4-<4-(3-Hydroxyphenoxy)phenoxy>benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-<4-(3-Hydroxyphenoxy)phenoxy>benzoic acid
• 英文别名: 4-[4-(3-Hydroxyphenoxy)phenoxy]benzoic acid
• 化学式: C₁₉H₁₄O₅
• 分子量: 322.317
• InChiKey: XMZOYPLXDPPWBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1,4-二氯苯 在 氢氧化钾 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 4-<4-(3-Hydroxyphenoxy)phenoxy>benzoic acid
  参考文献：
  名称：

  Studies on Selective Nucleophilic Substitution Reactions of [(Cyclopentadienyl)(1,3- and 1,4-dichlorobenzene)Fe]+PF6- Complexes: Applications to the Synthesis of Polymer Monomers

  摘要：

  Selective displacement of chloride from cyclopentadienyl(1,4-dichlorobenzene)iron(1+) by a series of aryl oxide and amine nucleophiles is described. The methodology, coupled with decomplexation of the product organometallics, allows access to a series of para-disubstituted benzene derivatives that are of potential value in the construction of unusual polymers. Four such compounds, derived from sequential addition of 4-hydroxybenzoic ester and hydroquinone or resorcinol monophenoxide to the 1,4- and 1,3-dichlorobenzene-FeCp complexes, were subjected to polyesterification reactions. Previously unreported isoregic poly(ether-esters) were-prepared and characterized.

  DOI：

  10.1021/jo00095a036

文献信息

• Pearson Anthony J., Gelormini Ann M., J. Org. Chem, 59 (1994) N 16, S 4561-4570
  作者：Pearson Anthony J., Gelormini Ann M.

  DOI：——

  日期：——
• Studies on Selective Nucleophilic Substitution Reactions of [(Cyclopentadienyl)(1,3- and 1,4-dichlorobenzene)Fe]+PF6- Complexes: Applications to the Synthesis of Polymer Monomers
  作者：Anthony J. Pearson、Ann M. Gelormini

  DOI：10.1021/jo00095a036

  日期：1994.8

  Selective displacement of chloride from cyclopentadienyl(1,4-dichlorobenzene)iron(1+) by a series of aryl oxide and amine nucleophiles is described. The methodology, coupled with decomplexation of the product organometallics, allows access to a series of para-disubstituted benzene derivatives that are of potential value in the construction of unusual polymers. Four such compounds, derived from sequential addition of 4-hydroxybenzoic ester and hydroquinone or resorcinol monophenoxide to the 1,4- and 1,3-dichlorobenzene-FeCp complexes, were subjected to polyesterification reactions. Previously unreported isoregic poly(ether-esters) were-prepared and characterized.