(4,4'-dimethyl-2,2'-bipyridine)2OsCl2 | 115304-16-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (4,4'-dimethyl-2,2'-bipyridine)2OsCl2
• 英文别名: osmium(II) bis(4,4'-dimethyl-2,2'-bipyridine) dichloride；Os(4,4'-dimethyl-2,2'-bipyridine)2Cl2；[Os(dm-bpy)2Cl2]；dichloroosmium;4-methyl-2-(4-methylpyridin-2-yl)pyridine
• CAS: 115304-16-0
• 化学式: C₂₄H₂₄Cl₂N₄Os
• 分子量: 629.587
• InChiKey: BTCMOGFGMDCNDP-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ammonium hexafluorophosphate 、 4,4'-二甲基-2,2'-联吡啶 、 (4,4'-dimethyl-2,2'-bipyridine)2OsCl2 以 乙醇 、 水 为溶剂， 以30-45的产率得到osmium(II) tris(4,4'-dimethyl-2,2'-bipyridine) hexafluorophosphate
  参考文献：
  名称：

  Johnson, Susan R.; David Westmoreland; Caspar, Jonathan V., Inorganic Chemistry, 1988, vol. 27, # 18, p. 3195 - 3200

  摘要：

  DOI：
• 作为产物：
  描述：

  4,4'-二甲基-2,2'-联吡啶 、 diammonium hexachloroosmate(IV) 在 Na₂S₂O₄ 作用下， 以 乙二醇 为溶剂， 生成 (4,4'-dimethyl-2,2'-bipyridine)2OsCl2
  参考文献：
  名称：

  Osmium Complex Grafted on a Carbon Electrode Surface as a Mediator for a Bioelectrocatalytic Reaction

  摘要：

  提出了一种用氧化还原活性胺对碳电极进行电化学修饰的新方法，用于介导酶与电极之间的电子转移。以组胺配位的 Os 复合物作为氧化还原胺模型进行了合成。该复合物的电氧化作用在氨基的氮原子和电极表面的碳原子之间产生了稳定的共价连接。共价连接的 Os 复合物在电极上显示出良好的氧化还原反应，作为电极与模型酶（依赖 PQQ 的水溶性葡萄糖脱氢酶）之间的电子转移介质，具有很高的活性。

  DOI：

  10.1246/cl.2006.1244

文献信息

• A Laccase-Wiring Redox Hydrogel for Efficient Catalysis of O₂ Electroreduction
  作者：Nicolas Mano、Valentine Soukharev、Adam Heller

  DOI：10.1021/jp055654e

  日期：2006.6.1

  Laccase was earlier wired to yield an O-2 electroreduction catalyst greatly outperforming platinum and its alloys. Here we describe the design, synthesis optimization of the composition, and characterization of the +0.55 V (AgAgCl) laccase-wiring redox hydrogel, with an apparent electron diffusion coefficient (D-app) of 7.6x10(-7) cm(2) s(-1). The high D-app results in the tethering of redox centers to the polymer backbone through eight-atom-long spacer arms, which facilitate collisional electron transfer between proximal redox centers. The O-2 flux-limited, true-area-based current density was increased from the earlier reported 560 to 860 mu A cm(-2). When the O-2 diffusion to the 7-mu m-diameter carbon fiber cathode was cylindrical, half of the O-2 flux-limited current was reached already at 0.62 V and 90% at 0.56 V vs Ag/AgCl, merely -0.08 and -0.14 V versus the 0.7 V (Ag/AgCl) reversible O-2/H2O half-cell potential at pH 5.
• Johnson, Susan R.; David Westmoreland; Caspar, Jonathan V., Inorganic Chemistry, 1988, vol. 27, # 18, p. 3195 - 3200
  作者：Johnson, Susan R.、David Westmoreland、Caspar, Jonathan V.、Barqawi, Khaled R.、Meyer, Thomas J.

  DOI：——

  日期：——
• Osmium Complex Grafted on a Carbon Electrode Surface as a Mediator for a Bioelectrocatalytic Reaction
  作者：Seiya Tsujimura、Aya Katayama、Kenji Kano

  DOI：10.1246/cl.2006.1244

  日期：2006.11

  A novel electrochemical modification method of carbon electrodes with redox active amines is proposed for mediated electron transfer between enzymes and electrodes. Histamine-coordinated Os complex was synthesized as a model redox amine. The electro-oxidation of the complex generated a stable covalent linkage between the nitrogen atom of the amino group and the carbon atom of the electrode surface. The covalent-linked Os complex on the electrode showed a good redox response and a high activity as an electron-transfer mediator between the electrode and a model enzyme: PQQ-dependant water-soluble glucose dehydrogenase.

  提出了一种用氧化还原活性胺对碳电极进行电化学修饰的新方法，用于介导酶与电极之间的电子转移。以组胺配位的 Os 复合物作为氧化还原胺模型进行了合成。该复合物的电氧化作用在氨基的氮原子和电极表面的碳原子之间产生了稳定的共价连接。共价连接的 Os 复合物在电极上显示出良好的氧化还原反应，作为电极与模型酶（依赖 PQQ 的水溶性葡萄糖脱氢酶）之间的电子转移介质，具有很高的活性。