2-(4-甲基-1,3-二恶烷-4-基)乙醇 | 2018-45-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 中文名称: 2-(4-甲基-1,3-二恶烷-4-基)乙醇
• 英文名称: 4-(β-hydroxyethyl)-4-methyl-1,3-dioxane
• 英文别名: 4-methyl-4-(2-hydroxyethyl)-1,3-dioxane；4-hydroxyethyl-4-methyl-1,3-dioxane；2-(4-methyl-[1,3]dioxan-4-yl)-ethanol；4-Methyl-4-<2-hydroxy-aethyl>-1,3-dioxan；4-Methyl-4-hydroxyaethyl-1,3-dioxan；4-Methyl-4-aethylol-1,3-dioxan；4-(2-Hydroxyethyl)-4-methyl-1,3-dioxane；2-(4-methyl-1,3-dioxan-4-yl)ethanol
• CAS: 2018-45-3
• 化学式: C₇H₁₄O₃
• 分子量: 146.186
• InChiKey: OAVPPFPSHUKFPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  2-(4-甲基-1,3-二恶烷-4-基)乙醇 在 吡啶 、 氯化亚砜 、 硝酸 、 potassium carbonate 、 sodium nitrite 、 Katamin AB 作用下， 以 丙酮 为溶剂， 反应 8.0h， 生成 甲瓦龙酸内酯
  参考文献：
  名称：

  Synthesis of mevalonolactone from 4-(?-hydroxyethyl)-4-methyl-1,3-dioxane

  摘要：

  DOI：

  10.1007/bf00605192

文献信息

• [EN] POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES<br/>[FR] POLYMÈRES PRÉPARÉS À PARTIR DE LA MÉVALONOLACTONE ET DE SES DÉRIVÉS
  申请人：VISOLIS INC

  公开号：WO2016077555A1

  公开（公告）日：2016-05-19

  Described herein polymer precursor compounds (aka polymer building blocks) of derived from biobased compounds, and specifically biobased mevalonolactone and its related derivatives. Through oxidation these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols and polyamides, as well as precursors for glycidyl esters and omega-alkenyl esters. Through reduction, these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols, polycarbonates, as well as precursors for glycidyl ethers and omega-alkenyl ethers. Through nucleophilic ring opening and/or amidation, these biobased precursors can be reacted to yield building blocks for polyester polyols, chain-extender for polyurethanes, or polyester-amides.

  本文描述了从生物基化合物中衍生的聚合物前体化合物（又称聚合物构建模块），特别是生物基美伐酮内酯及其相关衍生物。通过氧化，这些生物基前体可以被反应生成（不饱和的）聚酯、聚酯多元醇和聚酰胺的构建模块，以及环氧酯和ω-烯基酯的前体。通过还原，这些生物基前体可以被反应生成（不饱和的）聚酯、聚酯多元醇、聚碳酸酯的构建模块，以及环氧醚和ω-烯基醚的前体。通过亲核环开和/或酰胺化，这些生物基前体可以被反应生成聚酯多元醇的构建模块，聚氨酯的扩链剂，或聚酯酰胺。
• POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES
  申请人：Visolis, Inc.

  公开号：US20160130389A1

  公开（公告）日：2016-05-12

  Described herein polymer precursor compounds (aka polymer building blocks) of derived from biobased compounds, and specifically biobased mevalonolactone and its related derivatives. Through oxidation these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols and polyamides, as well as precursors for glycidyl esters and omega-alkenyl esters. Through reduction, these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols, polycarbonates, as well as precursors for glycidyl ethers and omega-alkenyl ethers. Through nucleophilic ring opening and/or amidation, these biobased precursors can be reacted to yield building blocks for polyester polyols, chain-extender for polyurethanes, or polyester-amides.

  本文描述了从生物基化合物中衍生出的聚合物前体化合物（又称聚合物构建块），特别是生物基美瓦酮内酯及其相关衍生物。通过氧化，这些生物基前体可以反应产生（不饱和）聚酯、聚酯多元醇和聚酰胺的构建块，以及环氧酯和ω-烯基酯的前体。通过还原，这些生物基前体可以反应产生（不饱和）聚酯、聚酯多元醇、聚碳酸酯的构建块，以及环氧醚和ω-烯基醚的前体。通过亲核环开和/或酰胺化，这些生物基前体可以反应产生聚酯多元醇、聚氨酯的链延长剂，或聚酯酰胺的构建块。
• Devekki, A. B.; Idlis, G. S.; Ogorodnikov, S. K., Journal of Organic Chemistry USSR (English Translation), 1981, vol. 17, p. 1998 - 1999
  作者：Devekki, A. B.、Idlis, G. S.、Ogorodnikov, S. K.

  DOI：——

  日期：——
• Devekki, A. V.; Koshelev, Yu. N.; Malov, Yu. I., Journal of general chemistry of the USSR, 1983, vol. 53, # 11, p. 2392 - 2393
  作者：Devekki, A. V.、Koshelev, Yu. N.、Malov, Yu. I.、Devekki, A. B.、Strashnova, G. M.

  DOI：——

  日期：——
• Oxidation of 4-methyl-4-(2-hydroxyethyl)-1,3-dioxane to 2-hydroxy-2-methylglutaric acid
  作者：A. B. Devekki、A. N. Egor'kov、I. B. Blanshtein、A. V. Devekki、G. S. Idlis

  DOI：10.1007/bf00474057

  日期：1988.9