N-(1,3-苯并噻唑-2-基硫基)-1-丙胺 | 66552-53-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: N-(1,3-苯并噻唑-2-基硫基)-1-丙胺
• 英文名称: N-propyl-2-benzothiazolesulfenamide
• 英文别名: N-n-propyl(2-benzothiazolyl)sulfenamid；S-benzothiazol-2-yl-N-propyl-thiohydroxylamine；benzothiazole-2-sulfenic acid propylamide；Benzothiazol-2-sulfensaeure-propylamid；N-n-propyl-benzothiazolesulphenamide；N-(1,3-benzothiazol-2-ylsulfanyl)propan-1-amine
• CAS: 66552-53-2
• 化学式: C₁₀H₁₂N₂S₂
• 分子量: 224.351
• InChiKey: INLFGGOWMRGCMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  78.5
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2934999090

反应信息

• 作为反应物：
  描述：

  亚磷酸氢二甲酯 、 N-(1,3-苯并噻唑-2-基硫基)-1-丙胺 以80%的产率得到
  参考文献：
  名称：

  TORII S.; SAYO N.; TANAKA H., CHEM. LETT., 1980, NO 6, 695-698

  摘要：

  DOI：
• 作为产物：
  描述：

  正丙胺 、 二硫化二苯并噻唑 在 高氯酸四乙基铵 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 6.0h， 生成 N-(1,3-苯并噻唑-2-基硫基)-1-丙胺
  参考文献：
  名称：

  Electrosynthesis of hetero-hetero atom bonds. 2. An efficient preparation of (2-benzothiazolyl)- and thiocarbamoylsulfenamides by electrolytic cross-coupling reaction of 2-mercaptobenzothiazole, bis(2-benzothiazolyl) disulfide, and/or bis(dialkylthiocarbamoyl) disulfides with various amines

  摘要：

  DOI：

  10.1021/jo00410a025

文献信息

• Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S–H/N–H
  作者：Shanyu Tang、Yan Liu、Longjia Li、Xuanhe Ren、Jiao Li、Guanyu Yang、Heng Li、Bingxin Yuan

  DOI：10.1039/c8ob03211d

  日期：——

  The synthesis of sulfenamides via the oxidant- and metal-free electrochemical dehydrogenative coupling reaction of thiols and amines.

  通过硫醇和胺的氧化和无金属电化学脱氢偶联反应合成亚磺酰胺。
• Reusable cobalt-phthalocyanine in water: efficient catalytic aerobic oxidative coupling of thiols to construct S–N/S–S bonds
  作者：Yingchao Dou、Xin Huang、Hao Wang、Liting Yang、Heng Li、Bingxin Yuan、Guanyu Yang

  DOI：10.1039/c7gc00401j

  日期：——

  A new aerobic oxidative coupling of thiols in water to construct sulfenamides or disulfides was developed, utilizing cobalt(II)phthalocyanine-tetra-sodium sulfonate as the catalyst and O2 as the oxidant. The mother liquor could be recycled up to 20 times with negligible loss of activity and only a minor decrease of product yield.

  以钴（II）酞菁-四磺酸钠为催化剂，以O 2为氧化剂，开发了一种新的水中硫醇的好氧氧化偶联反应，以构建亚磺酰胺或二硫化物。母液可循环使用多达20次，而活性损失可忽略不计，而产品收率仅略有下降。
• REACTION OF SULFENAMIDES WITH DI-ALKYL AND TRIALKYL PHOSPHITES.AN EFFICIENT SYNTHESIS OF PHOSPHORAMIDATES BY UNUSUAL SUBSTITUTION AT S–N BOND IN (2-BENZOTHIAZOLYL)SULFENAMIDES
  作者：Sigeru Torii、Noboru Sayo、Hideo Tanaka

  DOI：10.1246/cl.1980.695

  日期：1980.6.5

  Regioselective attack of the trivalent phosphorus atom of dialkyl and trialkyl phosphites on either nitrogen or sulfur atom of sulfenamides has been found. The reaction of phenylsulfenamides with dialkyl phosphites yielded phosphorothiolates, whereas the treatment of (2-benzothiazolyl)sulfenamides with dialkyl and trialkyl phosphites gave phosphoramidates in excellent yields.

