(5-Dodecyloxy-naphthalen-1-yloxy)-acetyl chloride | 545390-72-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (5-Dodecyloxy-naphthalen-1-yloxy)-acetyl chloride
• 英文别名: 2-(5-dodecoxynaphthalen-1-yl)oxyacetyl chloride
• CAS: 545390-72-5
• 化学式: C₂₄H₃₃ClO₃
• 分子量: 404.977
• InChiKey: OJEOATXXIIQKHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.28
• 重原子数：
  28.0
• 可旋转键数：
  15.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  三乙烯四胺 、 (5-Dodecyloxy-naphthalen-1-yloxy)-acetyl chloride 在 吡啶 、 4-二甲氨基吡啶 作用下， 以 氯仿 为溶剂， 以80%的产率得到2-(5-Dodecyloxy-naphthalen-1-yloxy)-N-{2-[2-(5-dodecyloxy-naphthalen-1-yloxy)-acetylamino]-ethyl}-N-[2-([2-(5-dodecyloxy-naphthalen-1-yloxy)-acetyl]-{2-[2-(5-dodecyloxy-naphthalen-1-yloxy)-acetylamino]-ethyl}-amino)-ethyl]-acetamide
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p
• 作为产物：
  描述：

  (5-dodecyloxy-naphthalene-1-yloxy)-acetic acid 在 草酰氯 、 N,N-二甲基甲酰胺 作用下， 以 苯 为溶剂， 反应 12.0h， 生成 (5-Dodecyloxy-naphthalen-1-yloxy)-acetyl chloride
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p