯甲酰胺）。X射线晶体学分析显示1和2是同构的，并且是具有μ4-O中心的Ln4四面体核心的四核，其中四个晶体学上不等价的镧系元素离子在扭曲的封端八面体几何结构中均七配位。值得注意的是，两个簇均显示出手性，该手性是由螺旋扭曲的配体的配位作用诱导的。已经研究了1和2的磁性。

  DOI：

  10.1016/j.ica.2017.05.010

文献信息

• New binucleating amido ligands, synthesis and structures of copper(II) and manganese(III) complexes
  作者：Karen Bertoncello、Gary D. Fallon、Keith S. Murray

  DOI：10.1016/s0277-5387(00)84192-3

  日期：1990.1

  Abstract New binucleating ligands containing μ-alkoxo backbones and amido-pyridyl or amido-phenol “end” groups have been synthesized. The syntheses and structures of mononuclear CuII and binuclear (CuIICuII and MnIIIMnIII) complexes are described. The crystal structure of a novel doubly-bridged MnIIIMnIII complex shows that each six-coordinate manganese is bridged by endogenous μ-alkoxo and exogenous

  摘要合成了含有μ-烷氧基骨架和酰胺基-吡啶基或酰胺基-苯酚“端”基的新的双核配体。描述了单核CuII和双核（CuIICuII和MnIIIMnIII）配合物的合成和结构。新型双桥MnIIIMnIII配合物的晶体结构表明，每个六配位锰均由内源性μ-烷氧基和外源性μ-乙酰基桥接。为了获得更高的氧化态金属物种，将需要化学或电化学氧化。
• Structure and Properties of Copper(II), Manganese(III), and Iron(III) Complexes with Potentially Pentaanionic Heptadentate Ligands Including Alkoxido, Amido, and Phenoxido Donors
  作者：Liliana Stoicescu、Carine Duhayon、Laure Vendier、Ana Tesouro‐Vallina、Jean‐Pierre Costes、Jean‐Pierre Tuchagues

  DOI：10.1002/ejic.200900791

  日期：2009.12

  The synthesis and characterization of copper(II), manganese(III), and iron(III) complexes [Cu 2 (L 1 )(OAc)Cs 2 -(MeOH) 2 ] n (1), [Mn 2 (H 3 L 1 ) 2 (OMe) 2 ]·2MeOH (2), [Fe 2 (H 3 L 1 ) 2 -(Hpz) 4 ](ClO 4 ) 2 ·2CH 3 CN (3), and [Fe 2 (H 3 L 3 ) 2 (OMe) 2 ]· 8MeOH (4) of potentially pentaanionic heptadentate ligands, 2-hydroxy-N-2-hydroxy-3-[(2-hydroxybenzoyl)amino]propyl)benzamide (H 5 L 1 ) and

  铜 (II)、锰 (III) 和铁 (III) 配合物 [Cu 2 (L 1 )(OAc)Cs 2 -(MeOH) 2 ] n (1)、[Mn 2 (H 3) 的合成和表征L 1 ) 2 (OMe) 2 ]·2MeOH (2)、[Fe 2 (H 3 L 1 ) 2 -(Hpz) 4 ](ClO 4 ) 2 ·2CH 3 CN (3)、[Fe 2 (H) 3 L 3 ) 2 (OMe) 2 ]·8MeOH (4) 的潜在五阴离子七齿配体，2-羟基-N-2-羟基-3-[(2-羟基苯甲酰基)氨基]丙基)苯甲酰胺(H 5 L 1 )和2-羟基-N-3-羟基-5-[(2-羟基苯甲酰基)氨基]戊基}苯甲酰胺(H 5 L 3 )。已经确定了这些配合物的晶体结构和磁性。在配合物 1 中，配体 H 5 L 1 充当七齿、完全去质子化的配体 [L 1 ] 5- 。在配合物 2、3 和 4 中，H 5 L 1
• Structure and Properties of Dinuclear Manganese(III) Complexes with Pentaanionic Pentadentate Ligands Including Alkoxo, Amido, and Phenoxo Donors
  作者：Liliana Stoicescu、Aurélie Jeanson、Carine Duhayon、Ana Tesouro-Vallina、Athanassios K. Boudalis、Jean-Pierre Costes、Jean-Pierre Tuchagues