  发现二烷基和三烷基磷酸酯的三价磷原子对硫氨素中的氮或硫原子进行区域选择性攻击。苯基硫氨素与二烷基磷酸酯反应生成了磷硫酸盐，而（2-苯并噻唑基）硫氨素与二烷基和三烷基磷酸酯反应则优良地生成了磷酰胺。
• METHOD FOR MANUFACTURING RUBBER COMPOSITION
  申请人：Bridgestone Corporation

  公开号：EP2623546A1

  公开（公告）日：2013-08-07

  The present invention is a method for producing a rubber composition containing a rubber component (A) of at least one selected from natural rubbers and synthetic dienic rubbers, a filler containing an inorganic filler (B), a silane coupling agent (C), at least one vulcanization accelerator (D) selected from guanidines, sulfenamides and thiazoles, and an organic acid compound (E), wherein the rubber composition is kneaded in plural stages, the rubber component (A), all or a part of the inorganic filler (B), all or a part of the silane coupling agent (C), the vulcanization accelerator (D) and the organic acid compound (E) are kneaded in the first stage of kneading, and the number of molecules X of the organic acid compound (E) in the rubber composition in the first stage is in a relation of the following formula [1] relative to the number of molecules Y of the vulcanization accelerator (D) therein. The production method enables production of a rubber composition having a low-heat-generation property while successfully preventing the coupling function activity of the silane coupling agent from lowering. 0 ≤ X ≤ 1.5 x Y [1]

  本发明是一种生产橡胶组合物的方法，该橡胶组合物含有至少一种选自天然橡胶和合成二元橡胶的橡胶组分（A），一种含有无机填料（B）、硅烷偶联剂（C）、至少一种选自胍类、亚磺酰胺类和噻唑类的硫化促进剂（D）以及一种有机酸化合物（E）的填料，其中橡胶组合物分多个阶段捏合、在第一捏合阶段捏合橡胶成分（A）、全部或部分无机填料（B）、全部或部分硅烷偶联剂（C）、硫化促进剂（D）和有机酸化合物（E），且第一阶段橡胶组合物中有机酸化合物（E）的分子数 X 相对于其中硫化促进剂（D）的分子数 Y 的关系如下式[1]。该生产方法可生产出具有低发热特性的橡胶组合物，同时成功防止硅烷偶联剂的偶联功能活性降低。0 ≤ X ≤ 1.5 x Y [1]
• METHOD FOR PRODUCING RUBBER COMPOSITION
  申请人：Bridgestone Corporation

  公开号：EP2703428A1

  公开（公告）日：2014-03-05

  The invention is a process for producing a rubber composition containing at least one rubber component (A) selected from natural rubbers and synthetic diene rubbers, a filler containing an inorganic filler (B), a silane coupling agent (C) and a vulcanization accelerator (D), wherein the rubber composition is kneaded in multiple stages, the rubber component (A), all or a portion of the inorganic filler (B), all or a portion of the silane coupling agent (C) and the vulcanization accelerator (D) are added and kneaded in the first stage of kneading, and the specific energy for kneading in the first stage is from 0.05 to 1.50 kWh/kg. The specific energy is obtained by dividing the power consumption by the motor in the kneading device in the first stage of kneading by the total mass of the rubber composition therein. In the process, the coupling function activity can be further increased and a rubber composition favorably having a low-heat-generation property and having good abrasion resistance can be obtained.

  本发明是一种生产橡胶组合物的工艺，该橡胶组合物含有至少一种选自天然橡胶和合成二烯橡胶的橡胶组分（A）、一种含有无机填料（B）的填料、一种硅烷偶联剂（C）和一种硫化促进剂（D），其中橡胶组合物分多个阶段捏合、在第一阶段混炼中加入并混炼橡胶成分 (A)、全部或部分无机填料 (B)、全部或部分硅烷偶联剂 (C) 和硫化促进剂 (D)，第一阶段混炼的比能量为 0.05 至 1.50 千瓦时/千克。比能量是通过将第一阶段混炼中混炼装置中电机的耗电量除以其中橡胶组合物的总质量得出的。在此过程中，耦合功能活性可进一步提高，并可获得具有低发热特性和良好耐磨性的橡胶组合物。