sodium 4-phenylphenoxide | 3645-61-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: sodium 4-phenylphenoxide
• 英文别名: sodium 4-phenylphenolate；sodium phenyl phenoxide；biphenyl-4-ol; sodium biphenylolate-(4)；Biphenyl-4-ol; Natrium-biphenylolat-(4)；Natrium-biphenylolat-(4)；p-Phenylphenol sodium；sodium;4-phenylphenolate
• CAS: 3645-61-2
• 化学式: C₁₂H₉O*Na
• 分子量: 192.193
• InChiKey: PJOIPAGEBPZNSD-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.57
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  23.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2916399090

反应信息

• 作为反应物：
  描述：

  sodium 4-phenylphenoxide 在 PEG-400 、 三氯氧磷 作用下， 以 水 、 甲苯 为溶剂， 反应 1.0h， 以96%的产率得到tri([1,1'-biphenyl]-4-yl) phosphate
  参考文献：
  名称：

  Krishnakumar, V. K., Synthetic Communications, 1984, vol. 14, # 2, p. 189 - 196

  摘要：

  DOI：
• 作为产物：
  描述：

  对羟基联苯 在 sodium 、 苯 作用下， 生成 sodium 4-phenylphenoxide
  参考文献：
  名称：

  Xenyl Esters and Ethers

  摘要：

  DOI：

  10.1021/ja01306a042

文献信息

• Importance of Open Structure of Nonmetal Based Catalyst in Hydrogen Bond Promoted Methanolysis of Activated Amide: Structure Dynamics between Monomer and Dimer Enabling Recombinant Covalent, Dative, and Hydrogen Bonds
  作者：Shunsuke Oishi、Junichi Yoshimoto、Susumu Saito

  DOI：10.1021/ja9029494

  日期：2009.7.1

  aminoorganoboron (AOB) compounds that involved a recombinant of covalent, dative, and hydrogen bonds. A combination process occurred via reorganizing elements and bonds between the two major structures (open and closed), which were chemically switchable through precise adjustment of either acidic or basic conditions. The structural dynamics favoring an open structure seem to be more important for catalysis, as represented

  我们揭示了隐藏在一系列氨基有机硼 (AOB) 化合物背后的结构动力学，这些化合物涉及共价键、配位键和氢键的重组。通过重组两个主要结构（开放和封闭）之间的元素和键，发生了一个组合过程，这两个主要结构可以通过精确调整酸性或碱性条件进行化学切换。有利于开放结构的结构动力学似乎对催化更为重要，如活化酰胺的甲醇分解。
• Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives
  作者：C. S. Rooney、W. C. Randall、K. B. Streeter、C. Ziegler、E. J. Cragoe、H. Schwam、S. R. Michelson、H. W. R. Williams、E. Eichler

  DOI：10.1021/jm00359a015

  日期：1983.5

  3-hydroxy-1H-pyrrole-2,5-dione derivatives has been prepared and studied as inhibitors of glycolic acid oxidase (GAO). Compounds possessing large lipophilic 4-substituents are, in general, potent, competitive inhibitors of porcine liver GAO in vitro. Methylation of the nitrogen or the 3-hydroxy substituent reduced potency dramatically, indicating the requirement for the two acidic functions on the 1H-pyrrole-2

  已经制备了一系列广泛的新颖的4-取代的3-羟基-1H-吡咯-2，5-二酮衍生物，并作为乙醇酸氧化酶（GAO）的抑制剂进行了研究。具有大的亲脂性4-取代基的化合物通常是猪肝GAO体外的有效竞争性抑制剂。氮或3-羟基取代基的甲基化显着降低了效能，表明需要1H-吡咯-2,5-二酮核上的两个酸性功能。在大鼠肝脏灌注研究中，使用三种代表性化合物，观察到浓度依赖性抑制[1-14C]乙醇酸酯向[14C]草酸酯的转化。长期口服喂食乙二醇的大鼠4-（4'-溴[1,1'-联苯] -4-基）衍生物（83）在58天内可显着降低草酸尿水平期。
• Retracted Article: Synthesis and characterization of Co/Ti layered double hydroxide and its application as a photocatalyst for degradation of aqueous Congo Red
  作者：Priyadarshi Roy Chowdhury、Krishna G. Bhattacharyya

  DOI：10.1039/c5ra19106h

  日期：——

  Hydrothermally synthesized 2 : 1 Co/Ti LDH exhibits remarkable visible light assisted degradation of Congo Red (∼99.7%) to simple and less toxic molecules than the parent carcinogenic dye.

  水热合成的2:1 Co/Ti LDH表现出显著的可见光辅助降解刚果红（约99.7%），使其转化为比母体致癌染料更简单且毒性更小的分子。
• A convenient enantioselective synthesis of trans-2-aryloxycyclohexan-1-ols using pig liver acetone powder (PLAP) as biocatalyst
  作者：Deevi Basavaiah、Peddinti Rama Krishna、Tirumala K Bharathi

  DOI：10.1016/0957-4166(95)00029-o

  日期：1995.2

  Pig liver acetone powder (PLAP) has been used as a biocatalyst for enantioselective hydrolysis of racemic trans-1-acetoxy-2-aryloxycyclohexannes to produce the resulting (R,R)-2-aryloxycyclohexan-1-ols upto >99% enantiomeric purities. (R,R)-Selectivity in this hydrolysis of racemic trans-2-aryloxycyclohexyl acetates was explained on the basis of Jones' three dimensional active site-model.

  猪肝丙酮粉（PLAP）已被用作外消旋反式-1-乙酰氧基-2-芳氧基环己烯的对映选择性水解的生物催化剂，以产生高达> 99％的对映体纯度的生成的（R，R）-2-芳氧基环己-1-醇。根据琼斯的三维活性位点模型解释了外消旋反式-2-芳氧基环己基乙酸酯在水解中的（R，R）-选择性。
• Tuning Reactivity and Electronic Properties through Ligand Reorganization within a Cerium Heterobimetallic Framework
  作者：Jerome R. Robinson、Zachary Gordon、Corwin H. Booth、Patrick J. Carroll、Patrick J. Walsh、Eric J. Schelter

  DOI：10.1021/ja410688w

  日期：2013.12.18

  Cerium compounds have played vital roles in organic, inorganic, and materials chemistry due to their reversible redox chemistry between trivalent and tetravalent oxidation states. However, attempts to rationally access molecular cerium complexes in both oxidation states have been frustrated by unpredictable reactivity in cerium(III) oxidation chemistry. Such oxidation reactions are limited by steric

  铈化合物由于其在三价和四价氧化态之间的可逆氧化还原化学，在有机、无机和材料化学中发挥了重要作用。然而，由于铈（III）氧化化学中不可预测的反应性，试图合理地获得两种氧化态的分子铈配合物的尝试受到了挫败。这种氧化反应受到金属离子位阻饱和的限制，这会导致电子转移的高能量激活势垒。另一种方法是使用稀土/碱金属/1,1'-BINOLate (REMB) 异质双金属框架实现的，该框架在二级配位范围内使用氧化还原惰性金属来控制配体重组。