4-Amino-4-ethyl-heptadien-(1,6)

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-Amino-4-ethyl-heptadien-(1,6)
• 英文别名: 1-ethyl-1-(2-propenyl)-3-butenylamine；4-ethylhepta-1,6-dien-4-amine
• 化学式: C₉H₁₇N
• mdl: MFCD03002115
• 分子量: 139.241
• InChiKey: VZUWDRNNZFYLBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.555
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  ammonium chloride 、 丙腈 、 烯丙基溴化镁 在 盐酸 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 以34%的产率得到1-ethyl-1-(2-propenyl)-3-butenyl isocyanate
  参考文献：
  名称：

  Isosteric antiherpes peptide derivatives II

  摘要：

  本文披露的是公式A--B--D--CH.sub.2 CH{CH.sub.2 C(O)R.sup.1 }C(O)--NHCH{CR.sup.2 (R.sup.3)COOH}C(O)--E中的肽类似化合物，其中A是一个末端基团，例如一个可选择取代的苯基烷酰基，B是一个N-甲基氨基酸残基；或者A和B一起形成饱和或不饱和的烷基氨基甲酰基；D是一个氨基酸残基；R.sup.1是烷基，环烷基，单取代或双取代氨基；R.sup.2是氢，R.sup.3是苯基烷基，或者R.sup.2和R.sup.3连接形成环烷基；E是一个末端单元，例如，一个烷基氨基或一个单价氨基酸基团，如NHCH(烷基)C(O)OH。这些衍生物可用于治疗疱疹感染。

  公开号：

  US05846941A1

文献信息

• Isosteric antiherpes peptide derivatives
  申请人：Bio-Mega/Boehringer Ingelheim Research Inc.

  公开号：US05574015A1

  公开（公告）日：1996-11-12

  Disclosed herein are peptide derivatives of the formula A-B-D-CH.sub.2 CHCH.sub.2 C(O)R.sup.1 }C(O)-NHCHCR.sup.2 (R.sup.3)COOH}C(O)-E wherein A is a terminal group, for example an optionally substituted phenylalkanoyl, and B is a N-methyl amino acid residue; or A and B together form a saturated or unsaturated alkylaminocarbonyl; D is an amino acid residue; R.sup.1 is alkyl, cycloalkyl, a monosubstituted or a disubstituted amino; R.sup.2 is hydrogen or alkyl and R.sup.3 is alkyl, or R.sup.2 is hydrogen and R.sup.3 is phenylalkyl, or R.sup.2 and R.sup.3 are joined to form a cycloalkyl; and E is a terminal unit, for example, an alkylamino or a monovalent amino acid radical such as NHCH(alkyl)C(O)OH. The derivatives are useful for treating herpes infections.

  本公开揭示的是公式A-B-D-CH.sub.2 CHCH.sub.2 C(O)R.sup.1 }C(O)-NHCHCR.sup.2 (R.sup.3)COOH}C(O)-E的肽衍生物，其中A是末端基团，例如可选择取代的苯基丙酰基，B是N-甲基氨基酸残基；或者A和B一起形成饱和或不饱和的烷基氨基甲酰基；D是氨基酸残基；R.sup.1是烷基，环烷基，单取代或双取代氨基；R.sup.2是氢或烷基，R.sup.3是烷基，或者R.sup.2是氢而R.sup.3是苯基丙基，或者R.sup.2和R.sup.3连接形成环烷基；E是末端单元，例如烷基氨基或NHCH(烷基)C(O)OH等单价氨基酸基团。这些衍生物可用于治疗疱疹感染。
• AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS
  申请人：Gamez-Garcia Manuel

  公开号：US20100226868A1

  公开（公告）日：2010-09-09

  Novel ampholytic ter-polymers comprising at least an ethylenically unsaturated cationic monomer, a monomer containing a carboxylic acid or sulfonic acid group and diallyamine or derivative are claimed. Further, the ter-polymers may be used in personal care or personal washing compositions optionally in the presence of conditioning agents such as silicone, fatty amines, fatty amine oxides and fatty quaternaries and/or various benefit agents. The ter-polymer compositions are especially useful in the treatment of keratin-containing substrates. Keratin substrates include, but are not limited to, animal and human hair, skin and nails.

