propane-1,2,3-triyl tris(hydrogen sulfate) | 52178-46-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: propane-1,2,3-triyl tris(hydrogen sulfate)
• 英文别名: 1,2,3-tris-sulfooxy-propane；1,2,3-Tris-sulfooxy-propan；Glycerintrischwefelsaeure；1,3-disulfooxypropan-2-yl hydrogen sulfate
• CAS: 52178-46-8
• 化学式: C₃H₈O₁₂S₃
• 分子量: 332.287
• InChiKey: OGRFVIJJZLVPQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  216
• 氢给体数：
  3
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  1-丁基吡咯烷 、 propane-1,2,3-triyl tris(hydrogen sulfate) 生成
  参考文献：
  名称：

  WO2008/95069

  摘要：

  公开号：
• 作为产物：
  描述：

  甘油 在 磺酰氯 作用下， 生成 propane-1,2,3-triyl tris(hydrogen sulfate)
  参考文献：
  名称：

  Claesson, Journal fur praktische Chemie (Leipzig 1954), 1879, vol. <2> 20, p. 4

  摘要：

  DOI：
• 作为试剂：
  描述：

  4-羟基香豆素 、 肉桂醛 在 propane-1,2,3-triyl tris(hydrogen sulfate) 作用下， 以 水 为溶剂， 反应 0.17h， 以85%的产率得到3,3'-(3-phenylprop-2-ene-1,1-diyl)bis (4-hydroxy-2H-chromen-2-one)
  参考文献：
  名称：

  Propane-1,2,3-triyl tris(hydrogen sulfate): A mild and efficient recyclable catalyst for the synthesis of biscoumarin derivatives in water and solvent-free conditions

  摘要：

  A simple, efficient, and ecofriendly procedure has been developed using propane-1,2,3-triyl tris(hydrogen sulfate) as a catalyst for the synthesis of biscoumarin derivatives in water and solvent-free conditions. The significant features of the present protocol are simplicity, environmentally benign, high yields, no chromatographic separation, and recyclability of the catalyst. (C) 2013 Ramin Rezaei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2013.10.033

文献信息

• Incredible Role of Glycerol in Multicomponent Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones and 1-Amidoalkyl-2-naphthols
  作者：Maryam Hajjami、Fariba Bakhti、Elahe Ghiasbeygi

  DOI：10.5562/cca2637

  日期：——

  An efficient and green synthesis of 1-amidoalkyl-2-naphthols via one-pot three-component condensation of aromatic aldehydes, acetamide and 2-naphthol in the presence of catalytic amounts of glycerosulfonic acid in glycerol as a green solvent was elaborated. Also a simple method for the one-pot three-component synthesis of 2,3-dihydroquinazoline-4(1H)-ones using of isatoic anhydride, aldehydes and ammonium acetate in the presence of glycerol as a green catalyst and solvent was described. In this light we introduced the brilliant and valuable role of glycerol in the synthesis of 2,3-dihydroquinazoline-4(1H)ones and 1-amidoalkyl-2-naphthols.
• Claesson, Journal fur praktische Chemie (Leipzig 1954), 1879, vol. <2> 20, p. 4
  作者：Claesson

  DOI：——

  日期：——
• WO2008/95069
  申请人：——

  公开号：——

  公开（公告）日：——
• Propane-1,2,3-triyl tris(hydrogen sulfate): A mild and efficient recyclable catalyst for the synthesis of biscoumarin derivatives in water and solvent-free conditions
  作者：Ramin Rezaei、Fatemeh Moezzi、Mohammad Mahdi Doroodmand

  DOI：10.1016/j.cclet.2013.10.033

  日期：2014.1

  A simple, efficient, and ecofriendly procedure has been developed using propane-1,2,3-triyl tris(hydrogen sulfate) as a catalyst for the synthesis of biscoumarin derivatives in water and solvent-free conditions. The significant features of the present protocol are simplicity, environmentally benign, high yields, no chromatographic separation, and recyclability of the catalyst. (C) 2013 Ramin Rezaei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.