  DOI：10.1021/ic062398r

  日期：2007.8.1

  Doubly bridged mu-alkoxo-mu-X (X = pyrazolato or acetato) dinuclear Mn-III complexes of 2-hydroxy-N-2-hydroxy-3-[(2-hydroxybenzoyl)amino]propyl}benzamide) (H5L1) and 2-hydroxy-N-2-hydroxy-4-[(2-hydroxybenzoyl)amino]-butyl}benzamide (H5L2), [Mn-2(L)(pz)(MeOH)(4)]center dot xMeOH (1, L = L-1, x = 0.5; 2, L = L-2, x = 0; Hpz = pyrazole) and [Mn-2(L-1)(OAc)(MeOH)(4)] (3), have been prepared, and their structure and magnetic properties have been studied. The X-ray diffraction analysis of 1 (C24.5H34Mn2N4O9.5, triclinic, P-1, a = 12.2050(7) angstrom, b = 12.7360(8) angstrom, c = 19.2780(10) angstrom, alpha = 99.735(5)degrees, beta = 96.003(4)degrees, gamma = 101.221(5)degrees, V = 2867.6(3) angstrom(3), Z = 4), 2 (C25H34Mn2N4O9, triclinic, P1, a = 9.4560(5) angstrom, b = 11.0112(5) angstrom, c = 13.8831(6) angstrom, alpha = 90.821(4)degrees, beta = 92.597(4)degrees, gamma = 93.403(4)degrees, V = 1441.29(12) angstrom(3), Z = 2), and 3 (C23H32Mn2N2O11, triclinic, P1, a = 10.511(5) angstrom, b = 11.713(5) angstrom, c = 13.135(5) angstrom, alpha = 64.401(5)degrees, beta = 74.000(5)degrees, gamma = 66.774(5)degrees, V = 1329.3(10) angstrom(3), Z = 2) revealed that all complexes consist of dinuclear units which are further extended into 1D (1 and 3) and 2D (2) supramolecular networks via hydrogen-bonding interactions, Magnetic susceptibility data evidence antiferromagnetic interactions for all three complexes: J = -3.6 cm(-1), D approximate to 0 cm(-1), g = 1.93 (1); J = -2.7 cm(-1), D = 0.8 cm(-1), g = 1.93 (2); J = -4.9 cm(-1), D = 3.8 cm(-1), g = 1.95 (3).
• Syntheses, structures and magnetic properties of chiral lanthanide tetrahedral clusters supported by symmetrical amidate ligands
  作者：Shuang-Yan Lin、Baodong Sun、Zhikun Xu

  DOI：10.1016/j.ica.2017.05.010

  日期：2017.8

  core, in which four crystallographically unequivalent lanthanide ions are all seven-coordinated in distorted capped octahedron geometries. Significantly, both clusters show chirality that is induced by coordination of spirally twisted ligands. The magnetic properties of 1 and 2 have been investigated. Both clusters do not exhibit slow magnetic relaxation that may be ascribed to the effect of the symmetry

  摘要通过Ln（SCN）3的水热反应组装了两个分子式为[Ln4（μ4-O）（HL）3（SCN）4（H2O）2]的团簇（Ln = Dy（1），Er（2））。三乙胺存在下，水合物和对称的酰胺化物H3L配体（2-羟基-N- [2-羟基-3-[（2-羟基苯甲酰基）氨基]丙基]苯甲酰胺）。X射线晶体学分析显示1和2是同构的，并且是具有μ4-O中心的Ln4四面体核心的四核，其中四个晶体学上不等价的镧系元素离子在扭曲的封端八面体几何结构中均七配位。值得注意的是，两个簇均显示出手性，该手性是由螺旋扭曲的配体的配位作用诱导的。已经研究了1和2的磁性。