  本发明涉及一种新型两性离子聚合物，其中包含至少一种乙烯基不饱和阳离子单体、一种含有羧酸或磺酸基团的单体以及二烯基胺或其衍生物。此外，该聚合物可以用于个人护理或个人清洁组合物中，可选地与调理剂（如硅油、脂肪胺、脂肪胺氧化物和脂肪季铵盐）和/或各种功效剂一起使用。该聚合物组合物在处理含角蛋白底物方面特别有用。角蛋白底物包括但不限于动物和人类的头发、皮肤和指甲。
• METHOD FOR PRODUCING COPOLYMER OF DIALLYLAMINE AND SULFUR DIOXIDE
  申请人：Nitto Boseki Co., Ltd

  公开号：EP2578618A1

  公开（公告）日：2013-04-10

  Provided is a process for producing a copolymer of a diallylamine and sulfur dioxide which copolymer has a higher molecular weight and water-solubility than that obtained by a conventional production process by copolymerizing the diallylamine and sulfur dioxide in the presence of an acid and a radical polymerization initiator in a polar solvent.

  本发明提供了一种生产二烯丙基胺和二氧化硫共聚物的工艺，该共聚物的分子量和水溶性均高于传统生产工艺，其方法是在极性溶剂中，在酸和自由基聚合引发剂的存在下，将二烯丙基胺和二氧化硫进行共聚。
• ARYLCYCLOBUTENES
  申请人：Rohm and Haas Electronic Materials LLC

  公开号：EP3184571A1

  公开（公告）日：2017-06-28

  Arylcyclobutene polymers having improved physical properties, such as elongation, are provided. Compositions and methods for coating such arylcyclobutene polymers are also provided.

  提供了具有更好物理性能（如伸长率）的芳基环丁烯聚合物。此外，还提供了涂覆此类芳基环丁烯聚合物的组合物和方法。
• COPOLYMER OF DIALLYLAMINE AND SULFUR DIOXIDE, AND METHOD FOR PRODUCING SAME
  申请人：Nitto Boseki Co., Ltd

  公开号：EP3363846A1

  公开（公告）日：2018-08-22

  Provided are a copolymer of a diallylamine and sulfur dioxide having a high molecular weight and a low content amount of impurities such as halogens, and a production method with which it is possible to produce such a copolymer relatively simply and at low cost. This problem is solved by: a copolymer having a weight-average molecular weight of 150,000 or higher and a degree of polymerization of 1000 or higher determined by GPC measurement, the copolymer being obtained by copolymerizing sulfur dioxide and a sulfonic acid salt or alkyl sulfate salt of a diallylamine having a specific structure; and a method for producing a copolymer, the method having a step for copolymerizing sulfur dioxide and a sulfonic acid salt or alkyl sulfate salt of a diallylamine having a specific structure in ethylene glycol or in propylene glycol monomethyl ether.

  本文提供了一种分子量高、卤素等杂质含量低的二烯丙基胺与二氧化硫的共聚物，以及一种可以相对简单、低成本地生产这种共聚物的生产方法。解决这一问题的方法是一种共聚物，其重量平均分子量为 150,000 或更高，聚合度为 1000 或更高，通过 GPC 测量测定，该共聚物由二氧化硫和具有特定结构的二烯丙基胺的磺酸 盐或烷基硫酸盐共聚得到；以及一种生产共聚物的方法，该方法的一个步骤是在乙二醇或丙二醇单甲醚中使二氧化硫和具有特定结构的二烯丙基胺的磺酸盐或烷基硫酸盐共聚。